Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1485
  Reference Plasmid   1111525849475512_bin.7__k141_246350
  Reference Plasmid Size   3578
  Reference Plasmid GC Content   0.61
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0000026 MNGCOOOA_00002 508 3 Skin 0.43 protein_coding synonymous_variant LOW 75C>T Gly25Gly
M0000027 MNGCOOOA_00002 790 4 Skin 0.57 protein_coding synonymous_variant LOW 357C>T Asp119Asp
M0000028 MNGCOOOA_00003 1140 4 Skin 0.57 protein_coding upstream_gene_variant MODIFIER -3A>C None
M0000029 MNGCOOOA_00003 1150 4 Skin 0.57 protein_coding missense_variant MODERATE 8A>C Asn3Thr
M0000030 MNGCOOOA_00003 1189 4 Skin 0.57 protein_coding missense_variant MODERATE 47G>C Ser16Thr
M0000031 MNGCOOOA_00003 1236 4 Skin 0.57 protein_coding missense_variant MODERATE 94C>T Pro32Ser
M0000032 MNGCOOOA_00003 1238 4 Skin 0.57 protein_coding synonymous_variant LOW 96A>C Pro32Pro
M0000033 MNGCOOOA_00003 1244 4 Skin 0.57 protein_coding synonymous_variant LOW 102C>T Gly34Gly
M0000034 MNGCOOOA_00003 1247 4 Skin 0.57 protein_coding synonymous_variant LOW 105C>T Thr35Thr
M0000035 MNGCOOOA_00003 1250 4 Skin 0.57 protein_coding synonymous_variant LOW 108G>C Thr36Thr
M0000036 MNGCOOOA_00003 1254 4 Skin 0.57 protein_coding missense_variant MODERATE 112A>C Lys38Gln
M0000037 MNGCOOOA_00003 1265 4 Skin 0.57 protein_coding synonymous_variant LOW 123A>T Gly41Gly
M0000038 MNGCOOOA_00003 1269 4 Skin 0.57 protein_coding missense_variant MODERATE 127T>G Ser43Ala
M0000039 MNGCOOOA_00003 1271 4 Skin 0.57 protein_coding synonymous_variant LOW 129T>C Ser43Ser
M0000040 MNGCOOOA_00003 1277 4 Skin 0.57 protein_coding synonymous_variant LOW 135T>C Asp45Asp
M0000041 MNGCOOOA_00001 2196 5 Skin 0.71 protein_coding downstream_gene_variant MODIFIER *1775A>T None
M0000042 MNGCOOOA_00004 3090 4 Skin 0.57 protein_coding missense_variant MODERATE 385C>A Gln129Lys
M0000043 MNGCOOOA_00002 592 3 Skin 0.43 protein_coding synonymous_variant LOW 159A>G Gln53Gln
M0000044 MNGCOOOA_00002 625 4 Skin 0.57 protein_coding synonymous_variant LOW 192C>T Gly64Gly
M0000045 MNGCOOOA_00003 2003 3 Skin 0.43 protein_coding synonymous_variant LOW 861T>C Gly287Gly
M0000046 MNGCOOOA_00004 2571 3 Skin 0.43 protein_coding missense_variant MODERATE 904G>A Glu302Lys






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
MNGCOOOA_00001 3.D.4.3.3 84 1.1e-56 1 119 1.0000 1.9194 3 Primary Active Transporters 3.D Oxidoreduction-driven transporters 3.D.4 The Proton-translocating Cytochrome Oxidase (COX) Superfamily
MNGCOOOA_00002 3.D.4.3.3 95.6 3.5e-114 1 203 1.0000 3.2742 3 Primary Active Transporters 3.D Oxidoreduction-driven transporters 3.D.4 The Proton-translocating Cytochrome Oxidase (COX) Superfamily
MNGCOOOA_00003 3.D.4.3.3 92.3 1.5e-172 1 311 1.0000 5.0161 3 Primary Active Transporters 3.D Oxidoreduction-driven transporters 3.D.4 The Proton-translocating Cytochrome Oxidase (COX) Superfamily