Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1488
  Reference Plasmid   1111525849475912_bin.18__k141_92511
  Reference Plasmid Size   11526
  Reference Plasmid GC Content   0.65
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0000156 PJHFCPOI_00003 3903 11 Skin 0.73 protein_coding missense_variant MODERATE 232G>A Val78Ile
M0000157 PJHFCPOI_00004 5420 3 Skin 0.20 protein_coding synonymous_variant LOW 102C>A Ala34Ala
M0000158 PJHFCPOI_00004 5576 11 Skin 0.73 protein_coding synonymous_variant LOW 258T>C Asp86Asp
M0000159 PJHFCPOI_00004 5615 10 Skin 0.67 protein_coding synonymous_variant LOW 297T>C Asn99Asn
M0000160 PJHFCPOI_00004 5690 10 Skin 0.67 protein_coding synonymous_variant LOW 372C>T Asp124Asp
M0000161 PJHFCPOI_00004 5705 10 Skin 0.67 protein_coding synonymous_variant LOW 387C>G Gly129Gly
M0000162 PJHFCPOI_00007 8263 8 Skin 0.53 protein_coding missense_variant MODERATE 625T>G Leu209Val
M0000163 PJHFCPOI_00007 8382 8 Skin 0.53 protein_coding synonymous_variant LOW 744G>A Val248Val
M0000164 PJHFCPOI_00007 8404 8 Skin 0.53 protein_coding missense_variant MODERATE 766A>C Ile256Leu
M0000165 PJHFCPOI_00008 9059 7 Skin 0.47 protein_coding missense_variant MODERATE 703C>G Leu235Val
M0000166 PJHFCPOI_00008 11489 7 Skin 0.47 protein_coding upstream_gene_variant MODIFIER -1728G>A None
M0000167 PJHFCPOI_00002 3213 3 Skin 0.20 protein_coding synonymous_variant LOW 246T>C Gly82Gly
M0000168 PJHFCPOI_00004 5753 4 Skin 0.27 protein_coding synonymous_variant LOW 435C>G Val145Val
M0000169 PJHFCPOI_00004 5798 4 Skin 0.27 protein_coding synonymous_variant LOW 480C>T Thr160Thr
M0000170 PJHFCPOI_00004 5810 4 Skin 0.27 protein_coding synonymous_variant LOW 492T>C Asp164Asp
M0000171 PJHFCPOI_00004 5811 4 Skin 0.27 protein_coding missense_variant MODERATE 493A>G Thr165Ala
M0000172 PJHFCPOI_00004 5849 4 Skin 0.27 protein_coding synonymous_variant LOW 531C>G Ala177Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term