Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1495
  Reference Plasmid   1111525849478044_bin.18__k141_520899
  Reference Plasmid Size   14346
  Reference Plasmid GC Content   0.66
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0000185 HEFHOLLH_00003 8469 23 Skin 0.49 protein_coding upstream_gene_variant MODIFIER -4339G>A None
M0000186 HEFHOLLH_00007 13432 21 Skin 0.45 protein_coding downstream_gene_variant MODIFIER *3158G>A None
M0000187 HEFHOLLH_00007 13761 20 Skin 0.43 protein_coding downstream_gene_variant MODIFIER *3487T>C None
M0000188 HEFHOLLH_00007 14290 18 Skin 0.38 protein_coding downstream_gene_variant MODIFIER *4016C>T None
M0000189 HEFHOLLH_00005 6541 15 Skin 0.32 protein_coding missense_variant MODERATE 235A>G Ser79Gly
M0000190 HEFHOLLH_00005 6918 14 Skin 0.30 protein_coding synonymous_variant LOW 612C>T Asp204Asp
M0000191 HEFHOLLH_00005 6940 14 Skin 0.30 protein_coding missense_variant MODERATE 634C>G Leu212Val
M0000192 HEFHOLLH_00005 6865 3 Skin 0.06 protein_coding missense_variant MODERATE 559A>G Ser187Gly
M0000193 HEFHOLLH_00003 3077 8 Skin 0.17 protein_coding missense_variant MODERATE 1054C>A His352Asn
M0000194 HEFHOLLH_00003 4007 7 Skin 0.15 protein_coding missense_variant MODERATE 124A>G Ile42Val
M0000195 HEFHOLLH_00005 6507 5 Skin 0.11 protein_coding synonymous_variant LOW 201T>C Phe67Phe
M0000196 HEFHOLLH_00005 6543 4 Skin 0.09 protein_coding synonymous_variant LOW 237C>T Ser79Ser
M0000197 HEFHOLLH_00005 6606 4 Skin 0.09 protein_coding synonymous_variant LOW 300T>C Phe100Phe






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term