Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1501
  Reference Plasmid   1111525849478145_bin.27__k141_140599
  Reference Plasmid Size   15932
  Reference Plasmid GC Content   0.57
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0117367 BPHMDFNJ_00006 7406 3 Oral 0.75 protein_coding upstream_gene_variant MODIFIER -409T>C None
M0117368 BPHMDFNJ_00006 7562 3 Oral 0.75 protein_coding upstream_gene_variant MODIFIER -253A>G None
M0117369 BPHMDFNJ_00006 7583 3 Oral 0.75 protein_coding upstream_gene_variant MODIFIER -232A>C None
M0117370 BPHMDFNJ_00006 7699 3 Oral 0.75 protein_coding upstream_gene_variant MODIFIER -116T>C None
M0117371 BPHMDFNJ_00006 7829 3 Oral 0.75 protein_coding synonymous_variant LOW 15T>C Leu5Leu
M0117372 BPHMDFNJ_00006 7946 3 Oral 0.75 protein_coding synonymous_variant LOW 132A>G Thr44Thr
M0117373 BPHMDFNJ_00006 8046 3 Oral 0.75 protein_coding missense_variant MODERATE 232A>G Ser78Gly
M0117374 BPHMDFNJ_00006 8174 3 Oral 0.75 protein_coding synonymous_variant LOW 360T>C Asp120Asp
M0117375 BPHMDFNJ_00006 8255 3 Oral 0.75 protein_coding synonymous_variant LOW 441T>C Ala147Ala
M0117376 BPHMDFNJ_00006 8969 3 Oral 0.75 protein_coding synonymous_variant LOW 1155T>C Val385Val
M0117377 BPHMDFNJ_00006 8995 3 Oral 0.75 protein_coding missense_variant MODERATE 1181T>C Ile394Thr
M0117378 BPHMDFNJ_00006 9186 3 Oral 0.75 protein_coding missense_variant MODERATE 1372A>C Met458Leu
M0117379 BPHMDFNJ_00006 9320 3 Oral 0.75 protein_coding synonymous_variant LOW 1506A>G Ala502Ala
M0117380 BPHMDFNJ_00006 9368 3 Oral 0.75 protein_coding synonymous_variant LOW 1554C>T Asn518Asn
M0117381 BPHMDFNJ_00006 9413 3 Oral 0.75 protein_coding synonymous_variant LOW 1599A>G Ala533Ala
M0117382 BPHMDFNJ_00006 9503 3 Oral 0.75 protein_coding synonymous_variant LOW 1689A>G Ala563Ala
M0117383 BPHMDFNJ_00006 9830 3 Oral 0.75 protein_coding synonymous_variant LOW 2016G>C Ala672Ala
M0117384 BPHMDFNJ_00006 9932 3 Oral 0.75 protein_coding synonymous_variant LOW 2118A>G Gln706Gln
M0117385 BPHMDFNJ_00006 10029 3 Oral 0.75 protein_coding synonymous_variant LOW 2215T>C Leu739Leu
M0117386 BPHMDFNJ_00006 10251 3 Oral 0.75 protein_coding missense_variant MODERATE 2437T>A Ser813Thr
M0117387 BPHMDFNJ_00006 10401 3 Oral 0.75 protein_coding missense_variant MODERATE 2587A>G Thr863Ala
M0117388 BPHMDFNJ_00006 10445 3 Oral 0.75 protein_coding synonymous_variant LOW 2631G>C Ala877Ala
M0117389 BPHMDFNJ_00006 10448 3 Oral 0.75 protein_coding synonymous_variant LOW 2634G>C Ala878Ala
M0117390 BPHMDFNJ_00006 10475 3 Oral 0.75 protein_coding synonymous_variant LOW 2661T>C Gly887Gly
M0117391 BPHMDFNJ_00006 10529 3 Oral 0.75 protein_coding synonymous_variant LOW 2715A>G Ala905Ala
M0117392 BPHMDFNJ_00006 10532 3 Oral 0.75 protein_coding synonymous_variant LOW 2718C>T Phe906Phe
M0117393 BPHMDFNJ_00006 10535 3 Oral 0.75 protein_coding synonymous_variant LOW 2721C>G Gly907Gly
M0117394 BPHMDFNJ_00006 10621 3 Oral 0.75 protein_coding missense_variant MODERATE 2807C>A Thr936Lys
M0117395 BPHMDFNJ_00006 10622 3 Oral 0.75 protein_coding synonymous_variant LOW 2808A>G Thr936Thr
M0117396 BPHMDFNJ_00006 10638 3 Oral 0.75 protein_coding missense_variant MODERATE 2824A>G Ile942Val
M0117397 BPHMDFNJ_00006 10640 3 Oral 0.75 protein_coding synonymous_variant LOW 2826C>T Ile942Ile
M0117398 BPHMDFNJ_00006 10745 3 Oral 0.75 protein_coding synonymous_variant LOW 2931C>T Gly977Gly
M0117399 BPHMDFNJ_00006 10814 3 Oral 0.75 protein_coding synonymous_variant LOW 3000T>C Ser1000Ser
M0117400 BPHMDFNJ_00006 10847 3 Oral 0.75 protein_coding synonymous_variant LOW 3033T>C Pro1011Pro
M0117401 BPHMDFNJ_00006 10961 3 Oral 0.75 protein_coding synonymous_variant LOW 3147C>G Thr1049Thr
M0117402 BPHMDFNJ_00006 11001 3 Oral 0.75 protein_coding missense_variant MODERATE 3187G>A Ala1063Thr
M0117403 BPHMDFNJ_00006 11087 3 Oral 0.75 protein_coding synonymous_variant LOW 3273G>A Glu1091Glu
M0117404 BPHMDFNJ_00006 11178 3 Oral 0.75 protein_coding missense_variant MODERATE 3364G>A Ala1122Thr
M0117405 BPHMDFNJ_00006 11210 3 Oral 0.75 protein_coding synonymous_variant LOW 3396G>A Glu1132Glu
M0117406 BPHMDFNJ_00006 11256 3 Oral 0.75 protein_coding missense_variant MODERATE 3442G>A Ala1148Thr
M0117407 BPHMDFNJ_00006 11544 3 Oral 0.75 protein_coding missense_variant MODERATE 3730A>G Ser1244Gly
M0117408 BPHMDFNJ_00006 11645 3 Oral 0.75 protein_coding synonymous_variant LOW 3831A>G Lys1277Lys
M0117409 BPHMDFNJ_00006 11682 3 Oral 0.75 protein_coding missense_variant MODERATE 3868A>G Thr1290Ala
M0117410 BPHMDFNJ_00007 11941 3 Oral 0.75 protein_coding upstream_gene_variant MODIFIER -105A>G None
M0117411 BPHMDFNJ_00007 11948 3 Oral 0.75 protein_coding upstream_gene_variant MODIFIER -98C>T None
M0117412 BPHMDFNJ_00007 11952 3 Oral 0.75 protein_coding upstream_gene_variant MODIFIER -94G>T None
M0117413 BPHMDFNJ_00007 12065 3 Oral 0.75 protein_coding missense_variant MODERATE 20T>C Leu7Ser
M0117414 BPHMDFNJ_00007 12089 3 Oral 0.75 protein_coding missense_variant MODERATE 44T>C Leu15Pro
M0117415 BPHMDFNJ_00007 12224 3 Oral 0.75 protein_coding missense_variant MODERATE 179A>G Gln60Arg
M0117416 BPHMDFNJ_00007 12259 3 Oral 0.75 protein_coding synonymous_variant LOW 214T>C Leu72Leu
M0117417 BPHMDFNJ_00007 12274 3 Oral 0.75 protein_coding synonymous_variant LOW 229T>C Leu77Leu
M0117418 BPHMDFNJ_00007 12277 3 Oral 0.75 protein_coding synonymous_variant LOW 232T>C Leu78Leu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term