Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1502
  Reference Plasmid   1111525849478185_bin.5_new__k141_408202
  Reference Plasmid Size   2880
  Reference Plasmid GC Content   0.62
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0000226 BNOCNKKO_00001 494 12 Skin 0.92 protein_coding missense_variant MODERATE 459T>G Asp153Glu
M0000227 BNOCNKKO_00002 2344 3 Skin 0.23 protein_coding missense_variant MODERATE 41A>C Asn14Thr
M0000228 BNOCNKKO_00002 2538 4 Skin 0.31 protein_coding upstream_gene_variant MODIFIER -154A>T None
M0000229 BNOCNKKO_00001 288 6 Skin 0.46 protein_coding synonymous_variant LOW 253C>T Leu85Leu
M0000230 BNOCNKKO_00001 327 6 Skin 0.46 protein_coding missense_variant MODERATE 292A>G Ile98Val
M0000231 BNOCNKKO_00001 411 4 Skin 0.31 protein_coding missense_variant MODERATE 376A>G Ile126Val
M0000232 BNOCNKKO_00001 507 3 Skin 0.23 protein_coding missense_variant MODERATE 472G>A Ala158Thr
M0000233 BNOCNKKO_00002 1032 7 Skin 0.54 protein_coding synonymous_variant LOW 1353C>T Ala451Ala
M0000234 BNOCNKKO_00002 1803 7 Skin 0.54 protein_coding synonymous_variant LOW 582G>A Pro194Pro
M0000235 BNOCNKKO_00002 2061 9 Skin 0.69 protein_coding synonymous_variant LOW 324T>C Pro108Pro
M0000236 BNOCNKKO_00002 2067 9 Skin 0.69 protein_coding synonymous_variant LOW 318G>A Val106Val
M0000237 BNOCNKKO_00002 2076 9 Skin 0.69 protein_coding synonymous_variant LOW 309G>A Glu103Glu
M0000238 BNOCNKKO_00002 2100 9 Skin 0.69 protein_coding synonymous_variant LOW 285C>A Arg95Arg
M0000239 BNOCNKKO_00002 2168 9 Skin 0.69 protein_coding missense_variant MODERATE 217T>G Ser73Ala
M0000240 BNOCNKKO_00002 2178 9 Skin 0.69 protein_coding synonymous_variant LOW 207T>C Val69Val
M0000241 BNOCNKKO_00002 2193 9 Skin 0.69 protein_coding synonymous_variant LOW 192T>A Ala64Ala
M0000242 BNOCNKKO_00001 119 4 Skin 0.31 protein_coding synonymous_variant LOW 84A>C Gly28Gly
M0000243 BNOCNKKO_00001 567 4 Skin 0.31 protein_coding missense_variant MODERATE 532A>G Thr178Ala
M0000244 BNOCNKKO_00002 1104 3 Skin 0.23 protein_coding synonymous_variant LOW 1281C>T Val427Val
M0000245 BNOCNKKO_00002 1380 3 Skin 0.23 protein_coding synonymous_variant LOW 1005G>C Ser335Ser
M0000246 BNOCNKKO_00002 1389 3 Skin 0.23 protein_coding synonymous_variant LOW 996T>C Gly332Gly
M0000247 BNOCNKKO_00002 1578 5 Skin 0.38 protein_coding synonymous_variant LOW 807G>A Gln269Gln
M0000248 BNOCNKKO_00002 1614 4 Skin 0.31 protein_coding synonymous_variant LOW 771A>G Thr257Thr
M0000249 BNOCNKKO_00002 1617 4 Skin 0.31 protein_coding synonymous_variant LOW 768T>C Asp256Asp
M0000250 BNOCNKKO_00002 1631 4 Skin 0.31 protein_coding synonymous_variant LOW 754T>C Leu252Leu
M0000251 BNOCNKKO_00002 1647 4 Skin 0.31 protein_coding synonymous_variant LOW 738T>A Ala246Ala
M0000252 BNOCNKKO_00002 1650 4 Skin 0.31 protein_coding synonymous_variant LOW 735C>T Arg245Arg
M0000253 BNOCNKKO_00002 1668 4 Skin 0.31 protein_coding synonymous_variant LOW 717T>C Ile239Ile
M0000254 BNOCNKKO_00002 1710 4 Skin 0.31 protein_coding synonymous_variant LOW 675T>C Asp225Asp
M0000255 BNOCNKKO_00001 69 3 Skin 0.23 protein_coding missense_variant MODERATE 34G>C Ala12Pro
M0000256 BNOCNKKO_00001 125 3 Skin 0.23 protein_coding synonymous_variant LOW 90C>T Asn30Asn
M0000257 BNOCNKKO_00001 222 4 Skin 0.31 protein_coding missense_variant MODERATE 187G>A Val63Ile
M0000258 BNOCNKKO_00001 228 4 Skin 0.31 protein_coding missense_variant MODERATE 193T>C Phe65Leu
M0000259 BNOCNKKO_00001 234 4 Skin 0.31 protein_coding missense_variant MODERATE 199G>A Val67Ile
M0000260 BNOCNKKO_00001 252 4 Skin 0.31 protein_coding missense_variant MODERATE 217T>G Ser73Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term