Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1514
  Reference Plasmid   1111525849478674_bin.14__k141_6737
  Reference Plasmid Size   4022
  Reference Plasmid GC Content   0.72
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0002324 OLDMNGFD_00001 549 4 Skin 0.80 protein_coding missense_variant MODERATE 1195T>C Cys399Arg
M0002325 OLDMNGFD_00001 597 4 Skin 0.80 protein_coding missense_variant MODERATE 1147A>G Thr383Ala
M0002326 OLDMNGFD_00001 772 4 Skin 0.80 protein_coding synonymous_variant LOW 972G>T Leu324Leu
M0002327 OLDMNGFD_00001 778 4 Skin 0.80 protein_coding synonymous_variant LOW 966G>C Ala322Ala
M0002328 OLDMNGFD_00001 784 4 Skin 0.80 protein_coding synonymous_variant LOW 960G>A Lys320Lys
M0002329 OLDMNGFD_00001 787 4 Skin 0.80 protein_coding synonymous_variant LOW 957C>G Thr319Thr
M0002330 OLDMNGFD_00001 790 4 Skin 0.80 protein_coding synonymous_variant LOW 954C>T Asp318Asp
M0002331 OLDMNGFD_00001 793 4 Skin 0.80 protein_coding synonymous_variant LOW 951A>C Gly317Gly
M0002332 OLDMNGFD_00001 826 3 Skin 0.60 protein_coding synonymous_variant LOW 918A>G Leu306Leu
M0002333 OLDMNGFD_00001 949 3 Skin 0.60 protein_coding synonymous_variant LOW 795T>C Asn265Asn
M0002334 OLDMNGFD_00001 1021 3 Skin 0.60 protein_coding synonymous_variant LOW 723A>G Ala241Ala
M0002335 OLDMNGFD_00001 1039 3 Skin 0.60 protein_coding synonymous_variant LOW 705A>T Ala235Ala
M0002336 OLDMNGFD_00001 1472 4 Skin 0.80 protein_coding missense_variant MODERATE 272T>G Leu91Arg
M0002337 OLDMNGFD_00001 1790 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -47A>G None
M0002338 OLDMNGFD_00001 1820 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -77A>G None
M0002339 OLDMNGFD_00002 2595 3 Skin 0.60 protein_coding synonymous_variant LOW 312C>G Pro104Pro
M0002340 OLDMNGFD_00003 3015 4 Skin 0.80 protein_coding synonymous_variant LOW 1005A>G Ala335Ala
M0002341 OLDMNGFD_00003 3270 4 Skin 0.80 protein_coding synonymous_variant LOW 750A>G Ala250Ala
M0002342 OLDMNGFD_00003 3551 4 Skin 0.80 protein_coding missense_variant MODERATE 469G>C Val157Leu
M0002343 OLDMNGFD_00003 3954 4 Skin 0.80 protein_coding synonymous_variant LOW 66C>G Gly22Gly
M0002344 OLDMNGFD_00003 3984 5 Skin 1.00 protein_coding synonymous_variant LOW 36A>G Ala12Ala
M0002345 OLDMNGFD_00001 2979 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -1236A>G None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term