Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1515
  Reference Plasmid   1111525849478674_bin.14__k141_88555
  Reference Plasmid Size   8917
  Reference Plasmid GC Content   0.67
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0002346 OOHEKAAF_00001 326 3 Skin 0.60 protein_coding missense_variant MODERATE 229G>C Glu77Gln
M0002347 OOHEKAAF_00001 399 3 Skin 0.60 protein_coding missense_variant MODERATE 302C>A Pro101His
M0002348 OOHEKAAF_00003 1308 4 Skin 0.80 protein_coding missense_variant MODERATE 242T>G Leu81Trp
M0002349 OOHEKAAF_00004 2203 3 Skin 0.60 protein_coding synonymous_variant LOW 702C>T Phe234Phe
M0002350 OOHEKAAF_00004 2281 4 Skin 0.80 protein_coding synonymous_variant LOW 780A>G Val260Val
M0002351 OOHEKAAF_00004 2332 4 Skin 0.80 protein_coding synonymous_variant LOW 831T>C Leu277Leu
M0002352 OOHEKAAF_00004 2373 4 Skin 0.80 protein_coding missense_variant MODERATE 872G>A Arg291Gln
M0002353 OOHEKAAF_00004 2386 4 Skin 0.80 protein_coding synonymous_variant LOW 885G>A Glu295Glu
M0002354 OOHEKAAF_00004 2434 4 Skin 0.80 protein_coding synonymous_variant LOW 933T>C Ile311Ile
M0002355 OOHEKAAF_00004 2500 4 Skin 0.80 protein_coding synonymous_variant LOW 999C>T Ala333Ala
M0002356 OOHEKAAF_00004 2668 4 Skin 0.80 protein_coding synonymous_variant LOW 1167T>C Thr389Thr
M0002357 OOHEKAAF_00004 2692 4 Skin 0.80 protein_coding synonymous_variant LOW 1191C>T Leu397Leu
M0002358 OOHEKAAF_00004 2860 4 Skin 0.80 protein_coding synonymous_variant LOW 1359T>C Ala453Ala
M0002359 OOHEKAAF_00004 2893 4 Skin 0.80 protein_coding missense_variant MODERATE 1392T>G His464Gln
M0002360 OOHEKAAF_00005 3262 4 Skin 0.80 protein_coding upstream_gene_variant MODIFIER -116A>C None
M0002361 OOHEKAAF_00005 3271 4 Skin 0.80 protein_coding upstream_gene_variant MODIFIER -107C>A None
M0002362 OOHEKAAF_00005 3354 4 Skin 0.80 protein_coding upstream_gene_variant MODIFIER -24A>G None
M0002363 OOHEKAAF_00005 3355 4 Skin 0.80 protein_coding upstream_gene_variant MODIFIER -23A>G None
M0002364 OOHEKAAF_00005 3356 4 Skin 0.80 protein_coding upstream_gene_variant MODIFIER -22T>C None
M0002365 OOHEKAAF_00005 3368 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -10G>A None
M0002366 OOHEKAAF_00005 3428 4 Skin 0.80 protein_coding synonymous_variant LOW 51C>T Ala17Ala
M0002367 OOHEKAAF_00005 3434 4 Skin 0.80 protein_coding synonymous_variant LOW 57C>T His19His
M0002368 OOHEKAAF_00005 3446 3 Skin 0.60 protein_coding missense_variant MODERATE 69A>C Glu23Asp
M0002369 OOHEKAAF_00005 3464 3 Skin 0.60 protein_coding synonymous_variant LOW 87T>C Gly29Gly
M0002370 OOHEKAAF_00005 3494 3 Skin 0.60 protein_coding synonymous_variant LOW 117C>T Arg39Arg
M0002371 OOHEKAAF_00005 3608 3 Skin 0.60 protein_coding synonymous_variant LOW 231C>G Leu77Leu
M0002372 OOHEKAAF_00005 3693 3 Skin 0.60 protein_coding missense_variant MODERATE 316A>G Ser106Gly
M0002373 OOHEKAAF_00005 3708 3 Skin 0.60 protein_coding missense_variant MODERATE 331A>G Asn111Asp
M0002374 OOHEKAAF_00005 3737 4 Skin 0.80 protein_coding synonymous_variant LOW 360A>G Gln120Gln






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term