Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1516
  Reference Plasmid   1111525849478674_bin.27__k141_103850
  Reference Plasmid Size   11019
  Reference Plasmid GC Content   0.63
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0002375 CMNMBMFO_00003 3779 4 Skin 0.40 protein_coding synonymous_variant LOW 537C>G Gly179Gly
M0002376 CMNMBMFO_00004 4624 5 Skin 0.50 protein_coding synonymous_variant LOW 336T>C Val112Val
M0002377 CMNMBMFO_00004 5530 4 Skin 0.40 protein_coding synonymous_variant LOW 1242T>C Ile414Ile
M0002378 CMNMBMFO_00004 5540 4 Skin 0.40 protein_coding missense_variant MODERATE 1252A>G Asn418Asp
M0002379 CMNMBMFO_00004 5587 4 Skin 0.40 protein_coding synonymous_variant LOW 1299T>C His433His
M0002380 CMNMBMFO_00004 5590 3 Skin 0.30 protein_coding synonymous_variant LOW 1302T>C Val434Val
M0002381 CMNMBMFO_00004 5806 3 Skin 0.30 protein_coding synonymous_variant LOW 1518A>G Glu506Glu
M0002382 CMNMBMFO_00004 5872 3 Skin 0.30 protein_coding synonymous_variant LOW 1584T>C Arg528Arg
M0002383 CMNMBMFO_00004 5878 3 Skin 0.30 protein_coding synonymous_variant LOW 1590T>C Gly530Gly
M0002384 CMNMBMFO_00004 5884 4 Skin 0.40 protein_coding synonymous_variant LOW 1596A>G Lys532Lys
M0002385 CMNMBMFO_00004 5893 3 Skin 0.30 protein_coding synonymous_variant LOW 1605G>T Leu535Leu
M0002386 CMNMBMFO_00004 5897 4 Skin 0.40 protein_coding missense_variant MODERATE 1609G>A Ala537Thr
M0002387 CMNMBMFO_00004 5899 4 Skin 0.40 protein_coding synonymous_variant LOW 1611A>G Ala537Ala
M0002388 CMNMBMFO_00004 5959 4 Skin 0.40 protein_coding synonymous_variant LOW 1671T>C Asp557Asp
M0002389 CMNMBMFO_00005 6168 3 Skin 0.30 protein_coding synonymous_variant LOW 69C>G Val23Val
M0002390 CMNMBMFO_00003 3031 3 Skin 0.30 protein_coding upstream_gene_variant MODIFIER -212T>C None
M0002391 CMNMBMFO_00003 4163 3 Skin 0.30 protein_coding synonymous_variant LOW 921C>G Val307Val
M0002392 CMNMBMFO_00004 4333 4 Skin 0.40 protein_coding synonymous_variant LOW 45C>T Pro15Pro
M0002393 CMNMBMFO_00004 4336 4 Skin 0.40 protein_coding synonymous_variant LOW 48G>T Arg16Arg
M0002394 CMNMBMFO_00001 1436 3 Skin 0.30 protein_coding synonymous_variant LOW 1074A>G Pro358Pro
M0002395 CMNMBMFO_00001 1478 3 Skin 0.30 protein_coding synonymous_variant LOW 1116G>A Ala372Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term