Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1517
  Reference Plasmid   1111525849478674_bin.27__k141_110365
  Reference Plasmid Size   5189
  Reference Plasmid GC Content   0.61
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0002396 NNHMIMAI_00002 1047 4 Skin 0.36 protein_coding synonymous_variant LOW 588G>C Ala196Ala
M0002397 NNHMIMAI_00002 1112 4 Skin 0.36 protein_coding missense_variant MODERATE 653T>C Ile218Thr
M0002398 NNHMIMAI_00003 1242 3 Skin 0.27 protein_coding missense_variant MODERATE 50G>A Arg17Gln
M0002399 NNHMIMAI_00003 1330 4 Skin 0.36 protein_coding synonymous_variant LOW 138T>G Gly46Gly
M0002400 NNHMIMAI_00003 1333 4 Skin 0.36 protein_coding synonymous_variant LOW 141C>G Ser47Ser
M0002401 NNHMIMAI_00003 1361 3 Skin 0.27 protein_coding synonymous_variant LOW 169C>T Leu57Leu
M0002402 NNHMIMAI_00003 1504 3 Skin 0.27 protein_coding synonymous_variant LOW 312T>C Pro104Pro
M0002403 NNHMIMAI_00003 1570 4 Skin 0.36 protein_coding synonymous_variant LOW 378T>C Arg126Arg
M0002404 NNHMIMAI_00003 1807 3 Skin 0.27 protein_coding synonymous_variant LOW 615T>C Asp205Asp
M0002405 NNHMIMAI_00003 2170 3 Skin 0.27 protein_coding synonymous_variant LOW 978T>C Pro326Pro
M0002406 NNHMIMAI_00003 2207 3 Skin 0.27 protein_coding missense_variant MODERATE 1015C>G Leu339Val
M0002407 NNHMIMAI_00003 2209 3 Skin 0.27 protein_coding synonymous_variant LOW 1017G>C Leu339Leu
M0002408 NNHMIMAI_00003 2211 3 Skin 0.27 protein_coding missense_variant MODERATE 1019A>G Lys340Arg
M0002409 NNHMIMAI_00003 2212 3 Skin 0.27 protein_coding synonymous_variant LOW 1020A>G Lys340Lys
M0002410 NNHMIMAI_00003 2215 3 Skin 0.27 protein_coding missense_variant MODERATE 1023C>A His341Gln
M0002411 NNHMIMAI_00003 2216 3 Skin 0.27 protein_coding missense_variant MODERATE 1024A>C Lys342Gln
M0002412 NNHMIMAI_00003 2217 3 Skin 0.27 protein_coding missense_variant MODERATE 1025A>G Lys342Arg
M0002413 NNHMIMAI_00003 2669 4 Skin 0.36 protein_coding missense_variant MODERATE 1477G>A Ala493Thr
M0002414 NNHMIMAI_00003 2791 3 Skin 0.27 protein_coding synonymous_variant LOW 1599G>T Gly533Gly
M0002415 NNHMIMAI_00003 2632 3 Skin 0.27 protein_coding synonymous_variant LOW 1440T>C His480His
M0002416 NNHMIMAI_00003 3106 3 Skin 0.27 protein_coding synonymous_variant LOW 1914A>G Gly638Gly
M0002417 NNHMIMAI_00003 3181 3 Skin 0.27 protein_coding synonymous_variant LOW 1989C>T Cys663Cys
M0002418 NNHMIMAI_00003 3370 3 Skin 0.27 protein_coding synonymous_variant LOW 2178C>T Pro726Pro
M0002419 NNHMIMAI_00003 3625 3 Skin 0.27 protein_coding synonymous_variant LOW 2433A>G Ala811Ala
M0002420 NNHMIMAI_00003 3640 3 Skin 0.27 protein_coding synonymous_variant LOW 2448G>C Val816Val
M0002421 NNHMIMAI_00003 3643 3 Skin 0.27 protein_coding synonymous_variant LOW 2451T>C Ala817Ala
M0002422 NNHMIMAI_00003 3652 3 Skin 0.27 protein_coding synonymous_variant LOW 2460A>G Thr820Thr
M0002423 NNHMIMAI_00003 3655 3 Skin 0.27 protein_coding synonymous_variant LOW 2463G>C Pro821Pro
M0002424 NNHMIMAI_00003 3656 3 Skin 0.27 protein_coding missense_variant MODERATE 2464C>G Gln822Glu
M0002425 NNHMIMAI_00003 3657 3 Skin 0.27 protein_coding missense_variant MODERATE 2465A>C Gln822Pro
M0002426 NNHMIMAI_00003 3702 3 Skin 0.27 protein_coding missense_variant MODERATE 2510A>G His837Arg
M0002427 NNHMIMAI_00001 3722 3 Skin 0.27 protein_coding upstream_gene_variant MODIFIER -3456A>G None
M0002428 NNHMIMAI_00003 2005 3 Skin 0.27 protein_coding synonymous_variant LOW 813C>T Ser271Ser
M0002429 NNHMIMAI_00003 2032 3 Skin 0.27 protein_coding synonymous_variant LOW 840A>G Gly280Gly
M0002430 NNHMIMAI_00003 2140 4 Skin 0.36 protein_coding synonymous_variant LOW 948A>C Pro316Pro






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term