Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1519
  Reference Plasmid   1111525849478674_bin.27__k141_32410
  Reference Plasmid Size   32476
  Reference Plasmid GC Content   0.61
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0002438 AANDFDGC_00001 317 3 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -287A>G None
M0002439 AANDFDGC_00007 5206 3 Skin 0.18 protein_coding missense_variant MODERATE 571A>G Thr191Ala
M0002440 AANDFDGC_00002 1207 4 Skin 0.24 protein_coding synonymous_variant LOW 129G>A Leu43Leu
M0002441 AANDFDGC_00007 5546 3 Skin 0.18 protein_coding missense_variant MODERATE 911T>C Val304Ala
M0002442 AANDFDGC_00008 5847 3 Skin 0.18 protein_coding missense_variant MODERATE 277A>G Thr93Ala
M0002443 AANDFDGC_00008 6520 3 Skin 0.18 protein_coding missense_variant MODERATE 950A>T Gln317Leu
M0002444 AANDFDGC_00010 9980 3 Skin 0.18 protein_coding missense_variant MODERATE 16G>A Gly6Ser
M0002445 AANDFDGC_00016 17797 4 Skin 0.24 protein_coding upstream_gene_variant MODIFIER -4794A>T None
M0002446 AANDFDGC_00021 18545 3 Skin 0.18 protein_coding synonymous_variant LOW 324C>A Pro108Pro
M0002447 AANDFDGC_00022 19537 6 Skin 0.35 protein_coding missense_variant MODERATE 862T>C Tyr288His
M0002448 AANDFDGC_00022 20260 5 Skin 0.29 protein_coding missense_variant MODERATE 1585A>G Thr529Ala
M0002449 AANDFDGC_00022 20308 5 Skin 0.29 protein_coding missense_variant MODERATE 1633C>G Gln545Glu
M0002450 AANDFDGC_00018 14331 3 Skin 0.18 protein_coding synonymous_variant LOW 237C>A Ala79Ala
M0002451 AANDFDGC_00022 19835 3 Skin 0.18 protein_coding missense_variant MODERATE 1160T>C Met387Thr
M0002452 AANDFDGC_00022 20138 4 Skin 0.24 protein_coding missense_variant MODERATE 1463G>A Arg488Lys






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group
AANDFDGC_00002 Arsenic (As), Antimony (Sb) 70.6 1.7e-167 1 432 0.9977 1.0070 experiment
AANDFDGC_00002 Arsenic (As), Antimony (Sb) 72 3.8e-168 1 432 0.9977 1.0070 prediction






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term