Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1541
  Reference Plasmid   1111525849479064_bin.2__k141_16284
  Reference Plasmid Size   12257
  Reference Plasmid GC Content   0.64
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0006369 NJNLAOMP_00001 350 3 Skin 0.16 protein_coding synonymous_variant LOW 183G>A Gly61Gly
M0006370 NJNLAOMP_00001 507 5 Skin 0.26 protein_coding missense_variant MODERATE 340A>G Ile114Val
M0006371 NJNLAOMP_00001 527 5 Skin 0.26 protein_coding synonymous_variant LOW 360T>C Arg120Arg
M0006372 NJNLAOMP_00001 531 5 Skin 0.26 protein_coding synonymous_variant LOW 364C>T Leu122Leu
M0006373 NJNLAOMP_00003 1903 11 Skin 0.58 protein_coding synonymous_variant LOW 921C>T Gly307Gly
M0006374 NJNLAOMP_00003 1928 11 Skin 0.58 protein_coding missense_variant MODERATE 896G>A Gly299Asp
M0006375 NJNLAOMP_00003 2439 6 Skin 0.32 protein_coding synonymous_variant LOW 385T>C Leu129Leu
M0006376 NJNLAOMP_00003 2467 6 Skin 0.32 protein_coding synonymous_variant LOW 357C>T Leu119Leu
M0006377 NJNLAOMP_00003 2506 7 Skin 0.37 protein_coding synonymous_variant LOW 318G>C Pro106Pro
M0006378 NJNLAOMP_00004 3110 6 Skin 0.32 protein_coding synonymous_variant LOW 264C>T Tyr88Tyr
M0006379 NJNLAOMP_00004 3181 8 Skin 0.42 protein_coding missense_variant MODERATE 193G>A Val65Ile
M0006380 NJNLAOMP_00005 3648 9 Skin 0.47 protein_coding synonymous_variant LOW 435G>C Gly145Gly
M0006381 NJNLAOMP_00005 3755 9 Skin 0.47 protein_coding missense_variant MODERATE 328T>A Ser110Thr
M0006382 NJNLAOMP_00005 3789 9 Skin 0.47 protein_coding synonymous_variant LOW 294C>G Gly98Gly
M0006383 NJNLAOMP_00005 3825 9 Skin 0.47 protein_coding synonymous_variant LOW 258C>T Tyr86Tyr
M0006384 NJNLAOMP_00005 3831 9 Skin 0.47 protein_coding synonymous_variant LOW 252C>G Leu84Leu
M0006385 NJNLAOMP_00005 3848 10 Skin 0.53 protein_coding missense_variant MODERATE 235A>G Ile79Val
M0006386 NJNLAOMP_00005 3861 9 Skin 0.47 protein_coding synonymous_variant LOW 222T>C Thr74Thr
M0006387 NJNLAOMP_00005 3891 7 Skin 0.37 protein_coding synonymous_variant LOW 192G>A Ala64Ala
M0006388 NJNLAOMP_00005 3897 7 Skin 0.37 protein_coding synonymous_variant LOW 186T>C Ile62Ile
M0006389 NJNLAOMP_00005 3993 7 Skin 0.37 protein_coding synonymous_variant LOW 90C>G Ser30Ser
M0006390 NJNLAOMP_00006 4782 8 Skin 0.42 protein_coding synonymous_variant LOW 489G>C Ala163Ala
M0006391 NJNLAOMP_00006 4785 8 Skin 0.42 protein_coding synonymous_variant LOW 492G>A Gly164Gly
M0006392 NJNLAOMP_00006 4858 11 Skin 0.58 protein_coding missense_variant MODERATE 565G>A Asp189Asn
M0006393 NJNLAOMP_00006 4863 11 Skin 0.58 protein_coding synonymous_variant LOW 570A>T Ala190Ala
M0006394 NJNLAOMP_00006 4923 11 Skin 0.58 protein_coding synonymous_variant LOW 630T>C Val210Val
M0006395 NJNLAOMP_00007 4955 11 Skin 0.58 protein_coding synonymous_variant LOW 18A>G Ala6Ala
M0006396 NJNLAOMP_00007 4972 11 Skin 0.58 protein_coding missense_variant MODERATE 35T>C Val12Ala
M0006397 NJNLAOMP_00007 5234 11 Skin 0.58 protein_coding synonymous_variant LOW 297G>C Ala99Ala
M0006398 NJNLAOMP_00007 5240 11 Skin 0.58 protein_coding synonymous_variant LOW 303T>C Asp101Asp
M0006399 NJNLAOMP_00001 132 3 Skin 0.16 protein_coding upstream_gene_variant MODIFIER -36A>G None
M0006400 NJNLAOMP_00001 641 5 Skin 0.26 protein_coding synonymous_variant LOW 474A>C Ala158Ala
M0006401 NJNLAOMP_00002 1105 4 Skin 0.21 protein_coding synonymous_variant LOW 193T>C Leu65Leu
M0006402 NJNLAOMP_00002 1393 5 Skin 0.26 protein_coding synonymous_variant LOW 481T>C Leu161Leu
M0006403 NJNLAOMP_00002 1411 6 Skin 0.32 protein_coding synonymous_variant LOW 499T>C Leu167Leu
M0006404 NJNLAOMP_00002 1452 6 Skin 0.32 protein_coding synonymous_variant LOW 540G>A Pro180Pro
M0006405 NJNLAOMP_00002 1455 6 Skin 0.32 protein_coding synonymous_variant LOW 543C>T Tyr181Tyr
M0006406 NJNLAOMP_00003 2038 8 Skin 0.42 protein_coding synonymous_variant LOW 786T>C Thr262Thr
M0006407 NJNLAOMP_00003 2074 5 Skin 0.26 protein_coding synonymous_variant LOW 750T>A Leu250Leu
M0006408 NJNLAOMP_00005 3551 6 Skin 0.32 protein_coding missense_variant MODERATE 532T>A Ser178Thr
M0006409 NJNLAOMP_00005 3572 6 Skin 0.32 protein_coding synonymous_variant LOW 511C>T Leu171Leu
M0006410 NJNLAOMP_00007 5210 8 Skin 0.42 protein_coding synonymous_variant LOW 273T>C Asp91Asp
M0006411 NJNLAOMP_00009 6237 3 Skin 0.16 protein_coding synonymous_variant LOW 483T>C Tyr161Tyr
M0006412 NJNLAOMP_00009 6239 4 Skin 0.21 protein_coding missense_variant MODERATE 485C>T Pro162Leu
M0006413 NJNLAOMP_00009 6245 4 Skin 0.21 protein_coding missense_variant MODERATE 491C>T Thr164Ile
M0006414 NJNLAOMP_00009 6253 4 Skin 0.21 protein_coding missense_variant MODERATE 499A>T Thr167Ser
M0006415 NJNLAOMP_00009 6267 4 Skin 0.21 protein_coding synonymous_variant LOW 513T>C Arg171Arg
M0006416 NJNLAOMP_00003 6728 3 Skin 0.16 protein_coding upstream_gene_variant MODIFIER -3905T>C None
M0006417 NJNLAOMP_00011 8248 3 Skin 0.16 protein_coding synonymous_variant LOW 891T>C Gly297Gly
M0006418 NJNLAOMP_00005 8659 3 Skin 0.16 protein_coding upstream_gene_variant MODIFIER -4577G>T None
M0006419 NJNLAOMP_00005 8744 3 Skin 0.16 protein_coding upstream_gene_variant MODIFIER -4662T>C None
M0006420 NJNLAOMP_00012 9188 3 Skin 0.16 protein_coding synonymous_variant LOW 177G>A Glu59Glu
M0006421 NJNLAOMP_00002 1203 6 Skin 0.32 protein_coding synonymous_variant LOW 291T>A Ala97Ala
M0006422 NJNLAOMP_00002 1212 6 Skin 0.32 protein_coding synonymous_variant LOW 300T>C Cys100Cys
M0006423 NJNLAOMP_00002 1215 6 Skin 0.32 protein_coding synonymous_variant LOW 303C>T His101His
M0006424 NJNLAOMP_00003 4122 5 Skin 0.26 protein_coding upstream_gene_variant MODIFIER -1299A>G None
M0006425 NJNLAOMP_00003 4130 5 Skin 0.26 protein_coding upstream_gene_variant MODIFIER -1307C>T None
M0006426 NJNLAOMP_00008 5419 7 Skin 0.37 protein_coding synonymous_variant LOW 102C>A Pro34Pro
M0006427 NJNLAOMP_00002 1521 6 Skin 0.32 protein_coding synonymous_variant LOW 609C>T Asp203Asp
M0006428 NJNLAOMP_00002 1755 6 Skin 0.32 protein_coding synonymous_variant LOW 843G>A Pro281Pro
M0006429 NJNLAOMP_00002 1794 5 Skin 0.26 protein_coding synonymous_variant LOW 882C>G Ser294Ser
M0006430 NJNLAOMP_00004 2945 5 Skin 0.26 protein_coding synonymous_variant LOW 429A>G Glu143Glu
M0006431 NJNLAOMP_00004 2969 6 Skin 0.32 protein_coding synonymous_variant LOW 405C>T Gly135Gly
M0006432 NJNLAOMP_00004 3059 5 Skin 0.26 protein_coding synonymous_variant LOW 315C>T Gly105Gly
M0006433 NJNLAOMP_00004 3062 5 Skin 0.26 protein_coding synonymous_variant LOW 312C>T Ala104Ala
M0006434 NJNLAOMP_00001 599 4 Skin 0.21 protein_coding synonymous_variant LOW 432C>T Thr144Thr
M0006435 NJNLAOMP_00002 978 3 Skin 0.16 protein_coding synonymous_variant LOW 66C>T Ala22Ala
M0006436 NJNLAOMP_00002 1050 3 Skin 0.16 protein_coding synonymous_variant LOW 138T>G Leu46Leu
M0006437 NJNLAOMP_00002 1053 3 Skin 0.16 protein_coding synonymous_variant LOW 141A>G Gln47Gln
M0006438 NJNLAOMP_00002 1054 3 Skin 0.16 protein_coding synonymous_variant LOW 142T>C Leu48Leu
M0006439 NJNLAOMP_00002 1068 3 Skin 0.16 protein_coding synonymous_variant LOW 156G>A Lys52Lys
M0006440 NJNLAOMP_00005 3477 3 Skin 0.16 protein_coding synonymous_variant LOW 606A>G Gly202Gly
M0006441 NJNLAOMP_00005 3482 3 Skin 0.16 protein_coding synonymous_variant LOW 601T>C Leu201Leu
M0006442 NJNLAOMP_00005 3483 3 Skin 0.16 protein_coding synonymous_variant LOW 600T>C Gly200Gly
M0006443 NJNLAOMP_00007 5150 7 Skin 0.37 protein_coding synonymous_variant LOW 213C>A Val71Val
M0006444 NJNLAOMP_00007 5201 7 Skin 0.37 protein_coding synonymous_variant LOW 264C>T Asn88Asn
M0006445 NJNLAOMP_00003 4238 3 Skin 0.16 protein_coding upstream_gene_variant MODIFIER -1415T>C None
M0006446 NJNLAOMP_00006 4713 4 Skin 0.21 protein_coding synonymous_variant LOW 420A>G Arg140Arg






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term