Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1548
  Reference Plasmid   1111525849479926_bin.1__k141_17564
  Reference Plasmid Size   2639
  Reference Plasmid GC Content   0.39
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0117731 JKMHBLOA_00001 640 3 Oral 1.00 protein_coding missense_variant MODERATE 392A>C Lys131Thr
M0117732 JKMHBLOA_00001 701 3 Oral 1.00 protein_coding synonymous_variant LOW 453T>C Ser151Ser
M0117733 JKMHBLOA_00001 729 3 Oral 1.00 protein_coding synonymous_variant LOW 481C>T Leu161Leu
M0117734 JKMHBLOA_00002 883 3 Oral 1.00 protein_coding synonymous_variant LOW 78T>G Leu26Leu
M0117735 JKMHBLOA_00002 898 3 Oral 1.00 protein_coding synonymous_variant LOW 93T>A Thr31Thr
M0117736 JKMHBLOA_00002 1018 3 Oral 1.00 protein_coding synonymous_variant LOW 213G>A Glu71Glu
M0117737 JKMHBLOA_00002 1048 3 Oral 1.00 protein_coding synonymous_variant LOW 243G>A Lys81Lys
M0117738 JKMHBLOA_00002 1051 3 Oral 1.00 protein_coding synonymous_variant LOW 246A>G Leu82Leu
M0117739 JKMHBLOA_00002 1060 3 Oral 1.00 protein_coding synonymous_variant LOW 255A>C Ile85Ile
M0117740 JKMHBLOA_00002 1075 3 Oral 1.00 protein_coding synonymous_variant LOW 270T>C Ile90Ile
M0117741 JKMHBLOA_00002 1111 3 Oral 1.00 protein_coding synonymous_variant LOW 306G>T Leu102Leu
M0117742 JKMHBLOA_00003 1191 3 Oral 1.00 protein_coding synonymous_variant LOW 58C>T Leu20Leu
M0117743 JKMHBLOA_00003 1208 3 Oral 1.00 protein_coding synonymous_variant LOW 75A>G Glu25Glu
M0117744 JKMHBLOA_00003 1244 3 Oral 1.00 protein_coding synonymous_variant LOW 111T>C Thr37Thr
M0117745 JKMHBLOA_00003 1250 3 Oral 1.00 protein_coding synonymous_variant LOW 117A>C Ala39Ala
M0117746 JKMHBLOA_00003 1346 3 Oral 1.00 protein_coding synonymous_variant LOW 213A>C Leu71Leu
M0117747 JKMHBLOA_00003 1388 3 Oral 1.00 protein_coding synonymous_variant LOW 255A>T Ala85Ala
M0117748 JKMHBLOA_00003 1394 3 Oral 1.00 protein_coding synonymous_variant LOW 261T>G Gly87Gly
M0117749 JKMHBLOA_00003 1420 3 Oral 1.00 protein_coding missense_variant MODERATE 287T>C Val96Ala
M0117750 JKMHBLOA_00003 1544 3 Oral 1.00 protein_coding synonymous_variant LOW 411T>C Asp137Asp
M0117751 JKMHBLOA_00003 1551 3 Oral 1.00 protein_coding missense_variant MODERATE 418G>T Gly140Trp
M0117752 JKMHBLOA_00003 1608 3 Oral 1.00 protein_coding missense_variant MODERATE 475A>G Lys159Glu
M0117753 JKMHBLOA_00003 1619 3 Oral 1.00 protein_coding synonymous_variant LOW 486A>G Lys162Lys
M0117754 JKMHBLOA_00003 1628 3 Oral 1.00 protein_coding synonymous_variant LOW 495T>C Phe165Phe
M0117755 JKMHBLOA_00003 1686 3 Oral 1.00 protein_coding missense_variant MODERATE 553T>C Phe185Leu
M0117756 JKMHBLOA_00003 1700 3 Oral 1.00 protein_coding synonymous_variant LOW 567T>C Val189Val
M0117757 JKMHBLOA_00004 2169 3 Oral 1.00 protein_coding synonymous_variant LOW 267C>T Leu89Leu
M0117758 JKMHBLOA_00004 2295 3 Oral 1.00 protein_coding synonymous_variant LOW 393T>C Ala131Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term