Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1554
  Reference Plasmid   1111525849479998_bin.4__k141_1276173
  Reference Plasmid Size   4097
  Reference Plasmid GC Content   0.38
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0117853 DDKKKNBG_00002 1515 3 Oral 1.00 protein_coding synonymous_variant LOW 285A>T Ser95Ser
M0117854 DDKKKNBG_00002 1536 3 Oral 1.00 protein_coding synonymous_variant LOW 306G>A Lys102Lys
M0117855 DDKKKNBG_00002 1659 3 Oral 1.00 protein_coding synonymous_variant LOW 429G>A Glu143Glu
M0117856 DDKKKNBG_00002 1725 3 Oral 1.00 protein_coding synonymous_variant LOW 495T>C Asn165Asn
M0117857 DDKKKNBG_00002 1801 3 Oral 1.00 protein_coding synonymous_variant LOW 571T>C Leu191Leu
M0117858 DDKKKNBG_00002 1837 3 Oral 1.00 protein_coding missense_variant MODERATE 607G>A Val203Ile
M0117859 DDKKKNBG_00002 1911 3 Oral 1.00 protein_coding synonymous_variant LOW 681G>A Thr227Thr
M0117860 DDKKKNBG_00002 1963 3 Oral 1.00 protein_coding missense_variant MODERATE 733G>A Val245Ile
M0117861 DDKKKNBG_00002 1980 3 Oral 1.00 protein_coding synonymous_variant LOW 750C>T Ile250Ile
M0117862 DDKKKNBG_00002 2070 3 Oral 1.00 protein_coding synonymous_variant LOW 840T>C Leu280Leu
M0117863 DDKKKNBG_00002 2175 3 Oral 1.00 protein_coding synonymous_variant LOW 945G>A Glu315Glu
M0117864 DDKKKNBG_00002 2187 3 Oral 1.00 protein_coding synonymous_variant LOW 957C>T Ile319Ile
M0117865 DDKKKNBG_00002 2190 3 Oral 1.00 protein_coding synonymous_variant LOW 960A>G Glu320Glu
M0117866 DDKKKNBG_00002 2328 3 Oral 1.00 protein_coding synonymous_variant LOW 1098A>T Leu366Leu
M0117867 DDKKKNBG_00002 2373 3 Oral 1.00 protein_coding synonymous_variant LOW 1143T>C Arg381Arg
M0117868 DDKKKNBG_00002 2442 3 Oral 1.00 protein_coding synonymous_variant LOW 1212T>A Ile404Ile
M0117869 DDKKKNBG_00002 2484 3 Oral 1.00 protein_coding synonymous_variant LOW 1254G>A Gln418Gln
M0117870 DDKKKNBG_00002 2514 3 Oral 1.00 protein_coding synonymous_variant LOW 1284C>T Ile428Ile
M0117871 DDKKKNBG_00002 2538 3 Oral 1.00 protein_coding synonymous_variant LOW 1308C>T Ser436Ser
M0117872 DDKKKNBG_00002 2553 3 Oral 1.00 protein_coding synonymous_variant LOW 1323C>T Leu441Leu
M0117873 DDKKKNBG_00002 2568 3 Oral 1.00 protein_coding synonymous_variant LOW 1338T>A Gly446Gly






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term