Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1559
  Reference Plasmid   1111525849480093_bin.46__k141_247358
  Reference Plasmid Size   11044
  Reference Plasmid GC Content   0.69
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0007449 OPPADBBP_00005 3573 3 Skin 0.23 protein_coding missense_variant MODERATE 289G>T Ala97Ser
M0007450 OPPADBBP_00005 3592 3 Skin 0.23 protein_coding synonymous_variant LOW 270G>C Leu90Leu
M0007451 OPPADBBP_00005 3607 3 Skin 0.23 protein_coding synonymous_variant LOW 255C>T Asp85Asp
M0007452 OPPADBBP_00005 3639 5 Skin 0.38 protein_coding synonymous_variant LOW 223T>C Leu75Leu
M0007453 OPPADBBP_00005 3790 3 Skin 0.23 protein_coding synonymous_variant LOW 72T>C Pro24Pro
M0007454 OPPADBBP_00005 3796 3 Skin 0.23 protein_coding synonymous_variant LOW 66G>A Ala22Ala
M0007455 OPPADBBP_00005 3813 3 Skin 0.23 protein_coding missense_variant MODERATE 49T>G Ser17Ala
M0007456 OPPADBBP_00005 3820 3 Skin 0.23 protein_coding synonymous_variant LOW 42A>G Ala14Ala
M0007457 OPPADBBP_00005 3831 3 Skin 0.23 protein_coding missense_variant MODERATE 31G>C Ala11Pro
M0007458 OPPADBBP_00005 3832 3 Skin 0.23 protein_coding synonymous_variant LOW 30C>G Val10Val
M0007459 OPPADBBP_00006 3960 5 Skin 0.38 protein_coding synonymous_variant LOW 714A>G Thr238Thr
M0007460 OPPADBBP_00006 4068 3 Skin 0.23 protein_coding synonymous_variant LOW 606G>A Glu202Glu
M0007461 OPPADBBP_00006 4095 3 Skin 0.23 protein_coding synonymous_variant LOW 579G>C Leu193Leu
M0007462 OPPADBBP_00006 4131 5 Skin 0.38 protein_coding synonymous_variant LOW 543T>G Leu181Leu
M0007463 OPPADBBP_00004 7032 5 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -4483A>C None
M0007464 OPPADBBP_00009 7183 4 Skin 0.31 protein_coding missense_variant MODERATE 1933C>A Pro645Thr
M0007465 OPPADBBP_00005 3192 4 Skin 0.31 protein_coding missense_variant MODERATE 670C>G Gln224Glu
M0007466 OPPADBBP_00001 100 3 Skin 0.23 protein_coding synonymous_variant LOW 45C>T Val15Val






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
OPPADBBP_00009 2.A.56.3.4 74.7 1.7e-234 1 626 0.9414 0.9935 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.56 The Tripartite ATP-independent Periplasmic Transporter (TRAP-T) Family