Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1571
  Reference Plasmid   1111525849480310_bin.13__k141_587758
  Reference Plasmid Size   10780
  Reference Plasmid GC Content   0.68
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0007613 KMABFJJF_00003 478 10 Skin 0.63 protein_coding upstream_gene_variant MODIFIER -501C>T None
M0007614 KMABFJJF_00003 1548 10 Skin 0.63 protein_coding synonymous_variant LOW 570T>C Val190Val
M0007615 KMABFJJF_00003 1798 9 Skin 0.56 protein_coding missense_variant MODERATE 820A>G Asn274Asp
M0007616 KMABFJJF_00003 1799 9 Skin 0.56 protein_coding missense_variant MODERATE 821A>T Asn274Ile
M0007617 KMABFJJF_00003 1986 8 Skin 0.50 protein_coding synonymous_variant LOW 1008T>C Val336Val
M0007618 KMABFJJF_00003 1995 9 Skin 0.56 protein_coding synonymous_variant LOW 1017T>C Asn339Asn
M0007619 KMABFJJF_00003 2343 9 Skin 0.56 protein_coding synonymous_variant LOW 1365T>C Gly455Gly
M0007620 KMABFJJF_00002 2539 8 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -1667A>C None
M0007621 KMABFJJF_00003 463 4 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -516T>C None
M0007622 KMABFJJF_00003 1008 3 Skin 0.19 protein_coding synonymous_variant LOW 30C>T Ile10Ile
M0007623 KMABFJJF_00003 1095 3 Skin 0.19 protein_coding synonymous_variant LOW 117C>T Gly39Gly
M0007624 KMABFJJF_00003 1800 3 Skin 0.19 protein_coding synonymous_variant LOW 822C>T Asn274Asn
M0007625 KMABFJJF_00002 2446 6 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -1574C>G None
M0007626 KMABFJJF_00004 2808 6 Skin 0.38 protein_coding synonymous_variant LOW 858A>C Arg286Arg
M0007627 KMABFJJF_00004 3016 4 Skin 0.25 protein_coding missense_variant MODERATE 650T>C Leu217Pro
M0007628 KMABFJJF_00004 3157 4 Skin 0.25 protein_coding missense_variant MODERATE 509A>G Glu170Gly
M0007629 KMABFJJF_00004 3198 3 Skin 0.19 protein_coding synonymous_variant LOW 468T>C Ser156Ser
M0007630 KMABFJJF_00004 3356 3 Skin 0.19 protein_coding missense_variant MODERATE 310G>A Val104Met
M0007631 KMABFJJF_00004 3607 3 Skin 0.19 protein_coding missense_variant MODERATE 59A>C Gln20Pro
M0007632 KMABFJJF_00004 3609 3 Skin 0.19 protein_coding synonymous_variant LOW 57G>A Gln19Gln
M0007633 KMABFJJF_00004 3613 3 Skin 0.19 protein_coding missense_variant MODERATE 53A>C Gln18Pro
M0007634 KMABFJJF_00004 3654 4 Skin 0.25 protein_coding synonymous_variant LOW 12G>A Ala4Ala
M0007635 KMABFJJF_00002 3672 4 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -2800A>C None
M0007636 KMABFJJF_00002 3704 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -2832C>T None
M0007637 KMABFJJF_00002 3858 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -2986C>T None
M0007638 KMABFJJF_00002 822 4 Skin 0.25 protein_coding synonymous_variant LOW 51C>T Leu17Leu
M0007639 KMABFJJF_00002 931 5 Skin 0.31 protein_coding upstream_gene_variant MODIFIER -59G>A None
M0007640 KMABFJJF_00002 4729 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -3857A>C None
M0007641 KMABFJJF_00002 4731 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -3859C>G None
M0007642 KMABFJJF_00002 4734 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -3862T>G None
M0007643 KMABFJJF_00002 4749 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -3877T>C None
M0007644 KMABFJJF_00002 4750 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -3878A>G None
M0007645 KMABFJJF_00002 4752 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -3880T>A None
M0007646 KMABFJJF_00006 4948 3 Skin 0.19 protein_coding synonymous_variant LOW 1243C>T Leu415Leu
M0007647 KMABFJJF_00006 5264 3 Skin 0.19 protein_coding synonymous_variant LOW 927T>C Tyr309Tyr
M0007648 KMABFJJF_00006 5282 3 Skin 0.19 protein_coding synonymous_variant LOW 909C>T Ser303Ser
M0007649 KMABFJJF_00006 5294 3 Skin 0.19 protein_coding synonymous_variant LOW 897T>C Ser299Ser
M0007650 KMABFJJF_00006 5309 3 Skin 0.19 protein_coding synonymous_variant LOW 882G>C Gly294Gly
M0007651 KMABFJJF_00006 5318 3 Skin 0.19 protein_coding synonymous_variant LOW 873C>G Gly291Gly
M0007652 KMABFJJF_00006 5327 3 Skin 0.19 protein_coding synonymous_variant LOW 864C>G Gly288Gly
M0007653 KMABFJJF_00006 5342 3 Skin 0.19 protein_coding synonymous_variant LOW 849C>T Leu283Leu
M0007654 KMABFJJF_00006 5375 4 Skin 0.25 protein_coding synonymous_variant LOW 816A>G Arg272Arg
M0007655 KMABFJJF_00006 5378 4 Skin 0.25 protein_coding synonymous_variant LOW 813G>A Arg271Arg
M0007656 KMABFJJF_00006 5401 4 Skin 0.25 protein_coding missense_variant MODERATE 790T>G Ser264Ala
M0007657 KMABFJJF_00006 5408 4 Skin 0.25 protein_coding synonymous_variant LOW 783T>C Ala261Ala
M0007658 KMABFJJF_00006 5420 4 Skin 0.25 protein_coding synonymous_variant LOW 771G>A Gln257Gln
M0007659 KMABFJJF_00006 5426 4 Skin 0.25 protein_coding synonymous_variant LOW 765T>C Gly255Gly
M0007660 KMABFJJF_00006 5519 4 Skin 0.25 protein_coding synonymous_variant LOW 672G>C Leu224Leu
M0007661 KMABFJJF_00006 5525 4 Skin 0.25 protein_coding synonymous_variant LOW 666G>C Arg222Arg
M0007662 KMABFJJF_00006 5558 4 Skin 0.25 protein_coding synonymous_variant LOW 633G>C Ala211Ala
M0007663 KMABFJJF_00006 5639 4 Skin 0.25 protein_coding synonymous_variant LOW 552T>C Ala184Ala
M0007664 KMABFJJF_00003 1432 3 Skin 0.19 protein_coding synonymous_variant LOW 454C>A Arg152Arg
M0007665 KMABFJJF_00003 1970 3 Skin 0.19 protein_coding missense_variant MODERATE 992A>G His331Arg






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term