Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1577
  Reference Plasmid   1111525849480358_bin.11__k141_225124
  Reference Plasmid Size   20492
  Reference Plasmid GC Content   0.70
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0007711 GGPOONBG_00011 10977 3 Skin 0.25 protein_coding missense_variant MODERATE 412T>C Ser138Pro
M0007712 GGPOONBG_00011 11075 3 Skin 0.25 protein_coding synonymous_variant LOW 510C>G Leu170Leu
M0007713 GGPOONBG_00011 11173 3 Skin 0.25 protein_coding missense_variant MODERATE 608A>T Lys203Met
M0007714 GGPOONBG_00011 11358 5 Skin 0.42 protein_coding missense_variant MODERATE 793T>G Leu265Val
M0007715 GGPOONBG_00011 11370 4 Skin 0.33 protein_coding synonymous_variant LOW 805T>C Leu269Leu
M0007716 GGPOONBG_00011 11456 3 Skin 0.25 protein_coding synonymous_variant LOW 891T>C Thr297Thr
M0007717 GGPOONBG_00012 11784 3 Skin 0.25 protein_coding missense_variant MODERATE 238G>C Ala80Pro
M0007718 GGPOONBG_00012 11846 3 Skin 0.25 protein_coding synonymous_variant LOW 300T>C Phe100Phe
M0007719 GGPOONBG_00012 11866 4 Skin 0.33 protein_coding missense_variant MODERATE 320G>A Cys107Tyr
M0007720 GGPOONBG_00013 12408 4 Skin 0.33 protein_coding synonymous_variant LOW 336A>T Gly112Gly
M0007721 GGPOONBG_00013 12417 4 Skin 0.33 protein_coding synonymous_variant LOW 345G>A Ala115Ala
M0007722 GGPOONBG_00013 12421 4 Skin 0.33 protein_coding missense_variant MODERATE 349A>G Arg117Gly
M0007723 GGPOONBG_00009 14487 3 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -4929C>T None
M0007724 GGPOONBG_00009 14492 3 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -4934C>G None
M0007725 GGPOONBG_00009 14495 3 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -4937G>C None
M0007726 GGPOONBG_00009 14516 3 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -4958T>C None
M0007727 GGPOONBG_00009 14529 3 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -4971A>G None
M0007728 GGPOONBG_00015 14687 3 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -759T>C None
M0007729 GGPOONBG_00017 14822 5 Skin 0.42 protein_coding missense_variant MODERATE 752T>C Leu251Pro
M0007730 GGPOONBG_00017 15540 3 Skin 0.25 protein_coding synonymous_variant LOW 34A>C Arg12Arg
M0007731 GGPOONBG_00017 15543 3 Skin 0.25 protein_coding missense_variant MODERATE 31G>C Ala11Pro
M0007732 GGPOONBG_00015 15688 3 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -1760C>T None
M0007733 GGPOONBG_00015 15690 3 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -1762G>C None
M0007734 GGPOONBG_00015 15698 3 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -1770G>A None
M0007735 GGPOONBG_00015 15742 3 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -1814C>G None
M0007736 GGPOONBG_00015 15762 3 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -1834G>A None
M0007737 GGPOONBG_00018 16154 3 Skin 0.25 protein_coding synonymous_variant LOW 1068A>C Gly356Gly
M0007738 GGPOONBG_00018 16289 3 Skin 0.25 protein_coding synonymous_variant LOW 933C>G Gly311Gly
M0007739 GGPOONBG_00018 16366 4 Skin 0.33 protein_coding missense_variant MODERATE 856T>G Tyr286Asp
M0007740 GGPOONBG_00018 16520 4 Skin 0.33 protein_coding synonymous_variant LOW 702C>G Leu234Leu
M0007741 GGPOONBG_00018 16523 4 Skin 0.33 protein_coding synonymous_variant LOW 699C>G Ala233Ala
M0007742 GGPOONBG_00018 16580 4 Skin 0.33 protein_coding synonymous_variant LOW 642C>G Arg214Arg
M0007743 GGPOONBG_00018 16583 4 Skin 0.33 protein_coding synonymous_variant LOW 639G>A Gly213Gly
M0007744 GGPOONBG_00018 16613 3 Skin 0.25 protein_coding synonymous_variant LOW 609C>G Leu203Leu
M0007745 GGPOONBG_00018 16694 3 Skin 0.25 protein_coding synonymous_variant LOW 528C>G Arg176Arg
M0007746 GGPOONBG_00018 16843 3 Skin 0.25 protein_coding synonymous_variant LOW 379A>C Arg127Arg
M0007747 GGPOONBG_00018 16862 3 Skin 0.25 protein_coding synonymous_variant LOW 360A>G Pro120Pro
M0007748 GGPOONBG_00018 17020 3 Skin 0.25 protein_coding missense_variant MODERATE 202G>A Val68Ile
M0007749 GGPOONBG_00018 17024 3 Skin 0.25 protein_coding synonymous_variant LOW 198T>C Gly66Gly
M0007750 GGPOONBG_00018 17072 3 Skin 0.25 protein_coding synonymous_variant LOW 150T>C Val50Val
M0007751 GGPOONBG_00015 17243 4 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -3315A>G None
M0007752 GGPOONBG_00015 17298 3 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -3370C>T None
M0007753 GGPOONBG_00019 17364 4 Skin 0.33 protein_coding missense_variant MODERATE 949G>C Val317Leu
M0007754 GGPOONBG_00019 17379 4 Skin 0.33 protein_coding missense_variant MODERATE 934A>G Ile312Val
M0007755 GGPOONBG_00019 17476 5 Skin 0.42 protein_coding synonymous_variant LOW 837T>C Ala279Ala
M0007756 GGPOONBG_00019 17538 5 Skin 0.42 protein_coding missense_variant MODERATE 775G>C Gly259Arg
M0007757 GGPOONBG_00019 17665 3 Skin 0.25 protein_coding synonymous_variant LOW 648G>A Leu216Leu
M0007758 GGPOONBG_00019 17682 3 Skin 0.25 protein_coding missense_variant MODERATE 631C>G Pro211Ala
M0007759 GGPOONBG_00019 17683 3 Skin 0.25 protein_coding synonymous_variant LOW 630G>A Pro210Pro
M0007760 GGPOONBG_00019 17698 5 Skin 0.42 protein_coding synonymous_variant LOW 615C>G Leu205Leu
M0007761 GGPOONBG_00019 17720 5 Skin 0.42 protein_coding missense_variant MODERATE 593A>C Glu198Ala
M0007762 GGPOONBG_00019 17760 5 Skin 0.42 protein_coding synonymous_variant LOW 553T>C Leu185Leu
M0007763 GGPOONBG_00007 6593 3 Skin 0.25 protein_coding missense_variant MODERATE 927G>C Met309Ile
M0007764 GGPOONBG_00007 6596 3 Skin 0.25 protein_coding synonymous_variant LOW 924G>A Glu308Glu
M0007765 GGPOONBG_00007 6644 3 Skin 0.25 protein_coding synonymous_variant LOW 876T>G Leu292Leu
M0007766 GGPOONBG_00007 6656 3 Skin 0.25 protein_coding synonymous_variant LOW 864T>C Arg288Arg
M0007767 GGPOONBG_00007 6662 3 Skin 0.25 protein_coding synonymous_variant LOW 858C>T His286His
M0007768 GGPOONBG_00007 6677 3 Skin 0.25 protein_coding missense_variant MODERATE 843C>G Phe281Leu
M0007769 GGPOONBG_00007 6679 3 Skin 0.25 protein_coding missense_variant MODERATE 841T>C Phe281Leu
M0007770 GGPOONBG_00007 6680 3 Skin 0.25 protein_coding missense_variant MODERATE 840C>A Asp280Glu
M0007771 GGPOONBG_00007 6689 3 Skin 0.25 protein_coding synonymous_variant LOW 831G>C Arg277Arg
M0007772 GGPOONBG_00007 6695 3 Skin 0.25 protein_coding synonymous_variant LOW 825C>T His275His
M0007773 GGPOONBG_00007 6699 3 Skin 0.25 protein_coding missense_variant MODERATE 821A>C Glu274Ala
M0007774 GGPOONBG_00007 6728 3 Skin 0.25 protein_coding synonymous_variant LOW 792G>C Arg264Arg
M0007775 GGPOONBG_00007 6746 3 Skin 0.25 protein_coding synonymous_variant LOW 774T>C Tyr258Tyr
M0007776 GGPOONBG_00007 6833 3 Skin 0.25 protein_coding synonymous_variant LOW 687T>C Thr229Thr
M0007777 GGPOONBG_00007 7119 3 Skin 0.25 protein_coding missense_variant MODERATE 401A>T His134Leu
M0007778 GGPOONBG_00007 7121 3 Skin 0.25 protein_coding synonymous_variant LOW 399T>C Thr133Thr
M0007779 GGPOONBG_00003 7569 3 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -4708A>G None
M0007780 GGPOONBG_00008 8202 3 Skin 0.25 protein_coding synonymous_variant LOW 576G>C Leu192Leu
M0007781 GGPOONBG_00008 8316 3 Skin 0.25 protein_coding synonymous_variant LOW 690A>C Ala230Ala
M0007782 GGPOONBG_00008 8496 3 Skin 0.25 protein_coding synonymous_variant LOW 870A>G Ala290Ala
M0007783 GGPOONBG_00009 8560 4 Skin 0.33 protein_coding synonymous_variant LOW 999A>G Ala333Ala
M0007784 GGPOONBG_00009 8561 4 Skin 0.33 protein_coding missense_variant MODERATE 998C>G Ala333Gly
M0007785 GGPOONBG_00009 8588 4 Skin 0.33 protein_coding missense_variant MODERATE 971C>T Pro324Leu
M0007786 GGPOONBG_00009 8631 3 Skin 0.25 protein_coding missense_variant MODERATE 928A>G Ser310Gly
M0007787 GGPOONBG_00009 8637 3 Skin 0.25 protein_coding missense_variant MODERATE 922T>C Cys308Arg
M0007788 GGPOONBG_00010 10158 5 Skin 0.42 protein_coding synonymous_variant LOW 540A>C Gly180Gly
M0007789 GGPOONBG_00010 10159 5 Skin 0.42 protein_coding synonymous_variant LOW 541T>C Leu181Leu
M0007790 GGPOONBG_00010 10164 5 Skin 0.42 protein_coding synonymous_variant LOW 546T>C Gly182Gly
M0007791 GGPOONBG_00012 12054 3 Skin 0.25 protein_coding missense_variant MODERATE 508T>A Trp170Arg
M0007792 GGPOONBG_00012 12055 3 Skin 0.25 protein_coding stop_gained HIGH 509G>A Trp170*
M0007793 GGPOONBG_00007 12072 3 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -4553G>C None
M0007794 GGPOONBG_00013 12081 3 Skin 0.25 protein_coding synonymous_variant LOW 9G>A Glu3Glu
M0007795 GGPOONBG_00017 15295 3 Skin 0.25 protein_coding missense_variant MODERATE 279T>G Asp93Glu
M0007796 GGPOONBG_00019 17948 4 Skin 0.33 protein_coding missense_variant MODERATE 365T>C Val122Ala
M0007797 GGPOONBG_00019 17958 4 Skin 0.33 protein_coding missense_variant MODERATE 355G>A Gly119Ser
M0007798 GGPOONBG_00020 18518 3 Skin 0.25 protein_coding synonymous_variant LOW 30A>C Ala10Ala
M0007799 GGPOONBG_00020 18554 3 Skin 0.25 protein_coding synonymous_variant LOW 66C>G Ala22Ala
M0007800 GGPOONBG_00020 18878 5 Skin 0.42 protein_coding synonymous_variant LOW 390T>C Arg130Arg
M0007801 GGPOONBG_00020 19466 3 Skin 0.25 protein_coding synonymous_variant LOW 978A>G Gly326Gly
M0007802 GGPOONBG_00017 19655 3 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -4082T>G None
M0007803 GGPOONBG_00021 20016 3 Skin 0.25 protein_coding missense_variant MODERATE 438A>T Gln146His
M0007804 GGPOONBG_00017 20460 3 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -4887T>G None
M0007805 GGPOONBG_00019 17408 3 Skin 0.25 protein_coding missense_variant MODERATE 905T>C Ile302Thr






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term