Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1584
  Reference Plasmid   1111525849480358_bin.20__k141_128656
  Reference Plasmid Size   441509
  Reference Plasmid GC Content   0.67
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0007898 EGDKDILH_00083 91097 3 Skin 0.30 protein_coding missense_variant MODERATE 748A>G Lys250Glu
M0007899 EGDKDILH_00083 91126 3 Skin 0.30 protein_coding synonymous_variant LOW 777A>G Leu259Leu
M0007900 EGDKDILH_00083 91132 3 Skin 0.30 protein_coding synonymous_variant LOW 783G>A Glu261Glu
M0007901 EGDKDILH_00083 91138 3 Skin 0.30 protein_coding missense_variant MODERATE 789A>C Gln263His
M0007902 EGDKDILH_00083 91159 3 Skin 0.30 protein_coding synonymous_variant LOW 810G>C Thr270Thr
M0007903 EGDKDILH_00083 91199 3 Skin 0.30 protein_coding missense_variant MODERATE 850A>G Met284Val
M0007904 EGDKDILH_00083 91231 3 Skin 0.30 protein_coding synonymous_variant LOW 882A>C Gly294Gly
M0007905 EGDKDILH_00083 91270 3 Skin 0.30 protein_coding synonymous_variant LOW 921T>C Arg307Arg
M0007906 EGDKDILH_00083 91405 3 Skin 0.30 protein_coding synonymous_variant LOW 1056A>G Val352Val
M0007907 EGDKDILH_00084 91477 3 Skin 0.30 protein_coding missense_variant MODERATE 11T>C Val4Ala
M0007908 EGDKDILH_00084 91502 3 Skin 0.30 protein_coding synonymous_variant LOW 36A>C Ala12Ala
M0007909 EGDKDILH_00084 91573 3 Skin 0.30 protein_coding missense_variant MODERATE 107C>A Ala36Glu
M0007910 EGDKDILH_00084 91629 3 Skin 0.30 protein_coding missense_variant MODERATE 163G>T Ala55Ser
M0007911 EGDKDILH_00084 91630 3 Skin 0.30 protein_coding missense_variant MODERATE 164C>G Ala55Gly
M0007912 EGDKDILH_00084 91632 3 Skin 0.30 protein_coding missense_variant MODERATE 166T>G Leu56Val
M0007913 EGDKDILH_00084 91673 3 Skin 0.30 protein_coding synonymous_variant LOW 207T>G Leu69Leu
M0007914 EGDKDILH_00084 91751 3 Skin 0.30 protein_coding synonymous_variant LOW 285A>C Pro95Pro
M0007915 EGDKDILH_00084 91909 3 Skin 0.30 protein_coding missense_variant MODERATE 443C>T Ala148Val






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
EGDKDILH_00032 QGP77728.1|GH23 85.7 2.01e-170 1 287 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term