Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1582
  Reference Plasmid   1111525849480358_bin.2__k141_42315
  Reference Plasmid Size   7259
  Reference Plasmid GC Content   0.31
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0007917 IKAEBCDM_00004 6094 3 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -863G>A None
M0007918 IKAEBCDM_00001 266 4 Skin 0.44 protein_coding upstream_gene_variant MODIFIER -13G>A None
M0007919 IKAEBCDM_00001 282 4 Skin 0.44 protein_coding missense_variant MODERATE 4G>A Ala2Thr
M0007920 IKAEBCDM_00001 285 4 Skin 0.44 protein_coding missense_variant MODERATE 7C>A Leu3Ile
M0007921 IKAEBCDM_00001 314 4 Skin 0.44 protein_coding synonymous_variant LOW 36G>T Val12Val
M0007922 IKAEBCDM_00001 402 4 Skin 0.44 protein_coding missense_variant MODERATE 124A>G Ser42Gly
M0007923 IKAEBCDM_00001 427 4 Skin 0.44 protein_coding missense_variant MODERATE 149T>A Ile50Asn
M0007924 IKAEBCDM_00001 717 4 Skin 0.44 protein_coding missense_variant MODERATE 439A>C Lys147Gln
M0007925 IKAEBCDM_00001 727 4 Skin 0.44 protein_coding missense_variant MODERATE 449A>G His150Arg
M0007926 IKAEBCDM_00001 921 4 Skin 0.44 protein_coding synonymous_variant LOW 643C>T Leu215Leu
M0007927 IKAEBCDM_00001 963 4 Skin 0.44 protein_coding missense_variant MODERATE 685T>G Tyr229Asp
M0007928 IKAEBCDM_00002 1150 6 Skin 0.67 protein_coding missense_variant MODERATE 124T>C Tyr42His
M0007929 IKAEBCDM_00002 1718 4 Skin 0.44 protein_coding missense_variant MODERATE 692T>C Ile231Thr
M0007930 IKAEBCDM_00002 1788 4 Skin 0.44 protein_coding synonymous_variant LOW 762A>C Ser254Ser
M0007931 IKAEBCDM_00002 1832 4 Skin 0.44 protein_coding missense_variant MODERATE 806A>G Gln269Arg
M0007932 IKAEBCDM_00002 1834 4 Skin 0.44 protein_coding missense_variant MODERATE 808G>A Val270Ile
M0007933 IKAEBCDM_00002 1875 4 Skin 0.44 protein_coding synonymous_variant LOW 849T>C Tyr283Tyr
M0007934 IKAEBCDM_00002 1889 4 Skin 0.44 protein_coding missense_variant MODERATE 863A>G Asn288Ser
M0007935 IKAEBCDM_00002 1968 4 Skin 0.44 protein_coding synonymous_variant LOW 942G>A Ala314Ala
M0007936 IKAEBCDM_00002 1986 4 Skin 0.44 protein_coding synonymous_variant LOW 960A>G Leu320Leu
M0007937 IKAEBCDM_00002 1995 4 Skin 0.44 protein_coding synonymous_variant LOW 969T>C Thr323Thr
M0007938 IKAEBCDM_00002 1999 4 Skin 0.44 protein_coding missense_variant MODERATE 973A>C Thr325Pro
M0007939 IKAEBCDM_00002 2034 4 Skin 0.44 protein_coding synonymous_variant LOW 1008G>A Ala336Ala
M0007940 IKAEBCDM_00002 2294 4 Skin 0.44 protein_coding missense_variant MODERATE 1268A>C Asn423Thr
M0007941 IKAEBCDM_00002 2296 4 Skin 0.44 protein_coding missense_variant MODERATE 1270T>G Phe424Val
M0007942 IKAEBCDM_00002 2676 4 Skin 0.44 protein_coding synonymous_variant LOW 1650A>G Thr550Thr
M0007943 IKAEBCDM_00002 2704 4 Skin 0.44 protein_coding missense_variant MODERATE 1678T>A Leu560Ile
M0007944 IKAEBCDM_00003 2983 4 Skin 0.44 protein_coding missense_variant MODERATE 28T>C Tyr10His
M0007945 IKAEBCDM_00003 2984 4 Skin 0.44 protein_coding missense_variant MODERATE 29A>C Tyr10Ser
M0007946 IKAEBCDM_00003 3082 4 Skin 0.44 protein_coding missense_variant MODERATE 127A>G Ser43Gly
M0007947 IKAEBCDM_00003 3107 4 Skin 0.44 protein_coding missense_variant MODERATE 152A>G Asp51Gly
M0007948 IKAEBCDM_00003 3127 4 Skin 0.44 protein_coding missense_variant MODERATE 172C>T Arg58Cys
M0007949 IKAEBCDM_00003 3130 4 Skin 0.44 protein_coding stop_gained HIGH 175G>T Glu59*
M0007950 IKAEBCDM_00001 3172 4 Skin 0.44 protein_coding downstream_gene_variant MODIFIER *2135G>T None
M0007951 IKAEBCDM_00001 3176 4 Skin 0.44 protein_coding downstream_gene_variant MODIFIER *2139G>A None
M0007952 IKAEBCDM_00004 3329 4 Skin 0.44 protein_coding missense_variant MODERATE 1903G>A Ala635Thr
M0007953 IKAEBCDM_00004 3408 4 Skin 0.44 protein_coding synonymous_variant LOW 1824A>G Ser608Ser
M0007954 IKAEBCDM_00004 3409 4 Skin 0.44 protein_coding missense_variant MODERATE 1823C>T Ser608Leu
M0007955 IKAEBCDM_00004 3435 4 Skin 0.44 protein_coding synonymous_variant LOW 1797A>G Gln599Gln
M0007956 IKAEBCDM_00004 3537 4 Skin 0.44 protein_coding missense_variant MODERATE 1695A>G Ile565Met
M0007957 IKAEBCDM_00004 3577 4 Skin 0.44 protein_coding missense_variant MODERATE 1655C>T Pro552Leu
M0007958 IKAEBCDM_00004 3648 4 Skin 0.44 protein_coding synonymous_variant LOW 1584A>T Ile528Ile
M0007959 IKAEBCDM_00004 4411 4 Skin 0.44 protein_coding missense_variant MODERATE 821T>C Val274Ala
M0007960 IKAEBCDM_00004 4679 4 Skin 0.44 protein_coding missense_variant MODERATE 553T>C Ser185Pro
M0007961 IKAEBCDM_00004 4979 4 Skin 0.44 protein_coding missense_variant MODERATE 253C>T Pro85Ser
M0007962 IKAEBCDM_00004 4991 4 Skin 0.44 protein_coding missense_variant MODERATE 241A>C Lys81Gln
M0007963 IKAEBCDM_00004 5024 4 Skin 0.44 protein_coding synonymous_variant LOW 208T>C Leu70Leu
M0007964 IKAEBCDM_00002 1348 3 Skin 0.33 protein_coding stop_gained HIGH 322C>T Gln108*
M0007965 IKAEBCDM_00002 1350 3 Skin 0.33 protein_coding missense_variant MODERATE 324A>T Gln108His
M0007966 IKAEBCDM_00002 1480 3 Skin 0.33 protein_coding missense_variant MODERATE 454A>G Thr152Ala
M0007967 IKAEBCDM_00002 1483 3 Skin 0.33 protein_coding synonymous_variant LOW 457T>C Leu153Leu
M0007968 IKAEBCDM_00002 1494 3 Skin 0.33 protein_coding synonymous_variant LOW 468C>T Thr156Thr
M0007969 IKAEBCDM_00002 2125 3 Skin 0.33 protein_coding missense_variant MODERATE 1099G>A Val367Met
M0007970 IKAEBCDM_00002 2144 3 Skin 0.33 protein_coding missense_variant MODERATE 1118A>G Asp373Gly
M0007971 IKAEBCDM_00002 2473 3 Skin 0.33 protein_coding missense_variant MODERATE 1447A>G Thr483Ala
M0007972 IKAEBCDM_00002 2527 3 Skin 0.33 protein_coding missense_variant MODERATE 1501G>A Asp501Asn
M0007973 IKAEBCDM_00002 2607 3 Skin 0.33 protein_coding synonymous_variant LOW 1581C>T Tyr527Tyr
M0007974 IKAEBCDM_00002 2764 3 Skin 0.33 protein_coding missense_variant MODERATE 1738G>A Ala580Thr
M0007975 IKAEBCDM_00002 2877 3 Skin 0.33 protein_coding synonymous_variant LOW 1851C>T His617His
M0007976 IKAEBCDM_00004 3969 3 Skin 0.33 protein_coding synonymous_variant LOW 1263C>T His421His
M0007977 IKAEBCDM_00004 3998 3 Skin 0.33 protein_coding missense_variant MODERATE 1234C>A Gln412Lys
M0007978 IKAEBCDM_00004 4279 3 Skin 0.33 protein_coding missense_variant MODERATE 953T>G Ile318Ser
M0007979 IKAEBCDM_00004 4332 3 Skin 0.33 protein_coding synonymous_variant LOW 900T>G Gly300Gly
M0007980 IKAEBCDM_00004 4594 3 Skin 0.33 protein_coding missense_variant MODERATE 638C>T Ala213Val
M0007981 IKAEBCDM_00004 4638 3 Skin 0.33 protein_coding synonymous_variant LOW 594A>G Gln198Gln
M0007982 IKAEBCDM_00004 4720 3 Skin 0.33 protein_coding missense_variant MODERATE 512A>G Asp171Gly
M0007983 IKAEBCDM_00004 4738 3 Skin 0.33 protein_coding missense_variant MODERATE 494T>C Ile165Thr
M0007984 IKAEBCDM_00004 4780 3 Skin 0.33 protein_coding missense_variant MODERATE 452T>C Val151Ala
M0007985 IKAEBCDM_00004 5105 3 Skin 0.33 protein_coding missense_variant MODERATE 127T>C Tyr43His






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition
IKAEBCDM_00004 VFG004752 Lipase 74.7 2.8e-282 1 668 1.0 0.9809 Exoenzyme glycerol ester hydrolase prediction







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term