Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1642
  Reference Plasmid   1111525849483863_bin.31__k141_349813
  Reference Plasmid Size   14640
  Reference Plasmid GC Content   0.68
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0009744 JGKJLGFG_00007 11881 3 Skin 0.27 protein_coding upstream_gene_variant MODIFIER -39T>C None
M0009745 JGKJLGFG_00007 11918 3 Skin 0.27 protein_coding upstream_gene_variant MODIFIER -76T>C None
M0009746 JGKJLGFG_00007 11931 3 Skin 0.27 protein_coding upstream_gene_variant MODIFIER -89A>C None
M0009747 JGKJLGFG_00007 11945 3 Skin 0.27 protein_coding upstream_gene_variant MODIFIER -103A>G None
M0009748 JGKJLGFG_00007 11993 3 Skin 0.27 protein_coding upstream_gene_variant MODIFIER -151C>A None
M0009749 JGKJLGFG_00008 12349 3 Skin 0.27 protein_coding synonymous_variant LOW 351A>G Gly117Gly
M0009750 JGKJLGFG_00008 13180 4 Skin 0.36 protein_coding synonymous_variant LOW 1182G>A Thr394Thr
M0009751 JGKJLGFG_00008 13183 4 Skin 0.36 protein_coding synonymous_variant LOW 1185G>A Lys395Lys
M0009752 JGKJLGFG_00008 13202 3 Skin 0.27 protein_coding missense_variant MODERATE 1204G>C Gly402Arg
M0009753 JGKJLGFG_00008 13222 3 Skin 0.27 protein_coding synonymous_variant LOW 1224G>A Ala408Ala
M0009754 JGKJLGFG_00008 13232 3 Skin 0.27 protein_coding missense_variant MODERATE 1234G>A Asp412Asn
M0009755 JGKJLGFG_00008 13283 3 Skin 0.27 protein_coding missense_variant MODERATE 1285A>G Thr429Ala
M0009756 JGKJLGFG_00008 13284 3 Skin 0.27 protein_coding missense_variant MODERATE 1286C>T Thr429Met
M0009757 JGKJLGFG_00008 13285 3 Skin 0.27 protein_coding synonymous_variant LOW 1287G>C Thr429Thr
M0009758 JGKJLGFG_00008 13290 4 Skin 0.36 protein_coding missense_variant MODERATE 1292G>A Arg431Lys
M0009759 JGKJLGFG_00008 13321 3 Skin 0.27 protein_coding synonymous_variant LOW 1323C>G Leu441Leu
M0009760 JGKJLGFG_00008 13340 4 Skin 0.36 protein_coding missense_variant MODERATE 1342C>A Arg448Ser
M0009761 JGKJLGFG_00008 13380 3 Skin 0.27 protein_coding missense_variant MODERATE 1382G>A Ser461Asn
M0009762 JGKJLGFG_00008 13538 4 Skin 0.36 protein_coding missense_variant MODERATE 1540T>G Leu514Val
M0009763 JGKJLGFG_00009 13916 5 Skin 0.45 protein_coding synonymous_variant LOW 27G>C Ala9Ala
M0009764 JGKJLGFG_00007 14107 6 Skin 0.55 protein_coding upstream_gene_variant MODIFIER -2265T>G None
M0009765 JGKJLGFG_00007 14138 6 Skin 0.55 protein_coding upstream_gene_variant MODIFIER -2296A>G None
M0009766 JGKJLGFG_00007 14369 7 Skin 0.64 protein_coding upstream_gene_variant MODIFIER -2527A>T None
M0009767 JGKJLGFG_00007 14410 5 Skin 0.45 protein_coding upstream_gene_variant MODIFIER -2568G>C None
M0009768 JGKJLGFG_00007 14487 7 Skin 0.64 protein_coding upstream_gene_variant MODIFIER -2645T>C None
M0009769 JGKJLGFG_00007 14506 5 Skin 0.45 protein_coding upstream_gene_variant MODIFIER -2664A>G None
M0009770 JGKJLGFG_00007 14526 7 Skin 0.64 protein_coding upstream_gene_variant MODIFIER -2684T>C None
M0009771 JGKJLGFG_00007 14580 7 Skin 0.64 protein_coding upstream_gene_variant MODIFIER -2738C>T None
M0009772 JGKJLGFG_00003 4120 3 Skin 0.27 protein_coding missense_variant MODERATE 646G>A Ala216Thr
M0009773 JGKJLGFG_00003 4819 3 Skin 0.27 protein_coding missense_variant MODERATE 1345C>T His449Tyr
M0009774 JGKJLGFG_00003 5385 3 Skin 0.27 protein_coding synonymous_variant LOW 1911A>G Lys637Lys
M0009775 JGKJLGFG_00003 5395 3 Skin 0.27 protein_coding missense_variant MODERATE 1921G>A Ala641Thr
M0009776 JGKJLGFG_00003 5443 3 Skin 0.27 protein_coding missense_variant MODERATE 1969C>A Gln657Lys
M0009777 JGKJLGFG_00003 5555 3 Skin 0.27 protein_coding missense_variant MODERATE 2081T>C Ile694Thr
M0009778 JGKJLGFG_00003 5567 3 Skin 0.27 protein_coding missense_variant MODERATE 2093C>T Pro698Leu
M0009779 JGKJLGFG_00008 13613 3 Skin 0.27 protein_coding missense_variant MODERATE 1615G>A Gly539Ser
M0009780 JGKJLGFG_00007 13771 3 Skin 0.27 protein_coding upstream_gene_variant MODIFIER -1929G>C None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term