Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1645
  Reference Plasmid   1111525849483863_bin.5__k141_1049385
  Reference Plasmid Size   19696
  Reference Plasmid GC Content   0.66
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0009790 GOMPDBLB_00012 15073 3 Skin 0.23 protein_coding synonymous_variant LOW 2214G>A Ser738Ser
M0009791 GOMPDBLB_00014 16579 3 Skin 0.23 protein_coding missense_variant MODERATE 89C>T Ala30Val
M0009792 GOMPDBLB_00015 17424 3 Skin 0.23 protein_coding missense_variant MODERATE 23C>A Thr8Asn
M0009793 GOMPDBLB_00015 17560 4 Skin 0.31 protein_coding synonymous_variant LOW 159T>C Leu53Leu
M0009794 GOMPDBLB_00015 17930 4 Skin 0.31 protein_coding synonymous_variant LOW 529C>A Arg177Arg
M0009795 GOMPDBLB_00015 17931 4 Skin 0.31 protein_coding missense_variant MODERATE 530G>A Arg177Gln
M0009796 GOMPDBLB_00015 17959 4 Skin 0.31 protein_coding synonymous_variant LOW 558T>C Asp186Asp
M0009797 GOMPDBLB_00015 18049 3 Skin 0.23 protein_coding synonymous_variant LOW 648G>A Ser216Ser
M0009798 GOMPDBLB_00015 18142 4 Skin 0.31 protein_coding synonymous_variant LOW 741C>T Gly247Gly
M0009799 GOMPDBLB_00016 18621 4 Skin 0.31 protein_coding synonymous_variant LOW 330A>G Val110Val
M0009800 GOMPDBLB_00016 18654 4 Skin 0.31 protein_coding synonymous_variant LOW 363T>C Val121Val
M0009801 GOMPDBLB_00016 18658 4 Skin 0.31 protein_coding synonymous_variant LOW 367T>C Leu123Leu
M0009802 GOMPDBLB_00016 18789 3 Skin 0.23 protein_coding synonymous_variant LOW 498C>G Thr166Thr
M0009803 GOMPDBLB_00016 18807 3 Skin 0.23 protein_coding synonymous_variant LOW 516T>C Ala172Ala
M0009804 GOMPDBLB_00016 18808 4 Skin 0.31 protein_coding synonymous_variant LOW 517C>T Leu173Leu
M0009805 GOMPDBLB_00016 18913 4 Skin 0.31 protein_coding missense_variant MODERATE 622A>G Thr208Ala
M0009806 GOMPDBLB_00016 19098 4 Skin 0.31 protein_coding synonymous_variant LOW 807T>C Tyr269Tyr
M0009807 GOMPDBLB_00012 19145 3 Skin 0.23 protein_coding downstream_gene_variant MODIFIER *4015T>C None
M0009808 GOMPDBLB_00012 19195 3 Skin 0.23 protein_coding downstream_gene_variant MODIFIER *4065G>A None
M0009809 GOMPDBLB_00012 19235 3 Skin 0.23 protein_coding downstream_gene_variant MODIFIER *4105G>C None
M0009810 GOMPDBLB_00001 355 3 Skin 0.23 protein_coding synonymous_variant LOW 339A>G Leu113Leu
M0009811 GOMPDBLB_00002 1051 3 Skin 0.23 protein_coding missense_variant MODERATE 1988C>G Pro663Arg
M0009812 GOMPDBLB_00002 1160 3 Skin 0.23 protein_coding missense_variant MODERATE 1879A>G Ile627Val
M0009813 GOMPDBLB_00002 1753 3 Skin 0.23 protein_coding missense_variant MODERATE 1286T>C Leu429Pro
M0009814 GOMPDBLB_00002 4066 3 Skin 0.23 protein_coding upstream_gene_variant MODIFIER -1028T>C None
M0009815 GOMPDBLB_00004 4092 3 Skin 0.23 protein_coding synonymous_variant LOW 1848C>G Ala616Ala
M0009816 GOMPDBLB_00004 4470 3 Skin 0.23 protein_coding synonymous_variant LOW 1470G>C Val490Val
M0009817 GOMPDBLB_00004 4563 3 Skin 0.23 protein_coding synonymous_variant LOW 1377G>A Glu459Glu
M0009818 GOMPDBLB_00004 4566 3 Skin 0.23 protein_coding synonymous_variant LOW 1374C>T Gly458Gly
M0009819 GOMPDBLB_00004 4653 3 Skin 0.23 protein_coding synonymous_variant LOW 1287A>G Val429Val
M0009820 GOMPDBLB_00014 16574 3 Skin 0.23 protein_coding synonymous_variant LOW 84G>A Pro28Pro
M0009821 GOMPDBLB_00015 17640 3 Skin 0.23 protein_coding missense_variant MODERATE 239G>A Arg80Lys
M0009822 GOMPDBLB_00015 17683 3 Skin 0.23 protein_coding synonymous_variant LOW 282T>C Ala94Ala
M0009823 GOMPDBLB_00016 18519 3 Skin 0.23 protein_coding synonymous_variant LOW 228T>C Pro76Pro
M0009824 GOMPDBLB_00002 8025 3 Skin 0.23 protein_coding upstream_gene_variant MODIFIER -4987C>G None
M0009825 GOMPDBLB_00003 8092 3 Skin 0.23 protein_coding upstream_gene_variant MODIFIER -4133G>C None
M0009826 GOMPDBLB_00003 8123 3 Skin 0.23 protein_coding upstream_gene_variant MODIFIER -4164G>T None
M0009827 GOMPDBLB_00008 8194 4 Skin 0.31 protein_coding synonymous_variant LOW 39T>C Tyr13Tyr
M0009828 GOMPDBLB_00008 8207 3 Skin 0.23 protein_coding missense_variant MODERATE 52C>A Arg18Ser
M0009829 GOMPDBLB_00008 8228 4 Skin 0.31 protein_coding missense_variant MODERATE 73C>T His25Tyr
M0009830 GOMPDBLB_00008 8323 4 Skin 0.31 protein_coding synonymous_variant LOW 168T>C Asp56Asp
M0009831 GOMPDBLB_00008 8389 3 Skin 0.23 protein_coding synonymous_variant LOW 234A>G Ala78Ala
M0009832 GOMPDBLB_00008 8401 3 Skin 0.23 protein_coding synonymous_variant LOW 246G>A Glu82Glu
M0009833 GOMPDBLB_00008 8472 3 Skin 0.23 protein_coding missense_variant MODERATE 317T>C Val106Ala
M0009834 GOMPDBLB_00008 8551 4 Skin 0.31 protein_coding synonymous_variant LOW 396G>A Pro132Pro
M0009835 GOMPDBLB_00008 8616 4 Skin 0.31 protein_coding missense_variant MODERATE 461G>A Arg154His
M0009836 GOMPDBLB_00004 9036 4 Skin 0.31 protein_coding upstream_gene_variant MODIFIER -3097G>A None
M0009837 GOMPDBLB_00009 9379 3 Skin 0.23 protein_coding missense_variant MODERATE 341A>G Lys114Arg
M0009838 GOMPDBLB_00009 9455 4 Skin 0.31 protein_coding synonymous_variant LOW 417G>C Ser139Ser
M0009839 GOMPDBLB_00009 9947 4 Skin 0.31 protein_coding synonymous_variant LOW 909T>C Arg303Arg
M0009840 GOMPDBLB_00009 9955 4 Skin 0.31 protein_coding missense_variant MODERATE 917G>A Arg306Gln
M0009841 GOMPDBLB_00009 9961 3 Skin 0.23 protein_coding missense_variant MODERATE 923A>G Lys308Arg
M0009842 GOMPDBLB_00008 8876 3 Skin 0.23 protein_coding missense_variant MODERATE 721T>C Tyr241His
M0009843 GOMPDBLB_00009 9356 3 Skin 0.23 protein_coding synonymous_variant LOW 318T>C His106His
M0009844 GOMPDBLB_00009 9635 3 Skin 0.23 protein_coding synonymous_variant LOW 597T>C Pro199Pro
M0009845 GOMPDBLB_00010 10507 4 Skin 0.31 protein_coding synonymous_variant LOW 174T>C Gly58Gly
M0009846 GOMPDBLB_00010 10762 4 Skin 0.31 protein_coding missense_variant MODERATE 429A>C Gln143His
M0009847 GOMPDBLB_00010 11041 3 Skin 0.23 protein_coding synonymous_variant LOW 708A>G Val236Val
M0009848 GOMPDBLB_00011 11417 4 Skin 0.31 protein_coding synonymous_variant LOW 78C>G Leu26Leu
M0009849 GOMPDBLB_00011 11486 4 Skin 0.31 protein_coding synonymous_variant LOW 147G>C Ala49Ala
M0009850 GOMPDBLB_00011 11795 4 Skin 0.31 protein_coding synonymous_variant LOW 456A>G Ala152Ala
M0009851 GOMPDBLB_00011 11825 4 Skin 0.31 protein_coding synonymous_variant LOW 486A>G Leu162Leu
M0009852 GOMPDBLB_00011 11947 4 Skin 0.31 protein_coding missense_variant MODERATE 608A>C Glu203Ala
M0009853 GOMPDBLB_00011 11948 4 Skin 0.31 protein_coding missense_variant MODERATE 609A>C Glu203Asp
M0009854 GOMPDBLB_00011 12379 3 Skin 0.23 protein_coding missense_variant MODERATE 1040T>G Leu347Arg
M0009855 GOMPDBLB_00011 12647 3 Skin 0.23 protein_coding synonymous_variant LOW 1308A>T Leu436Leu
M0009856 GOMPDBLB_00011 12753 4 Skin 0.31 protein_coding missense_variant MODERATE 1414T>C Phe472Leu
M0009857 GOMPDBLB_00011 12754 4 Skin 0.31 protein_coding missense_variant MODERATE 1415T>G Phe472Cys
M0009858 GOMPDBLB_00007 12778 4 Skin 0.31 protein_coding upstream_gene_variant MODIFIER -4837A>T None
M0009859 GOMPDBLB_00007 12810 4 Skin 0.31 protein_coding upstream_gene_variant MODIFIER -4869A>T None
M0009860 GOMPDBLB_00012 12872 3 Skin 0.23 protein_coding missense_variant MODERATE 13T>C Phe5Leu
M0009861 GOMPDBLB_00012 12875 3 Skin 0.23 protein_coding missense_variant MODERATE 16A>T Thr6Ser
M0009862 GOMPDBLB_00012 13520 4 Skin 0.31 protein_coding missense_variant MODERATE 661A>G Thr221Ala
M0009863 GOMPDBLB_00012 13559 4 Skin 0.31 protein_coding missense_variant MODERATE 700G>A Ala234Thr
M0009864 GOMPDBLB_00012 13699 3 Skin 0.23 protein_coding synonymous_variant LOW 840G>A Thr280Thr
M0009865 GOMPDBLB_00012 13723 4 Skin 0.31 protein_coding synonymous_variant LOW 864T>G Leu288Leu
M0009866 GOMPDBLB_00012 13735 3 Skin 0.23 protein_coding synonymous_variant LOW 876C>T Phe292Phe
M0009867 GOMPDBLB_00012 13779 4 Skin 0.31 protein_coding missense_variant MODERATE 920A>G Lys307Arg






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
GOMPDBLB_00012 QLG10512.1|CBM0 72 0 1 756 1 1
GOMPDBLB_00016 ASN82541.1|CE14 81.8 5.69e-160 1 275 0.9964 0.9964





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term