Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1649
  Reference Plasmid   1111525849483863_bin.5__k141_318451
  Reference Plasmid Size   21970
  Reference Plasmid GC Content   0.60
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0009893 IPGAINHB_00002 2486 4 Skin 0.33 protein_coding synonymous_variant LOW 48A>G Arg16Arg
M0009894 IPGAINHB_00004 3526 3 Skin 0.25 protein_coding synonymous_variant LOW 876G>A Thr292Thr
M0009895 IPGAINHB_00004 3586 3 Skin 0.25 protein_coding synonymous_variant LOW 816A>G Ala272Ala
M0009896 IPGAINHB_00004 4172 3 Skin 0.25 protein_coding missense_variant MODERATE 230A>G Asn77Ser
M0009897 IPGAINHB_00003 8223 3 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -4735T>G None
M0009898 IPGAINHB_00008 8866 3 Skin 0.25 protein_coding synonymous_variant LOW 591G>A Gly197Gly
M0009899 IPGAINHB_00009 9297 4 Skin 0.33 protein_coding synonymous_variant LOW 3096A>G Val1032Val
M0009900 IPGAINHB_00009 9525 4 Skin 0.33 protein_coding synonymous_variant LOW 2868C>A Gly956Gly
M0009901 IPGAINHB_00009 9543 4 Skin 0.33 protein_coding synonymous_variant LOW 2850T>C Gly950Gly
M0009902 IPGAINHB_00009 10698 3 Skin 0.25 protein_coding synonymous_variant LOW 1695C>T Ala565Ala
M0009903 IPGAINHB_00009 10766 3 Skin 0.25 protein_coding missense_variant MODERATE 1627G>A Val543Ile
M0009904 IPGAINHB_00009 10767 4 Skin 0.33 protein_coding synonymous_variant LOW 1626C>T Asp542Asp
M0009905 IPGAINHB_00009 10844 4 Skin 0.33 protein_coding missense_variant MODERATE 1549A>G Thr517Ala
M0009906 IPGAINHB_00009 10911 3 Skin 0.25 protein_coding synonymous_variant LOW 1482C>G Leu494Leu
M0009907 IPGAINHB_00009 11133 6 Skin 0.50 protein_coding synonymous_variant LOW 1260C>A Gly420Gly
M0009908 IPGAINHB_00009 11258 3 Skin 0.25 protein_coding missense_variant MODERATE 1135C>A His379Asn
M0009909 IPGAINHB_00009 11430 4 Skin 0.33 protein_coding synonymous_variant LOW 963A>G Arg321Arg
M0009910 IPGAINHB_00009 11622 3 Skin 0.25 protein_coding synonymous_variant LOW 771T>A Pro257Pro
M0009911 IPGAINHB_00009 11789 4 Skin 0.33 protein_coding missense_variant MODERATE 604A>G Thr202Ala
M0009912 IPGAINHB_00011 13449 3 Skin 0.25 protein_coding missense_variant MODERATE 430A>G Ser144Gly
M0009913 IPGAINHB_00011 13458 3 Skin 0.25 protein_coding missense_variant MODERATE 421A>G Thr141Ala
M0009914 IPGAINHB_00001 854 3 Skin 0.25 protein_coding missense_variant MODERATE 664G>A Glu222Lys
M0009915 IPGAINHB_00001 918 3 Skin 0.25 protein_coding synonymous_variant LOW 600T>C His200His
M0009916 IPGAINHB_00001 1293 3 Skin 0.25 protein_coding synonymous_variant LOW 225C>A Ala75Ala
M0009917 IPGAINHB_00002 1985 3 Skin 0.25 protein_coding synonymous_variant LOW 549C>G Leu183Leu
M0009918 IPGAINHB_00003 2684 3 Skin 0.25 protein_coding synonymous_variant LOW 805C>T Leu269Leu
M0009919 IPGAINHB_00002 6977 3 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -4444G>A None
M0009920 IPGAINHB_00007 7036 4 Skin 0.33 protein_coding missense_variant MODERATE 701C>G Thr234Ser
M0009921 IPGAINHB_00007 7137 3 Skin 0.25 protein_coding synonymous_variant LOW 600G>A Gln200Gln
M0009922 IPGAINHB_00007 7418 3 Skin 0.25 protein_coding missense_variant MODERATE 319A>G Ile107Val
M0009923 IPGAINHB_00009 9886 3 Skin 0.25 protein_coding missense_variant MODERATE 2507C>T Pro836Leu
M0009924 IPGAINHB_00009 10179 3 Skin 0.25 protein_coding synonymous_variant LOW 2214G>A Ala738Ala
M0009925 IPGAINHB_00009 10346 4 Skin 0.33 protein_coding missense_variant MODERATE 2047C>A Gln683Lys
M0009926 IPGAINHB_00009 10347 4 Skin 0.33 protein_coding synonymous_variant LOW 2046G>A Val682Val
M0009927 IPGAINHB_00009 10377 4 Skin 0.33 protein_coding missense_variant MODERATE 2016A>G Ile672Met
M0009928 IPGAINHB_00009 11115 3 Skin 0.25 protein_coding synonymous_variant LOW 1278G>A Val426Val






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term