Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1650
  Reference Plasmid   1111525849483863_bin.5__k141_449555
  Reference Plasmid Size   6132
  Reference Plasmid GC Content   0.61
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0009929 LFNDADHA_00003 1240 3 Skin 0.60 protein_coding synonymous_variant LOW 255G>C Arg85Arg
M0009930 LFNDADHA_00003 1324 3 Skin 0.60 protein_coding synonymous_variant LOW 339A>G Lys113Lys
M0009931 LFNDADHA_00003 1438 3 Skin 0.60 protein_coding synonymous_variant LOW 453T>C Phe151Phe
M0009932 LFNDADHA_00004 1866 3 Skin 0.60 protein_coding synonymous_variant LOW 156C>T Asn52Asn
M0009933 LFNDADHA_00003 1657 3 Skin 0.60 protein_coding synonymous_variant LOW 672C>G Leu224Leu
M0009934 LFNDADHA_00003 1662 4 Skin 0.80 protein_coding missense_variant MODERATE 677C>A Ala226Asp
M0009935 LFNDADHA_00004 1740 4 Skin 0.80 protein_coding synonymous_variant LOW 30G>A Gln10Gln
M0009936 LFNDADHA_00005 2270 3 Skin 0.60 protein_coding synonymous_variant LOW 384G>C Thr128Thr
M0009937 LFNDADHA_00005 2277 3 Skin 0.60 protein_coding missense_variant MODERATE 377T>C Ile126Thr
M0009938 LFNDADHA_00005 2354 4 Skin 0.80 protein_coding synonymous_variant LOW 300G>C Ala100Ala
M0009939 LFNDADHA_00001 1681 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -1330A>G None
M0009940 LFNDADHA_00001 1938 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -1587C>T None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term