Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1652
  Reference Plasmid   1111525849483863_bin.5__k141_984226
  Reference Plasmid Size   18213
  Reference Plasmid GC Content   0.65
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0010024 HDOAILAD_00005 2636 3 Skin 0.30 protein_coding synonymous_variant LOW 66C>G Ala22Ala
M0010025 HDOAILAD_00007 3320 3 Skin 0.30 protein_coding missense_variant MODERATE 815T>C Ile272Thr
M0010026 HDOAILAD_00007 3498 4 Skin 0.40 protein_coding missense_variant MODERATE 637G>A Val213Ile
M0010027 HDOAILAD_00002 4138 4 Skin 0.40 protein_coding upstream_gene_variant MODIFIER -3316A>G None
M0010028 HDOAILAD_00002 4193 4 Skin 0.40 protein_coding upstream_gene_variant MODIFIER -3371T>C None
M0010029 HDOAILAD_00008 4331 4 Skin 0.40 protein_coding missense_variant MODERATE 493A>C Thr165Pro
M0010030 HDOAILAD_00008 4439 3 Skin 0.30 protein_coding synonymous_variant LOW 385C>A Arg129Arg
M0010031 HDOAILAD_00008 4733 3 Skin 0.30 protein_coding synonymous_variant LOW 91T>C Leu31Leu
M0010032 HDOAILAD_00002 5298 3 Skin 0.30 protein_coding upstream_gene_variant MODIFIER -4476C>T None
M0010033 HDOAILAD_00002 5377 3 Skin 0.30 protein_coding upstream_gene_variant MODIFIER -4555G>A None
M0010034 HDOAILAD_00002 5378 3 Skin 0.30 protein_coding upstream_gene_variant MODIFIER -4556G>A None
M0010035 HDOAILAD_00010 6704 3 Skin 0.30 protein_coding synonymous_variant LOW 1098G>T Gly366Gly
M0010036 HDOAILAD_00011 7268 3 Skin 0.30 protein_coding synonymous_variant LOW 399A>C Gly133Gly
M0010037 HDOAILAD_00012 7902 4 Skin 0.40 protein_coding synonymous_variant LOW 15T>C Thr5Thr
M0010038 HDOAILAD_00012 7944 3 Skin 0.30 protein_coding synonymous_variant LOW 57A>G Leu19Leu
M0010039 HDOAILAD_00012 7953 3 Skin 0.30 protein_coding missense_variant MODERATE 66G>T Leu22Phe
M0010040 HDOAILAD_00012 7974 3 Skin 0.30 protein_coding missense_variant MODERATE 87C>G Ile29Met
M0010041 HDOAILAD_00013 9007 3 Skin 0.30 protein_coding synonymous_variant LOW 159T>G Pro53Pro
M0010042 HDOAILAD_00013 9436 3 Skin 0.30 protein_coding synonymous_variant LOW 588G>C Val196Val
M0010043 HDOAILAD_00014 10189 4 Skin 0.40 protein_coding missense_variant MODERATE 548G>A Arg183Gln
M0010044 HDOAILAD_00015 10438 4 Skin 0.40 protein_coding synonymous_variant LOW 57A>G Val19Val
M0010045 HDOAILAD_00015 10497 5 Skin 0.50 protein_coding missense_variant MODERATE 116G>A Arg39Gln
M0010046 HDOAILAD_00015 10657 3 Skin 0.30 protein_coding synonymous_variant LOW 276C>T Asp92Asp
M0010047 HDOAILAD_00015 10687 3 Skin 0.30 protein_coding synonymous_variant LOW 306C>G Ala102Ala
M0010048 HDOAILAD_00015 10744 3 Skin 0.30 protein_coding missense_variant MODERATE 363G>C Lys121Asn
M0010049 HDOAILAD_00015 10813 4 Skin 0.40 protein_coding synonymous_variant LOW 432A>C Gly144Gly
M0010050 HDOAILAD_00015 10816 4 Skin 0.40 protein_coding synonymous_variant LOW 435A>G Lys145Lys
M0010051 HDOAILAD_00015 11155 4 Skin 0.40 protein_coding synonymous_variant LOW 774A>C Arg258Arg
M0010052 HDOAILAD_00015 11526 3 Skin 0.30 protein_coding missense_variant MODERATE 1145G>A Cys382Tyr
M0010053 HDOAILAD_00015 11581 3 Skin 0.30 protein_coding synonymous_variant LOW 1200C>T Asp400Asp
M0010054 HDOAILAD_00015 11586 5 Skin 0.50 protein_coding missense_variant MODERATE 1205T>C Leu402Pro
M0010055 HDOAILAD_00015 11605 5 Skin 0.50 protein_coding synonymous_variant LOW 1224A>T Arg408Arg
M0010056 HDOAILAD_00018 11643 5 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -3539G>A None
M0010057 HDOAILAD_00016 11692 3 Skin 0.30 protein_coding missense_variant MODERATE 1732C>G Leu578Val
M0010058 HDOAILAD_00016 11925 5 Skin 0.50 protein_coding missense_variant MODERATE 1499T>A Leu500His
M0010059 HDOAILAD_00016 12119 3 Skin 0.30 protein_coding missense_variant MODERATE 1305G>C Gln435His
M0010060 HDOAILAD_00016 12283 3 Skin 0.30 protein_coding missense_variant MODERATE 1141G>C Ala381Pro
M0010061 HDOAILAD_00016 12418 3 Skin 0.30 protein_coding missense_variant MODERATE 1006C>G Gln336Glu
M0010062 HDOAILAD_00016 12455 5 Skin 0.50 protein_coding synonymous_variant LOW 969C>T Ser323Ser
M0010063 HDOAILAD_00016 12623 4 Skin 0.40 protein_coding missense_variant MODERATE 801G>C Glu267Asp
M0010064 HDOAILAD_00016 12699 6 Skin 0.60 protein_coding missense_variant MODERATE 725A>G Gln242Arg
M0010065 HDOAILAD_00016 12852 6 Skin 0.60 protein_coding missense_variant MODERATE 572A>C Asn191Thr
M0010066 HDOAILAD_00016 12937 3 Skin 0.30 protein_coding missense_variant MODERATE 487G>A Val163Ile
M0010067 HDOAILAD_00016 12962 5 Skin 0.50 protein_coding synonymous_variant LOW 462G>C Pro154Pro
M0010068 HDOAILAD_00016 13130 6 Skin 0.60 protein_coding synonymous_variant LOW 294C>T Arg98Arg
M0010069 HDOAILAD_00016 13247 6 Skin 0.60 protein_coding missense_variant MODERATE 177A>G Ile59Met
M0010070 HDOAILAD_00016 13429 4 Skin 0.40 protein_coding upstream_gene_variant MODIFIER -6G>A None
M0010071 HDOAILAD_00016 13430 5 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -7G>A None
M0010072 HDOAILAD_00017 13842 7 Skin 0.70 protein_coding missense_variant MODERATE 1158A>C Glu386Asp
M0010073 HDOAILAD_00017 14178 5 Skin 0.50 protein_coding synonymous_variant LOW 822G>C Pro274Pro
M0010074 HDOAILAD_00017 14451 5 Skin 0.50 protein_coding synonymous_variant LOW 549G>A Gly183Gly
M0010075 HDOAILAD_00017 14751 7 Skin 0.70 protein_coding synonymous_variant LOW 249T>C Asn83Asn
M0010076 HDOAILAD_00017 14934 5 Skin 0.50 protein_coding synonymous_variant LOW 66G>A Val22Val
M0010077 HDOAILAD_00016 15157 3 Skin 0.30 protein_coding upstream_gene_variant MODIFIER -1734A>G None
M0010078 HDOAILAD_00018 15283 4 Skin 0.40 protein_coding missense_variant MODERATE 102C>G His34Gln
M0010079 HDOAILAD_00018 15343 5 Skin 0.50 protein_coding synonymous_variant LOW 162T>C Ser54Ser
M0010080 HDOAILAD_00018 15616 5 Skin 0.50 protein_coding synonymous_variant LOW 435G>C Leu145Leu
M0010081 HDOAILAD_00018 15617 5 Skin 0.50 protein_coding synonymous_variant LOW 436C>T Leu146Leu
M0010082 HDOAILAD_00018 15657 3 Skin 0.30 protein_coding missense_variant MODERATE 476C>T Ala159Val
M0010083 HDOAILAD_00016 15733 4 Skin 0.40 protein_coding upstream_gene_variant MODIFIER -2310A>G None
M0010084 HDOAILAD_00019 16133 4 Skin 0.40 protein_coding synonymous_variant LOW 372C>G Thr124Thr
M0010085 HDOAILAD_00019 16175 4 Skin 0.40 protein_coding synonymous_variant LOW 414T>C Gly138Gly
M0010086 HDOAILAD_00019 16580 5 Skin 0.50 protein_coding synonymous_variant LOW 819C>T His273His
M0010087 HDOAILAD_00019 16787 5 Skin 0.50 protein_coding synonymous_variant LOW 1026T>C Ser342Ser
M0010088 HDOAILAD_00020 16933 5 Skin 0.50 protein_coding synonymous_variant LOW 6T>C Pro2Pro
M0010089 HDOAILAD_00020 17214 3 Skin 0.30 protein_coding missense_variant MODERATE 287A>G Glu96Gly
M0010090 HDOAILAD_00021 17617 3 Skin 0.30 protein_coding missense_variant MODERATE 178C>A Leu60Met
M0010091 HDOAILAD_00021 17725 4 Skin 0.40 protein_coding missense_variant MODERATE 286A>C Lys96Gln
M0010092 HDOAILAD_00017 14754 3 Skin 0.30 protein_coding synonymous_variant LOW 246C>T Phe82Phe
M0010093 HDOAILAD_00018 15328 4 Skin 0.40 protein_coding synonymous_variant LOW 147T>C Gly49Gly
M0010094 HDOAILAD_00018 15662 3 Skin 0.30 protein_coding missense_variant MODERATE 481G>A Glu161Lys
M0010095 HDOAILAD_00018 15666 3 Skin 0.30 protein_coding missense_variant MODERATE 485C>A Ala162Asp
M0010096 HDOAILAD_00019 16370 3 Skin 0.30 protein_coding synonymous_variant LOW 609C>G Ala203Ala
M0010097 HDOAILAD_00016 15014 3 Skin 0.30 protein_coding upstream_gene_variant MODIFIER -1591C>A None
M0010098 HDOAILAD_00016 15016 3 Skin 0.30 protein_coding upstream_gene_variant MODIFIER -1593T>C None
M0010099 HDOAILAD_00012 7909 3 Skin 0.30 protein_coding missense_variant MODERATE 22G>C Val8Leu
M0010100 HDOAILAD_00016 12521 3 Skin 0.30 protein_coding synonymous_variant LOW 903A>C Pro301Pro






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term