Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1660
  Reference Plasmid   1111525849485004_bin.26__k141_417633
  Reference Plasmid Size   4746
  Reference Plasmid GC Content   0.38
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0010247 ANLKGOII_00002 1925 4 Skin 0.67 protein_coding missense_variant MODERATE 707C>A Ala236Glu
M0010248 ANLKGOII_00002 2247 4 Skin 0.67 protein_coding synonymous_variant LOW 1029A>G Arg343Arg
M0010249 ANLKGOII_00002 2646 3 Skin 0.50 protein_coding missense_variant MODERATE 1428T>G His476Gln
M0010250 ANLKGOII_00002 2749 4 Skin 0.67 protein_coding missense_variant MODERATE 1531G>T Val511Leu
M0010251 ANLKGOII_00002 2885 4 Skin 0.67 protein_coding missense_variant MODERATE 1667C>T Ser556Leu
M0010252 ANLKGOII_00002 2952 4 Skin 0.67 protein_coding synonymous_variant LOW 1734T>C Ile578Ile
M0010253 ANLKGOII_00002 3003 4 Skin 0.67 protein_coding synonymous_variant LOW 1785T>C Ala595Ala
M0010254 ANLKGOII_00002 3112 4 Skin 0.67 protein_coding missense_variant MODERATE 1894C>A Gln632Lys
M0010255 ANLKGOII_00002 3113 4 Skin 0.67 protein_coding missense_variant MODERATE 1895A>T Gln632Leu
M0010256 ANLKGOII_00002 3143 4 Skin 0.67 protein_coding missense_variant MODERATE 1925T>C Leu642Ser
M0010257 ANLKGOII_00002 3153 4 Skin 0.67 protein_coding synonymous_variant LOW 1935C>T Phe645Phe
M0010258 ANLKGOII_00003 3447 4 Skin 0.67 protein_coding missense_variant MODERATE 212T>A Val71Asp
M0010259 ANLKGOII_00003 3574 4 Skin 0.67 protein_coding synonymous_variant LOW 339A>G Arg113Arg
M0010260 ANLKGOII_00003 3796 4 Skin 0.67 protein_coding synonymous_variant LOW 561T>C Ile187Ile
M0010261 ANLKGOII_00001 4079 3 Skin 0.50 protein_coding downstream_gene_variant MODIFIER *2963C>T None
M0010262 ANLKGOII_00001 4105 4 Skin 0.67 protein_coding downstream_gene_variant MODIFIER *2989G>A None
M0010263 ANLKGOII_00001 582 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -238C>A None
M0010264 ANLKGOII_00002 1631 3 Skin 0.50 protein_coding missense_variant MODERATE 413C>T Thr138Ile
M0010265 ANLKGOII_00002 1755 3 Skin 0.50 protein_coding synonymous_variant LOW 537T>G Arg179Arg
M0010266 ANLKGOII_00002 1936 3 Skin 0.50 protein_coding missense_variant MODERATE 718T>A Cys240Ser
M0010267 ANLKGOII_00002 2586 3 Skin 0.50 protein_coding missense_variant MODERATE 1368A>G Ile456Met
M0010268 ANLKGOII_00003 3301 3 Skin 0.50 protein_coding missense_variant MODERATE 66A>G Ile22Met
M0010269 ANLKGOII_00003 3606 3 Skin 0.50 protein_coding missense_variant MODERATE 371C>A Ala124Asp
M0010270 ANLKGOII_00001 4141 3 Skin 0.50 protein_coding downstream_gene_variant MODIFIER *3025A>G None
M0010271 ANLKGOII_00001 4146 3 Skin 0.50 protein_coding downstream_gene_variant MODIFIER *3030T>G None
M0010272 ANLKGOII_00004 4371 3 Skin 0.50 protein_coding missense_variant MODERATE 226G>A Val76Ile
M0010273 ANLKGOII_00004 4390 3 Skin 0.50 protein_coding synonymous_variant LOW 207G>A Glu69Glu
M0010274 ANLKGOII_00004 4489 3 Skin 0.50 protein_coding synonymous_variant LOW 108T>C Leu36Leu
M0010275 ANLKGOII_00004 4492 3 Skin 0.50 protein_coding synonymous_variant LOW 105A>C Ala35Ala
M0010276 ANLKGOII_00004 4498 3 Skin 0.50 protein_coding synonymous_variant LOW 99C>T Asp33Asp
M0010277 ANLKGOII_00004 4504 3 Skin 0.50 protein_coding synonymous_variant LOW 93G>A Gly31Gly
M0010278 ANLKGOII_00004 4552 3 Skin 0.50 protein_coding synonymous_variant LOW 45A>T Gly15Gly
M0010279 ANLKGOII_00004 4555 3 Skin 0.50 protein_coding synonymous_variant LOW 42G>A Glu14Glu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term