Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1668
  Reference Plasmid   1111525849486442_bin.27__k141_113993
  Reference Plasmid Size   13885
  Reference Plasmid GC Content   0.57
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0010445 NNMAJDIB_00004 3224 22 Skin 0.71 protein_coding stop_lost&splice_region_variant HIGH 289T>C Ter97Glnext*?
M0010446 NNMAJDIB_00013 9797 9 Skin 0.29 protein_coding missense_variant MODERATE 194A>C Lys65Thr
M0010447 NNMAJDIB_00015 12165 6 Skin 0.19 protein_coding synonymous_variant LOW 801G>A Pro267Pro
M0010448 NNMAJDIB_00015 12189 6 Skin 0.19 protein_coding synonymous_variant LOW 825T>C Ala275Ala
M0010449 NNMAJDIB_00006 4433 20 Skin 0.65 protein_coding synonymous_variant LOW 696G>A Val232Val
M0010450 NNMAJDIB_00008 5471 5 Skin 0.16 protein_coding synonymous_variant LOW 28C>T Leu10Leu
M0010451 NNMAJDIB_00008 5713 5 Skin 0.16 protein_coding synonymous_variant LOW 270C>A Ala90Ala
M0010452 NNMAJDIB_00008 5509 4 Skin 0.13 protein_coding synonymous_variant LOW 66A>G Ala22Ala
M0010453 NNMAJDIB_00008 5518 4 Skin 0.13 protein_coding synonymous_variant LOW 75G>A Glu25Glu
M0010454 NNMAJDIB_00008 5524 4 Skin 0.13 protein_coding synonymous_variant LOW 81T>G Pro27Pro
M0010455 NNMAJDIB_00008 5542 4 Skin 0.13 protein_coding synonymous_variant LOW 99A>G Lys33Lys
M0010456 NNMAJDIB_00008 5548 4 Skin 0.13 protein_coding synonymous_variant LOW 105A>G Pro35Pro
M0010457 NNMAJDIB_00008 5551 4 Skin 0.13 protein_coding synonymous_variant LOW 108G>A Val36Val
M0010458 NNMAJDIB_00008 5563 4 Skin 0.13 protein_coding synonymous_variant LOW 120G>A Lys40Lys
M0010459 NNMAJDIB_00008 5587 4 Skin 0.13 protein_coding synonymous_variant LOW 144C>T Asn48Asn
M0010460 NNMAJDIB_00008 5617 4 Skin 0.13 protein_coding synonymous_variant LOW 174A>G Glu58Glu
M0010461 NNMAJDIB_00008 5629 4 Skin 0.13 protein_coding synonymous_variant LOW 186C>T Ser62Ser
M0010462 NNMAJDIB_00008 5632 4 Skin 0.13 protein_coding synonymous_variant LOW 189C>T Gly63Gly
M0010463 NNMAJDIB_00008 5638 4 Skin 0.13 protein_coding synonymous_variant LOW 195C>G Thr65Thr
M0010464 NNMAJDIB_00008 5639 4 Skin 0.13 protein_coding synonymous_variant LOW 196T>C Leu66Leu
M0010465 NNMAJDIB_00008 5653 4 Skin 0.13 protein_coding synonymous_variant LOW 210C>T Ile70Ile
M0010466 NNMAJDIB_00008 5679 4 Skin 0.13 protein_coding missense_variant MODERATE 236C>T Ala79Val
M0010467 NNMAJDIB_00008 5680 4 Skin 0.13 protein_coding synonymous_variant LOW 237C>T Ala79Ala
M0010468 NNMAJDIB_00008 5719 4 Skin 0.13 protein_coding synonymous_variant LOW 276C>T Ala92Ala
M0010469 NNMAJDIB_00008 5737 4 Skin 0.13 protein_coding synonymous_variant LOW 294A>G Pro98Pro
M0010470 NNMAJDIB_00008 5755 4 Skin 0.13 protein_coding synonymous_variant LOW 312G>C Arg104Arg






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group
NNMAJDIB_00007 Palmitic acid [class: Free Fatty Acids] 98 3.1e-77 1 150 1.0000 0.9317 prediction






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
NNMAJDIB_00015 2.A.1.14.9 79.9 5.6e-213 1 456 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)