Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1670
  Reference Plasmid   1111525849486442_bin.27__k141_246620
  Reference Plasmid Size   50222
  Reference Plasmid GC Content   0.55
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0010484 FOBNIOOF_00022 25811 13 Skin 0.20 protein_coding missense_variant MODERATE 842A>G His281Arg
M0010485 FOBNIOOF_00024 28803 10 Skin 0.15 protein_coding synonymous_variant LOW 666A>G Leu222Leu
M0010486 FOBNIOOF_00033 39806 3 Skin 0.05 protein_coding synonymous_variant LOW 1011T>C Asn337Asn
M0010487 FOBNIOOF_00035 41698 4 Skin 0.06 protein_coding synonymous_variant LOW 657T>G Val219Val
M0010488 FOBNIOOF_00035 41788 3 Skin 0.05 protein_coding synonymous_variant LOW 747C>T Ala249Ala
M0010489 FOBNIOOF_00037 41799 4 Skin 0.06 protein_coding upstream_gene_variant MODIFIER -501T>C None
M0010490 FOBNIOOF_00039 43299 3 Skin 0.05 protein_coding synonymous_variant LOW 1299A>G Leu433Leu
M0010491 FOBNIOOF_00042 47732 3 Skin 0.05 protein_coding synonymous_variant LOW 489G>C Val163Val
M0010492 FOBNIOOF_00043 48724 4 Skin 0.06 protein_coding missense_variant MODERATE 547C>T Pro183Ser
M0010493 FOBNIOOF_00039 49512 7 Skin 0.11 protein_coding upstream_gene_variant MODIFIER -4915T>C None
M0010494 FOBNIOOF_00039 49518 7 Skin 0.11 protein_coding upstream_gene_variant MODIFIER -4921T>C None
M0010495 FOBNIOOF_00039 49527 7 Skin 0.11 protein_coding upstream_gene_variant MODIFIER -4930A>G None
M0010496 FOBNIOOF_00039 49530 7 Skin 0.11 protein_coding upstream_gene_variant MODIFIER -4933G>A None
M0010497 FOBNIOOF_00039 49534 7 Skin 0.11 protein_coding upstream_gene_variant MODIFIER -4937G>A None
M0010498 FOBNIOOF_00039 49536 7 Skin 0.11 protein_coding upstream_gene_variant MODIFIER -4939T>C None
M0010499 FOBNIOOF_00025 30527 4 Skin 0.06 protein_coding missense_variant MODERATE 959T>C Val320Ala
M0010500 FOBNIOOF_00035 41125 3 Skin 0.05 protein_coding synonymous_variant LOW 84A>T Ile28Ile
M0010501 FOBNIOOF_00043 48827 5 Skin 0.08 protein_coding synonymous_variant LOW 444C>T Val148Val
M0010502 FOBNIOOF_00043 49037 4 Skin 0.06 protein_coding synonymous_variant LOW 234C>T Gly78Gly






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant
FOBNIOOF_00032 PHI:8006 fecA 74.2 0 9 773 0.9897 0.9742 even-toed ungulates bovine mastitis ferric citrate outer membrane transporter reduced virulence






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
FOBNIOOF_00009 QQX53110.1|GH1 95.3 0 1 470 0.9979 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
FOBNIOOF_00032 1.B.14.1.20 74.2 0 9 773 0.9897 0.9742 1 Channels/Pores 1.B β-Barrel Porins 1.B.14 The Outer Membrane Receptor (OMR) Family
FOBNIOOF_00036 2.A.7.26.1 82.9 1e-43 1 105 0.9722 0.9722 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.7 The Drug/Metabolite Transporter (DMT) Superfamily