Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1674
  Reference Plasmid   1111525849486442_bin.45__k141_134390
  Reference Plasmid Size   14041
  Reference Plasmid GC Content   0.38
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0010516 DMMCPGNC_00005 4826 3 Skin 0.16 protein_coding synonymous_variant LOW 834C>T His278His
M0010517 DMMCPGNC_00005 4877 3 Skin 0.16 protein_coding synonymous_variant LOW 885T>C His295His
M0010518 DMMCPGNC_00005 5255 3 Skin 0.16 protein_coding synonymous_variant LOW 1263A>G Gly421Gly
M0010519 DMMCPGNC_00005 5273 3 Skin 0.16 protein_coding synonymous_variant LOW 1281G>A Val427Val
M0010520 DMMCPGNC_00005 5333 3 Skin 0.16 protein_coding synonymous_variant LOW 1341A>G Thr447Thr
M0010521 DMMCPGNC_00001 5445 5 Skin 0.26 protein_coding upstream_gene_variant MODIFIER -4793A>C None
M0010522 DMMCPGNC_00001 5448 5 Skin 0.26 protein_coding upstream_gene_variant MODIFIER -4796A>C None
M0010523 DMMCPGNC_00001 5449 5 Skin 0.26 protein_coding upstream_gene_variant MODIFIER -4797C>T None
M0010524 DMMCPGNC_00001 5490 5 Skin 0.26 protein_coding upstream_gene_variant MODIFIER -4838C>T None
M0010525 DMMCPGNC_00007 6116 3 Skin 0.16 protein_coding synonymous_variant LOW 720A>G Ala240Ala
M0010526 DMMCPGNC_00007 6176 4 Skin 0.21 protein_coding synonymous_variant LOW 660A>T Pro220Pro
M0010527 DMMCPGNC_00007 6224 4 Skin 0.21 protein_coding synonymous_variant LOW 612A>C Ala204Ala
M0010528 DMMCPGNC_00007 6254 4 Skin 0.21 protein_coding synonymous_variant LOW 582T>C Ser194Ser
M0010529 DMMCPGNC_00007 6359 4 Skin 0.21 protein_coding synonymous_variant LOW 477A>G Lys159Lys
M0010530 DMMCPGNC_00007 6371 4 Skin 0.21 protein_coding synonymous_variant LOW 465G>T Ala155Ala
M0010531 DMMCPGNC_00007 6374 4 Skin 0.21 protein_coding synonymous_variant LOW 462A>G Leu154Leu
M0010532 DMMCPGNC_00002 1336 3 Skin 0.16 protein_coding synonymous_variant LOW 504G>A Lys168Lys
M0010533 DMMCPGNC_00002 1339 3 Skin 0.16 protein_coding synonymous_variant LOW 507T>G Leu169Leu
M0010534 DMMCPGNC_00002 1366 3 Skin 0.16 protein_coding synonymous_variant LOW 534A>G Leu178Leu
M0010535 DMMCPGNC_00002 1388 3 Skin 0.16 protein_coding missense_variant MODERATE 556A>G Thr186Ala
M0010536 DMMCPGNC_00002 1414 3 Skin 0.16 protein_coding synonymous_variant LOW 582C>T His194His
M0010537 DMMCPGNC_00001 1575 4 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -923A>T None
M0010538 DMMCPGNC_00003 1716 3 Skin 0.16 protein_coding synonymous_variant LOW 79C>T Leu27Leu
M0010539 DMMCPGNC_00003 1757 3 Skin 0.16 protein_coding synonymous_variant LOW 120C>T Cys40Cys
M0010540 DMMCPGNC_00001 5404 3 Skin 0.16 protein_coding upstream_gene_variant MODIFIER -4752C>G None
M0010541 DMMCPGNC_00001 5457 3 Skin 0.16 protein_coding upstream_gene_variant MODIFIER -4805G>A None
M0010542 DMMCPGNC_00001 5463 3 Skin 0.16 protein_coding upstream_gene_variant MODIFIER -4811C>A None
M0010543 DMMCPGNC_00001 5470 3 Skin 0.16 protein_coding upstream_gene_variant MODIFIER -4818C>T None
M0010544 DMMCPGNC_00001 5501 3 Skin 0.16 protein_coding upstream_gene_variant MODIFIER -4849G>A None
M0010545 DMMCPGNC_00001 5526 3 Skin 0.16 protein_coding upstream_gene_variant MODIFIER -4874C>A None
M0010546 DMMCPGNC_00001 1570 3 Skin 0.16 protein_coding upstream_gene_variant MODIFIER -918T>A None
M0010547 DMMCPGNC_00010 8420 3 Skin 0.16 protein_coding synonymous_variant LOW 165C>T Thr55Thr
M0010548 DMMCPGNC_00002 80 3 Skin 0.16 protein_coding upstream_gene_variant MODIFIER -753A>G None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term