Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1678
  Reference Plasmid   1111525849486442_bin.45__k141_432129
  Reference Plasmid Size   6909
  Reference Plasmid GC Content   0.43
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0010749 CLMHKJGI_00002 642 3 Skin 0.50 protein_coding synonymous_variant LOW 2388C>T Ala796Ala
M0010750 CLMHKJGI_00002 786 3 Skin 0.50 protein_coding synonymous_variant LOW 2244A>G Lys748Lys
M0010751 CLMHKJGI_00002 972 3 Skin 0.50 protein_coding synonymous_variant LOW 2058A>C Thr686Thr
M0010752 CLMHKJGI_00002 1014 3 Skin 0.50 protein_coding synonymous_variant LOW 2016A>G Lys672Lys
M0010753 CLMHKJGI_00002 1017 3 Skin 0.50 protein_coding synonymous_variant LOW 2013C>T Cys671Cys
M0010754 CLMHKJGI_00002 1020 3 Skin 0.50 protein_coding synonymous_variant LOW 2010A>G Pro670Pro
M0010755 CLMHKJGI_00002 1098 3 Skin 0.50 protein_coding synonymous_variant LOW 1932T>G Thr644Thr
M0010756 CLMHKJGI_00002 1443 3 Skin 0.50 protein_coding synonymous_variant LOW 1587A>C Gly529Gly
M0010757 CLMHKJGI_00002 1587 3 Skin 0.50 protein_coding synonymous_variant LOW 1443C>T Ala481Ala
M0010758 CLMHKJGI_00002 1743 3 Skin 0.50 protein_coding synonymous_variant LOW 1287A>G Thr429Thr
M0010759 CLMHKJGI_00002 1923 3 Skin 0.50 protein_coding synonymous_variant LOW 1107G>A Val369Val
M0010760 CLMHKJGI_00002 1950 3 Skin 0.50 protein_coding synonymous_variant LOW 1080T>C Asn360Asn
M0010761 CLMHKJGI_00002 2193 3 Skin 0.50 protein_coding synonymous_variant LOW 837A>C Thr279Thr
M0010762 CLMHKJGI_00002 2547 3 Skin 0.50 protein_coding synonymous_variant LOW 483T>G Val161Val
M0010763 CLMHKJGI_00002 2565 3 Skin 0.50 protein_coding synonymous_variant LOW 465C>T Ala155Ala
M0010764 CLMHKJGI_00002 2592 3 Skin 0.50 protein_coding synonymous_variant LOW 438C>T Val146Val
M0010765 CLMHKJGI_00002 2595 3 Skin 0.50 protein_coding synonymous_variant LOW 435T>G Gly145Gly
M0010766 CLMHKJGI_00002 2963 4 Skin 0.67 protein_coding synonymous_variant LOW 67T>C Leu23Leu
M0010767 CLMHKJGI_00003 3460 4 Skin 0.67 protein_coding synonymous_variant LOW 849C>G Thr283Thr
M0010768 CLMHKJGI_00003 3516 4 Skin 0.67 protein_coding missense_variant MODERATE 793G>C Val265Leu
M0010769 CLMHKJGI_00003 3548 3 Skin 0.50 protein_coding missense_variant MODERATE 761G>T Trp254Leu
M0010770 CLMHKJGI_00003 3553 3 Skin 0.50 protein_coding synonymous_variant LOW 756G>T Pro252Pro
M0010771 CLMHKJGI_00003 3556 3 Skin 0.50 protein_coding synonymous_variant LOW 753T>A Ser251Ser
M0010772 CLMHKJGI_00003 3577 4 Skin 0.67 protein_coding synonymous_variant LOW 732C>T Ile244Ile
M0010773 CLMHKJGI_00003 3598 4 Skin 0.67 protein_coding synonymous_variant LOW 711T>C Asp237Asp
M0010774 CLMHKJGI_00003 3678 3 Skin 0.50 protein_coding missense_variant MODERATE 631A>G Asn211Asp
M0010775 CLMHKJGI_00003 4126 3 Skin 0.50 protein_coding synonymous_variant LOW 183C>T Gly61Gly
M0010776 CLMHKJGI_00003 4191 3 Skin 0.50 protein_coding missense_variant MODERATE 118A>G Asn40Asp
M0010777 CLMHKJGI_00003 3136 3 Skin 0.50 protein_coding synonymous_variant LOW 1173C>T Arg391Arg
M0010778 CLMHKJGI_00003 3379 3 Skin 0.50 protein_coding synonymous_variant LOW 930T>A Gly310Gly
M0010779 CLMHKJGI_00003 3382 3 Skin 0.50 protein_coding synonymous_variant LOW 927C>T Ser309Ser






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term