Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1684
  Reference Plasmid   1111525849486576_bin.18__k141_326945
  Reference Plasmid Size   452347
  Reference Plasmid GC Content   0.66
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0010861 ELNICGCM_00258 265878 4 Skin 0.11 protein_coding synonymous_variant LOW 1389T>C Val463Val
M0010862 ELNICGCM_00259 267422 4 Skin 0.11 protein_coding missense_variant MODERATE 493A>C Thr165Pro
M0010863 ELNICGCM_00262 269648 4 Skin 0.11 protein_coding synonymous_variant LOW 99A>C Ile33Ile
M0010864 ELNICGCM_00262 270012 4 Skin 0.11 protein_coding missense_variant MODERATE 463A>C Ser155Arg
M0010865 ELNICGCM_00266 274622 3 Skin 0.09 protein_coding synonymous_variant LOW 183A>G Leu61Leu
M0010866 ELNICGCM_00282 288755 3 Skin 0.09 protein_coding synonymous_variant LOW 303A>C Thr101Thr
M0010867 ELNICGCM_00286 291781 3 Skin 0.09 protein_coding synonymous_variant LOW 606A>G Ala202Ala
M0010868 ELNICGCM_00290 296291 3 Skin 0.09 protein_coding missense_variant MODERATE 721A>C Ser241Arg
M0010869 ELNICGCM_00351 361014 3 Skin 0.09 protein_coding missense_variant MODERATE 760A>G Thr254Ala
M0010870 ELNICGCM_00243 244254 6 Skin 0.17 protein_coding synonymous_variant LOW 474T>A Ala158Ala
M0010871 ELNICGCM_00243 244268 6 Skin 0.17 protein_coding missense_variant MODERATE 460T>A Leu154Met
M0010872 ELNICGCM_00244 247151 3 Skin 0.09 protein_coding synonymous_variant LOW 2301G>C Gly767Gly
M0010873 ELNICGCM_00155 162444 4 Skin 0.11 protein_coding synonymous_variant LOW 366T>C Thr122Thr
M0010874 ELNICGCM_00039 49372 5 Skin 0.14 protein_coding stop_lost&splice_region_variant HIGH 1015T>C Ter339Glnext*?
M0010875 ELNICGCM_00042 50316 4 Skin 0.11 protein_coding missense_variant MODERATE 49C>A Leu17Met






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
ELNICGCM_00128 QMW22845.1|GT4 74.6 1.09e-169 7 352 0.9058 0.9856





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term