Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1688
  Reference Plasmid   1111525849486576_bin.33__k141_98080
  Reference Plasmid Size   4550
  Reference Plasmid GC Content   0.70
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0010949 DDJJICFH_00001 141 5 Skin 0.71 protein_coding missense_variant MODERATE 434G>A Gly145Asp
M0010950 DDJJICFH_00001 320 3 Skin 0.43 protein_coding synonymous_variant LOW 255G>T Arg85Arg
M0010951 DDJJICFH_00001 327 4 Skin 0.57 protein_coding missense_variant MODERATE 248G>C Gly83Ala
M0010952 DDJJICFH_00001 328 3 Skin 0.43 protein_coding missense_variant MODERATE 247G>T Gly83Cys
M0010953 DDJJICFH_00001 331 4 Skin 0.57 protein_coding missense_variant MODERATE 244T>C Ser82Pro
M0010954 DDJJICFH_00001 362 4 Skin 0.57 protein_coding synonymous_variant LOW 213C>G Gly71Gly
M0010955 DDJJICFH_00001 389 3 Skin 0.43 protein_coding synonymous_variant LOW 186C>G Arg62Arg
M0010956 DDJJICFH_00001 422 3 Skin 0.43 protein_coding synonymous_variant LOW 153C>A Gly51Gly
M0010957 DDJJICFH_00001 455 3 Skin 0.43 protein_coding synonymous_variant LOW 120A>G Gly40Gly
M0010958 DDJJICFH_00001 652 4 Skin 0.57 protein_coding upstream_gene_variant MODIFIER -78C>G None
M0010959 DDJJICFH_00002 708 4 Skin 0.57 protein_coding missense_variant MODERATE 55C>G Leu19Val
M0010960 DDJJICFH_00002 710 4 Skin 0.57 protein_coding synonymous_variant LOW 57T>C Leu19Leu
M0010961 DDJJICFH_00002 720 4 Skin 0.57 protein_coding missense_variant MODERATE 67G>A Ala23Thr
M0010962 DDJJICFH_00002 725 3 Skin 0.43 protein_coding synonymous_variant LOW 72G>C Pro24Pro
M0010963 DDJJICFH_00002 791 5 Skin 0.71 protein_coding synonymous_variant LOW 138G>C Thr46Thr
M0010964 DDJJICFH_00002 795 5 Skin 0.71 protein_coding synonymous_variant LOW 142C>T Leu48Leu
M0010965 DDJJICFH_00002 1217 5 Skin 0.71 protein_coding synonymous_variant LOW 564C>G Arg188Arg
M0010966 DDJJICFH_00002 1422 4 Skin 0.57 protein_coding synonymous_variant LOW 769T>C Leu257Leu
M0010967 DDJJICFH_00003 1674 3 Skin 0.43 protein_coding synonymous_variant LOW 72G>C Gly24Gly
M0010968 DDJJICFH_00003 2007 3 Skin 0.43 protein_coding synonymous_variant LOW 405A>G Lys135Lys
M0010969 DDJJICFH_00002 950 3 Skin 0.43 protein_coding synonymous_variant LOW 297T>C Asp99Asp
M0010970 DDJJICFH_00002 977 3 Skin 0.43 protein_coding synonymous_variant LOW 324A>C Thr108Thr
M0010971 DDJJICFH_00002 1487 3 Skin 0.43 protein_coding synonymous_variant LOW 834C>T Ala278Ala
M0010972 DDJJICFH_00004 2464 3 Skin 0.43 protein_coding missense_variant MODERATE 11C>G Ala4Gly
M0010973 DDJJICFH_00004 2469 3 Skin 0.43 protein_coding missense_variant MODERATE 16G>A Asp6Asn
M0010974 DDJJICFH_00004 2489 3 Skin 0.43 protein_coding synonymous_variant LOW 36T>G Val12Val
M0010975 DDJJICFH_00004 2504 3 Skin 0.43 protein_coding synonymous_variant LOW 51C>G Val17Val
M0010976 DDJJICFH_00004 2555 3 Skin 0.43 protein_coding synonymous_variant LOW 102G>A Gln34Gln
M0010977 DDJJICFH_00004 2580 3 Skin 0.43 protein_coding missense_variant MODERATE 127C>G Gln43Glu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term