Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1691
  Reference Plasmid   1111525849486576_bin.91__k141_243806
  Reference Plasmid Size   7206
  Reference Plasmid GC Content   0.72
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0011092 PNHJIJHB_00003 1894 4 Skin 0.40 protein_coding missense_variant MODERATE 344A>C Asn115Thr
M0011093 PNHJIJHB_00003 1964 4 Skin 0.40 protein_coding synonymous_variant LOW 414A>T Ser138Ser
M0011094 PNHJIJHB_00003 2252 4 Skin 0.40 protein_coding missense_variant MODERATE 702C>G Ile234Met
M0011095 PNHJIJHB_00005 3285 3 Skin 0.30 protein_coding missense_variant MODERATE 67G>C Val23Leu
M0011096 PNHJIJHB_00005 3377 4 Skin 0.40 protein_coding synonymous_variant LOW 159A>G Leu53Leu
M0011097 PNHJIJHB_00005 3558 3 Skin 0.30 protein_coding missense_variant MODERATE 340A>G Ile114Val
M0011098 PNHJIJHB_00005 3890 3 Skin 0.30 protein_coding synonymous_variant LOW 672A>C Ala224Ala
M0011099 PNHJIJHB_00005 3896 3 Skin 0.30 protein_coding missense_variant MODERATE 678C>G Asp226Glu
M0011100 PNHJIJHB_00007 4536 5 Skin 0.50 protein_coding missense_variant MODERATE 86T>C Ile29Thr
M0011101 PNHJIJHB_00007 4610 5 Skin 0.50 protein_coding missense_variant MODERATE 160T>A Cys54Ser
M0011102 PNHJIJHB_00007 4613 5 Skin 0.50 protein_coding missense_variant MODERATE 163T>C Tyr55His
M0011103 PNHJIJHB_00007 5135 4 Skin 0.40 protein_coding missense_variant MODERATE 685A>G Thr229Ala
M0011104 PNHJIJHB_00007 5140 4 Skin 0.40 protein_coding synonymous_variant LOW 690A>G Glu230Glu
M0011105 PNHJIJHB_00007 5149 4 Skin 0.40 protein_coding synonymous_variant LOW 699G>A Lys233Lys
M0011106 PNHJIJHB_00007 5174 4 Skin 0.40 protein_coding missense_variant MODERATE 724C>G Arg242Gly
M0011107 PNHJIJHB_00007 5308 5 Skin 0.50 protein_coding synonymous_variant LOW 858C>T Tyr286Tyr
M0011108 PNHJIJHB_00005 3930 4 Skin 0.40 protein_coding missense_variant MODERATE 712C>G Arg238Gly
M0011109 PNHJIJHB_00008 5490 6 Skin 0.60 protein_coding synonymous_variant LOW 129G>C Ala43Ala
M0011110 PNHJIJHB_00008 5515 6 Skin 0.60 protein_coding missense_variant MODERATE 154T>A Leu52Met
M0011111 PNHJIJHB_00008 5557 7 Skin 0.70 protein_coding missense_variant MODERATE 196A>G Met66Val
M0011112 PNHJIJHB_00008 5829 7 Skin 0.70 protein_coding missense_variant MODERATE 468C>A Asp156Glu
M0011113 PNHJIJHB_00008 5955 7 Skin 0.70 protein_coding synonymous_variant LOW 594T>C Thr198Thr
M0011114 PNHJIJHB_00008 6291 6 Skin 0.60 protein_coding synonymous_variant LOW 930G>A Gln310Gln
M0011115 PNHJIJHB_00008 6292 6 Skin 0.60 protein_coding missense_variant MODERATE 931A>C Asn311His
M0011116 PNHJIJHB_00002 6440 6 Skin 0.60 protein_coding downstream_gene_variant MODIFIER *4886C>G None
M0011117 PNHJIJHB_00009 6926 3 Skin 0.30 protein_coding stop_gained HIGH 102C>G Tyr34*
M0011118 PNHJIJHB_00009 6929 5 Skin 0.50 protein_coding synonymous_variant LOW 99G>A Ala33Ala
M0011119 PNHJIJHB_00009 7082 4 Skin 0.40 protein_coding upstream_gene_variant MODIFIER -55C>T None
M0011120 PNHJIJHB_00009 7085 5 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -58T>C None
M0011121 PNHJIJHB_00001 358 3 Skin 0.30 protein_coding synonymous_variant LOW 348T>G Pro116Pro
M0011122 PNHJIJHB_00002 1293 4 Skin 0.40 protein_coding synonymous_variant LOW 594A>G Ala198Ala
M0011123 PNHJIJHB_00002 1299 4 Skin 0.40 protein_coding synonymous_variant LOW 600C>G Leu200Leu
M0011124 PNHJIJHB_00002 1338 3 Skin 0.30 protein_coding synonymous_variant LOW 639G>T Pro213Pro
M0011125 PNHJIJHB_00002 1476 4 Skin 0.40 protein_coding synonymous_variant LOW 777C>G Ala259Ala
M0011126 PNHJIJHB_00002 1479 4 Skin 0.40 protein_coding synonymous_variant LOW 780G>A Gly260Gly
M0011127 PNHJIJHB_00003 1716 4 Skin 0.40 protein_coding missense_variant MODERATE 166G>C Val56Leu
M0011128 PNHJIJHB_00003 1772 4 Skin 0.40 protein_coding synonymous_variant LOW 222T>C Ala74Ala
M0011129 PNHJIJHB_00003 1781 4 Skin 0.40 protein_coding synonymous_variant LOW 231T>G Ala77Ala
M0011130 PNHJIJHB_00003 1799 4 Skin 0.40 protein_coding synonymous_variant LOW 249A>C Arg83Arg
M0011131 PNHJIJHB_00003 2495 7 Skin 0.70 protein_coding synonymous_variant LOW 945C>T Asp315Asp
M0011132 PNHJIJHB_00007 4528 4 Skin 0.40 protein_coding synonymous_variant LOW 78C>T Pro26Pro
M0011133 PNHJIJHB_00007 4721 3 Skin 0.30 protein_coding missense_variant MODERATE 271G>A Gly91Ser
M0011134 PNHJIJHB_00008 5711 3 Skin 0.30 protein_coding missense_variant MODERATE 350T>C Ile117Thr
M0011135 PNHJIJHB_00008 5739 3 Skin 0.30 protein_coding synonymous_variant LOW 378A>G Ala126Ala
M0011136 PNHJIJHB_00008 5824 3 Skin 0.30 protein_coding missense_variant MODERATE 463A>G Ser155Gly
M0011137 PNHJIJHB_00008 5825 3 Skin 0.30 protein_coding missense_variant MODERATE 464G>C Ser155Thr
M0011138 PNHJIJHB_00008 5865 3 Skin 0.30 protein_coding synonymous_variant LOW 504G>C Ala168Ala
M0011139 PNHJIJHB_00008 5871 3 Skin 0.30 protein_coding synonymous_variant LOW 510T>C Arg170Arg
M0011140 PNHJIJHB_00008 5886 3 Skin 0.30 protein_coding synonymous_variant LOW 525A>G Gly175Gly
M0011141 PNHJIJHB_00008 5889 3 Skin 0.30 protein_coding synonymous_variant LOW 528G>A Arg176Arg
M0011142 PNHJIJHB_00008 5946 3 Skin 0.30 protein_coding synonymous_variant LOW 585C>T Gly195Gly
M0011143 PNHJIJHB_00008 5957 3 Skin 0.30 protein_coding missense_variant MODERATE 596G>A Gly199Asp
M0011144 PNHJIJHB_00008 5958 3 Skin 0.30 protein_coding synonymous_variant LOW 597C>G Gly199Gly
M0011145 PNHJIJHB_00008 6064 3 Skin 0.30 protein_coding missense_variant MODERATE 703T>G Ser235Ala
M0011146 PNHJIJHB_00008 6177 3 Skin 0.30 protein_coding synonymous_variant LOW 816C>G Ala272Ala
M0011147 PNHJIJHB_00008 6195 3 Skin 0.30 protein_coding synonymous_variant LOW 834A>G Ala278Ala
M0011148 PNHJIJHB_00002 1176 3 Skin 0.30 protein_coding synonymous_variant LOW 477C>G Arg159Arg
M0011149 PNHJIJHB_00002 1410 3 Skin 0.30 protein_coding synonymous_variant LOW 711C>A Gly237Gly
M0011150 PNHJIJHB_00002 1419 3 Skin 0.30 protein_coding synonymous_variant LOW 720T>C Leu240Leu
M0011151 PNHJIJHB_00008 5538 3 Skin 0.30 protein_coding synonymous_variant LOW 177C>G Val59Val
M0011152 PNHJIJHB_00005 3551 3 Skin 0.30 protein_coding synonymous_variant LOW 333A>G Leu111Leu
M0011153 PNHJIJHB_00007 5284 3 Skin 0.30 protein_coding synonymous_variant LOW 834A>G Ala278Ala
M0011154 PNHJIJHB_00007 5328 3 Skin 0.30 protein_coding missense_variant MODERATE 878C>T Ala293Val
M0011155 PNHJIJHB_00007 5343 3 Skin 0.30 protein_coding missense_variant MODERATE 893A>G Asn298Ser
M0011156 PNHJIJHB_00007 5344 3 Skin 0.30 protein_coding missense_variant MODERATE 894C>G Asn298Lys






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term