Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1693
  Reference Plasmid   1111525849486576_bin.91__k141_673263
  Reference Plasmid Size   2966
  Reference Plasmid GC Content   0.69
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0011180 MPEKBHNG_00002 992 3 Skin 0.75 protein_coding synonymous_variant LOW 1002A>G Pro334Pro
M0011181 MPEKBHNG_00002 1057 3 Skin 0.75 protein_coding missense_variant MODERATE 937T>C Ser313Pro
M0011182 MPEKBHNG_00002 1352 3 Skin 0.75 protein_coding synonymous_variant LOW 642T>G Leu214Leu
M0011183 MPEKBHNG_00002 1371 3 Skin 0.75 protein_coding missense_variant MODERATE 623T>C Leu208Pro
M0011184 MPEKBHNG_00002 1372 3 Skin 0.75 protein_coding missense_variant MODERATE 622C>G Leu208Val
M0011185 MPEKBHNG_00002 1885 3 Skin 0.75 protein_coding missense_variant MODERATE 109T>G Cys37Gly
M0011186 MPEKBHNG_00002 1918 3 Skin 0.75 protein_coding missense_variant MODERATE 76A>C Lys26Gln
M0011187 MPEKBHNG_00002 2045 3 Skin 0.75 protein_coding upstream_gene_variant MODIFIER -52T>C None
M0011188 MPEKBHNG_00003 2177 3 Skin 0.75 protein_coding synonymous_variant LOW 702T>C Ile234Ile
M0011189 MPEKBHNG_00003 2196 3 Skin 0.75 protein_coding missense_variant MODERATE 683G>T Ser228Ile
M0011190 MPEKBHNG_00003 2204 3 Skin 0.75 protein_coding synonymous_variant LOW 675T>G Leu225Leu
M0011191 MPEKBHNG_00003 2207 3 Skin 0.75 protein_coding synonymous_variant LOW 672C>G Gly224Gly
M0011192 MPEKBHNG_00003 2301 3 Skin 0.75 protein_coding missense_variant MODERATE 578A>C Glu193Ala
M0011193 MPEKBHNG_00003 2327 3 Skin 0.75 protein_coding synonymous_variant LOW 552T>C Ala184Ala
M0011194 MPEKBHNG_00003 2678 3 Skin 0.75 protein_coding synonymous_variant LOW 201A>G Thr67Thr
M0011195 MPEKBHNG_00003 2708 3 Skin 0.75 protein_coding synonymous_variant LOW 171G>C Ala57Ala
M0011196 MPEKBHNG_00003 2714 3 Skin 0.75 protein_coding synonymous_variant LOW 165T>C Tyr55Tyr






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term