Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1694
  Reference Plasmid   1111525849486576_bin.91__k141_749267
  Reference Plasmid Size   3050
  Reference Plasmid GC Content   0.70
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0011197 LHPAEGOE_00001 354 5 Skin 0.71 protein_coding synonymous_variant LOW 348A>C Gly116Gly
M0011198 LHPAEGOE_00001 357 5 Skin 0.71 protein_coding synonymous_variant LOW 351A>C Arg117Arg
M0011199 LHPAEGOE_00001 384 3 Skin 0.43 protein_coding synonymous_variant LOW 378T>C Phe126Phe
M0011200 LHPAEGOE_00001 462 6 Skin 0.86 protein_coding synonymous_variant LOW 456A>C Val152Val
M0011201 LHPAEGOE_00002 634 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -14A>G None
M0011202 LHPAEGOE_00002 950 4 Skin 0.57 protein_coding synonymous_variant LOW 303T>G Ala101Ala
M0011203 LHPAEGOE_00002 1528 3 Skin 0.43 protein_coding missense_variant MODERATE 881A>G Asn294Ser
M0011204 LHPAEGOE_00002 1529 3 Skin 0.43 protein_coding missense_variant MODERATE 882T>G Asn294Lys
M0011205 LHPAEGOE_00002 1604 3 Skin 0.43 protein_coding synonymous_variant LOW 957T>C Ile319Ile
M0011206 LHPAEGOE_00002 1655 3 Skin 0.43 protein_coding synonymous_variant LOW 1008C>T Gly336Gly
M0011207 LHPAEGOE_00002 1787 7 Skin 1.00 protein_coding synonymous_variant LOW 1140A>G Arg380Arg
M0011208 LHPAEGOE_00001 2328 7 Skin 1.00 protein_coding downstream_gene_variant MODIFIER *1782C>G None
M0011209 LHPAEGOE_00003 2436 3 Skin 0.43 protein_coding synonymous_variant LOW 186A>G Pro62Pro
M0011210 LHPAEGOE_00003 2608 3 Skin 0.43 protein_coding missense_variant MODERATE 14T>C Val5Ala
M0011211 LHPAEGOE_00003 2628 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -7G>A None
M0011212 LHPAEGOE_00003 2679 4 Skin 0.57 protein_coding upstream_gene_variant MODIFIER -58T>G None
M0011213 LHPAEGOE_00003 2761 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -140C>T None
M0011214 LHPAEGOE_00003 2892 7 Skin 1.00 protein_coding upstream_gene_variant MODIFIER -271A>G None
M0011215 LHPAEGOE_00003 2991 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -370C>A None
M0011216 LHPAEGOE_00001 2346 5 Skin 0.71 protein_coding downstream_gene_variant MODIFIER *1800C>T None
M0011217 LHPAEGOE_00003 2931 4 Skin 0.57 protein_coding upstream_gene_variant MODIFIER -310C>T None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
LHPAEGOE_00002 QJD17247.1|CE4 88.9 0 1 476 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term