Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1706
  Reference Plasmid   1111525849633275_bin.1__k141_22350
  Reference Plasmid Size   54398
  Reference Plasmid GC Content   0.58
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0011815 FJLJNDKN_00031 33628 3 Skin 0.06 protein_coding synonymous_variant LOW 468G>A Gln156Gln
M0011816 FJLJNDKN_00020 26663 15 Skin 0.28 protein_coding upstream_gene_variant MODIFIER -4851T>G None
M0011817 FJLJNDKN_00027 29228 23 Skin 0.43 protein_coding missense_variant MODERATE 799T>C Phe267Leu
M0011818 FJLJNDKN_00030 32965 4 Skin 0.08 protein_coding synonymous_variant LOW 72C>G Val24Val
M0011819 FJLJNDKN_00033 36211 25 Skin 0.47 protein_coding synonymous_variant LOW 774G>T Gly258Gly
M0011820 FJLJNDKN_00031 33166 3 Skin 0.06 protein_coding synonymous_variant LOW 6C>G Gly2Gly
M0011821 FJLJNDKN_00032 34847 3 Skin 0.06 protein_coding synonymous_variant LOW 663T>C Leu221Leu
M0011822 FJLJNDKN_00029 31228 3 Skin 0.06 protein_coding synonymous_variant LOW 393C>T Leu131Leu
M0011823 FJLJNDKN_00030 31861 3 Skin 0.06 protein_coding synonymous_variant LOW 1176A>G Leu392Leu
M0011824 FJLJNDKN_00031 33469 3 Skin 0.06 protein_coding synonymous_variant LOW 309A>G Val103Val
M0011825 FJLJNDKN_00031 34000 6 Skin 0.11 protein_coding synonymous_variant LOW 840A>G Val280Val
M0011826 FJLJNDKN_00031 33403 5 Skin 0.09 protein_coding synonymous_variant LOW 243T>C Thr81Thr
M0011827 FJLJNDKN_00028 30095 4 Skin 0.08 protein_coding missense_variant MODERATE 385A>G Ser129Gly
M0011828 FJLJNDKN_00028 30099 4 Skin 0.08 protein_coding synonymous_variant LOW 381G>A Glu127Glu
M0011829 FJLJNDKN_00028 30111 4 Skin 0.08 protein_coding synonymous_variant LOW 369C>T Asp123Asp
M0011830 FJLJNDKN_00039 42592 8 Skin 0.15 protein_coding synonymous_variant LOW 1717T>C Leu573Leu
M0011831 FJLJNDKN_00039 42761 7 Skin 0.13 protein_coding missense_variant MODERATE 1548A>C Glu516Asp
M0011832 FJLJNDKN_00034 36809 3 Skin 0.06 protein_coding synonymous_variant LOW 324G>A Pro108Pro
M0011833 FJLJNDKN_00026 31695 3 Skin 0.06 protein_coding upstream_gene_variant MODIFIER -3286G>A None
M0011834 FJLJNDKN_00014 12253 4 Skin 0.08 protein_coding synonymous_variant LOW 544A>C Arg182Arg
M0011835 FJLJNDKN_00020 21456 3 Skin 0.06 protein_coding synonymous_variant LOW 357G>A Glu119Glu
M0011836 FJLJNDKN_00033 35590 3 Skin 0.06 protein_coding synonymous_variant LOW 153C>T Leu51Leu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition
FJLJNDKN_00037 VFG015780 Acylhomoserine lactone synthase 95.7 4.4e-143 1 256 1.0 0.9808 Biofilm 1-acyl-sn-glycerol-3-phosphate acyltransferase prediction







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group
FJLJNDKN_00020 Zinc (Zn), Cadmium (Cd) 77.8 0 1 1043 0.9905 0.9924 experiment
FJLJNDKN_00020 Zinc (Zn), Cadmium (Cd) 78.2 0 1 1043 0.9905 0.9924 prediction






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant
FJLJNDKN_00042 PHI:5298 PA0011 74.2 8.3e-133 1 295 1.0000 1.0000 eudicots nosocomial infection 2-OH-lauroytransferase reduced virulence






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
FJLJNDKN_00011 AVD80780.1|GT83 100 0 1 484 1 1
FJLJNDKN_00012 ATN09722.1|GT2 100 4.05e-238 1 327 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
FJLJNDKN_00015 1.B.5.1.1 72.7 2.9e-190 5 435 0.9908 0.9750 1 Channels/Pores 1.B β-Barrel Porins 1.B.5 The Pseudomonas OprP Porin (POP) Family
FJLJNDKN_00018 3.A.3.6.11 100 0 1 665 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.3 The P-type ATPase (P-ATPase) Superfamily
FJLJNDKN_00020 2.A.6.1.5 100 0 1 1053 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.6 The Resistance-Nodulation-Cell Division (RND) Superfamily