Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1708
  Reference Plasmid   1111525849633549_bin.9__k141_413041
  Reference Plasmid Size   11808
  Reference Plasmid GC Content   0.52
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0011837 JNCOPABN_00002 2010 3 Skin 0.50 protein_coding missense_variant MODERATE 122C>T Ala41Val
M0011838 JNCOPABN_00002 3654 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -1523C>G None
M0011839 JNCOPABN_00002 3669 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -1538C>T None
M0011840 JNCOPABN_00002 3696 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -1565C>G None
M0011841 JNCOPABN_00004 3713 3 Skin 0.50 protein_coding missense_variant MODERATE 11A>G Asn4Ser
M0011842 JNCOPABN_00004 3717 3 Skin 0.50 protein_coding synonymous_variant LOW 15G>A Ala5Ala
M0011843 JNCOPABN_00004 3724 3 Skin 0.50 protein_coding missense_variant MODERATE 22A>G Thr8Ala
M0011844 JNCOPABN_00004 3729 3 Skin 0.50 protein_coding synonymous_variant LOW 27C>T His9His
M0011845 JNCOPABN_00004 3804 3 Skin 0.50 protein_coding synonymous_variant LOW 102G>A Val34Val
M0011846 JNCOPABN_00004 3809 3 Skin 0.50 protein_coding missense_variant MODERATE 107T>C Val36Ala
M0011847 JNCOPABN_00004 3822 3 Skin 0.50 protein_coding synonymous_variant LOW 120T>C Val40Val
M0011848 JNCOPABN_00002 4463 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -2332A>T None
M0011849 JNCOPABN_00002 4529 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -2398G>A None
M0011850 JNCOPABN_00002 4648 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -2517A>G None
M0011851 JNCOPABN_00006 6935 3 Skin 0.50 protein_coding missense_variant MODERATE 1288A>G Lys430Glu
M0011852 JNCOPABN_00007 7525 3 Skin 0.50 protein_coding synonymous_variant LOW 384G>C Ala128Ala
M0011853 JNCOPABN_00007 7717 3 Skin 0.50 protein_coding missense_variant MODERATE 576G>A Met192Ile
M0011854 JNCOPABN_00007 7805 3 Skin 0.50 protein_coding synonymous_variant LOW 664T>C Leu222Leu
M0011855 JNCOPABN_00007 7843 3 Skin 0.50 protein_coding missense_variant MODERATE 702T>G Ser234Arg
M0011856 JNCOPABN_00007 7854 3 Skin 0.50 protein_coding missense_variant MODERATE 713G>T Gly238Val
M0011857 JNCOPABN_00007 7865 3 Skin 0.50 protein_coding missense_variant MODERATE 724C>T Pro242Ser
M0011858 JNCOPABN_00008 7940 3 Skin 0.50 protein_coding missense_variant MODERATE 1298G>A Arg433Gln
M0011859 JNCOPABN_00008 8676 3 Skin 0.50 protein_coding synonymous_variant LOW 562T>C Leu188Leu
M0011860 JNCOPABN_00008 8734 3 Skin 0.50 protein_coding synonymous_variant LOW 504G>A Pro168Pro
M0011861 JNCOPABN_00008 8755 3 Skin 0.50 protein_coding synonymous_variant LOW 483G>A Val161Val
M0011862 JNCOPABN_00008 8854 3 Skin 0.50 protein_coding synonymous_variant LOW 384A>G Lys128Lys
M0011863 JNCOPABN_00008 8860 3 Skin 0.50 protein_coding synonymous_variant LOW 378T>G Arg126Arg
M0011864 JNCOPABN_00008 8878 3 Skin 0.50 protein_coding synonymous_variant LOW 360T>C His120His
M0011865 JNCOPABN_00008 8896 3 Skin 0.50 protein_coding synonymous_variant LOW 342A>G Ala114Ala
M0011866 JNCOPABN_00008 8908 3 Skin 0.50 protein_coding synonymous_variant LOW 330A>G Pro110Pro
M0011867 JNCOPABN_00008 8938 3 Skin 0.50 protein_coding synonymous_variant LOW 300C>A Ala100Ala
M0011868 JNCOPABN_00008 8953 3 Skin 0.50 protein_coding synonymous_variant LOW 285A>C Pro95Pro
M0011869 JNCOPABN_00008 9010 3 Skin 0.50 protein_coding synonymous_variant LOW 228G>A Lys76Lys
M0011870 JNCOPABN_00008 9058 3 Skin 0.50 protein_coding synonymous_variant LOW 180T>C Ala60Ala
M0011871 JNCOPABN_00009 9246 3 Skin 0.50 protein_coding missense_variant MODERATE 665T>C Ile222Thr
M0011872 JNCOPABN_00009 9470 3 Skin 0.50 protein_coding synonymous_variant LOW 441C>T Asn147Asn
M0011873 JNCOPABN_00009 9494 3 Skin 0.50 protein_coding synonymous_variant LOW 417T>C Ala139Ala
M0011874 JNCOPABN_00009 9572 3 Skin 0.50 protein_coding synonymous_variant LOW 339T>C Arg113Arg
M0011875 JNCOPABN_00009 9644 3 Skin 0.50 protein_coding synonymous_variant LOW 267T>C Gly89Gly
M0011876 JNCOPABN_00009 9671 3 Skin 0.50 protein_coding synonymous_variant LOW 240A>G Ala80Ala
M0011877 JNCOPABN_00009 9730 3 Skin 0.50 protein_coding missense_variant MODERATE 181T>A Leu61Met
M0011878 JNCOPABN_00009 9770 3 Skin 0.50 protein_coding synonymous_variant LOW 141C>T His47His
M0011879 JNCOPABN_00009 9815 3 Skin 0.50 protein_coding synonymous_variant LOW 96C>T Arg32Arg
M0011880 JNCOPABN_00009 9866 3 Skin 0.50 protein_coding synonymous_variant LOW 45A>G Glu15Glu
M0011881 JNCOPABN_00010 9993 3 Skin 0.50 protein_coding synonymous_variant LOW 1575C>T Thr525Thr
M0011882 JNCOPABN_00010 10036 3 Skin 0.50 protein_coding missense_variant MODERATE 1532G>A Arg511Gln
M0011883 JNCOPABN_00010 10083 3 Skin 0.50 protein_coding synonymous_variant LOW 1485G>A Ser495Ser
M0011884 JNCOPABN_00010 10410 3 Skin 0.50 protein_coding synonymous_variant LOW 1158G>A Leu386Leu
M0011885 JNCOPABN_00010 10458 3 Skin 0.50 protein_coding synonymous_variant LOW 1110A>G Leu370Leu
M0011886 JNCOPABN_00010 10479 3 Skin 0.50 protein_coding synonymous_variant LOW 1089G>T Leu363Leu
M0011887 JNCOPABN_00010 10485 3 Skin 0.50 protein_coding synonymous_variant LOW 1083C>G Leu361Leu
M0011888 JNCOPABN_00010 10533 3 Skin 0.50 protein_coding synonymous_variant LOW 1035G>A Glu345Glu
M0011889 JNCOPABN_00010 10539 3 Skin 0.50 protein_coding synonymous_variant LOW 1029G>A Val343Val
M0011890 JNCOPABN_00010 10548 3 Skin 0.50 protein_coding synonymous_variant LOW 1020G>A Gln340Gln
M0011891 JNCOPABN_00010 10557 3 Skin 0.50 protein_coding synonymous_variant LOW 1011T>C Thr337Thr
M0011892 JNCOPABN_00010 10647 3 Skin 0.50 protein_coding synonymous_variant LOW 921C>T Arg307Arg
M0011893 JNCOPABN_00010 11109 3 Skin 0.50 protein_coding synonymous_variant LOW 459A>G Val153Val
M0011894 JNCOPABN_00008 11603 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -2366T>G None
M0011895 JNCOPABN_00008 11664 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -2427A>G None
M0011896 JNCOPABN_00008 11670 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -2433A>G None
M0011897 JNCOPABN_00008 11687 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -2450C>G None
M0011898 JNCOPABN_00008 11693 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -2456G>A None
M0011899 JNCOPABN_00008 11695 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -2458C>A None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term