Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1716
  Reference Plasmid   1111525849638712_bin.21__k141_225379
  Reference Plasmid Size   4617
  Reference Plasmid GC Content   0.44
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0012177 ECMGKEDD_00002 1505 3 Skin 1.00 protein_coding synonymous_variant LOW 486T>A Ser162Ser
M0012178 ECMGKEDD_00002 1613 3 Skin 1.00 protein_coding synonymous_variant LOW 594T>C Asn198Asn
M0012179 ECMGKEDD_00002 1655 3 Skin 1.00 protein_coding synonymous_variant LOW 636G>T Pro212Pro
M0012180 ECMGKEDD_00002 1694 3 Skin 1.00 protein_coding synonymous_variant LOW 675C>G Ala225Ala
M0012181 ECMGKEDD_00002 1745 3 Skin 1.00 protein_coding synonymous_variant LOW 726G>A Val242Val
M0012182 ECMGKEDD_00002 1781 3 Skin 1.00 protein_coding synonymous_variant LOW 762G>A Leu254Leu
M0012183 ECMGKEDD_00002 1843 3 Skin 1.00 protein_coding missense_variant MODERATE 824G>A Arg275Gln
M0012184 ECMGKEDD_00002 1862 3 Skin 1.00 protein_coding synonymous_variant LOW 843A>G Thr281Thr
M0012185 ECMGKEDD_00002 1892 3 Skin 1.00 protein_coding synonymous_variant LOW 873T>C Phe291Phe
M0012186 ECMGKEDD_00002 1904 3 Skin 1.00 protein_coding synonymous_variant LOW 885A>G Pro295Pro
M0012187 ECMGKEDD_00002 1926 3 Skin 1.00 protein_coding synonymous_variant LOW 907T>C Leu303Leu
M0012188 ECMGKEDD_00002 1931 3 Skin 1.00 protein_coding synonymous_variant LOW 912T>C Ala304Ala
M0012189 ECMGKEDD_00002 1961 3 Skin 1.00 protein_coding synonymous_variant LOW 942A>C Ala314Ala
M0012190 ECMGKEDD_00002 1964 3 Skin 1.00 protein_coding synonymous_variant LOW 945A>G Gln315Gln
M0012191 ECMGKEDD_00002 1967 3 Skin 1.00 protein_coding synonymous_variant LOW 948T>A Arg316Arg
M0012192 ECMGKEDD_00002 1970 3 Skin 1.00 protein_coding synonymous_variant LOW 951A>G Ala317Ala
M0012193 ECMGKEDD_00002 1973 3 Skin 1.00 protein_coding synonymous_variant LOW 954C>T Gly318Gly
M0012194 ECMGKEDD_00002 1979 3 Skin 1.00 protein_coding synonymous_variant LOW 960A>G Gln320Gln
M0012195 ECMGKEDD_00002 2017 3 Skin 1.00 protein_coding missense_variant MODERATE 998C>G Thr333Ser
M0012196 ECMGKEDD_00002 2041 3 Skin 1.00 protein_coding missense_variant MODERATE 1022A>C Lys341Thr
M0012197 ECMGKEDD_00002 2072 3 Skin 1.00 protein_coding synonymous_variant LOW 1053C>T Cys351Cys
M0012198 ECMGKEDD_00002 2073 3 Skin 1.00 protein_coding missense_variant MODERATE 1054A>C Lys352Gln
M0012199 ECMGKEDD_00002 2112 3 Skin 1.00 protein_coding missense_variant MODERATE 1093T>C Phe365Leu
M0012200 ECMGKEDD_00002 2204 3 Skin 1.00 protein_coding synonymous_variant LOW 1185T>C Tyr395Tyr
M0012201 ECMGKEDD_00002 2207 3 Skin 1.00 protein_coding synonymous_variant LOW 1188A>G Lys396Lys
M0012202 ECMGKEDD_00002 2216 3 Skin 1.00 protein_coding synonymous_variant LOW 1197T>C Pro399Pro
M0012203 ECMGKEDD_00002 2369 3 Skin 1.00 protein_coding synonymous_variant LOW 1350C>T Tyr450Tyr
M0012204 ECMGKEDD_00002 2399 3 Skin 1.00 protein_coding synonymous_variant LOW 1380C>T His460His
M0012205 ECMGKEDD_00002 2633 3 Skin 1.00 protein_coding synonymous_variant LOW 1614T>C Asn538Asn
M0012206 ECMGKEDD_00003 2679 3 Skin 1.00 protein_coding upstream_gene_variant MODIFIER -3G>A None
M0012207 ECMGKEDD_00003 2702 3 Skin 1.00 protein_coding synonymous_variant LOW 21A>C Ile7Ile
M0012208 ECMGKEDD_00003 2720 3 Skin 1.00 protein_coding synonymous_variant LOW 39C>T Ile13Ile






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term