Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1717
  Reference Plasmid   1111525849638712_bin.7_new__k141_170826
  Reference Plasmid Size   4351
  Reference Plasmid GC Content   0.41
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0012209 COCNKFOK_00004 2517 3 Skin 0.50 protein_coding synonymous_variant LOW 957T>G Val319Val
M0012210 COCNKFOK_00004 2586 4 Skin 0.67 protein_coding synonymous_variant LOW 888C>T Ile296Ile
M0012211 COCNKFOK_00004 2607 4 Skin 0.67 protein_coding missense_variant MODERATE 867A>C Glu289Asp
M0012212 COCNKFOK_00004 2620 4 Skin 0.67 protein_coding missense_variant MODERATE 854A>T Lys285Met
M0012213 COCNKFOK_00004 2634 4 Skin 0.67 protein_coding synonymous_variant LOW 840C>T Leu280Leu
M0012214 COCNKFOK_00004 2673 4 Skin 0.67 protein_coding synonymous_variant LOW 801T>C Ser267Ser
M0012215 COCNKFOK_00004 2681 4 Skin 0.67 protein_coding missense_variant MODERATE 793G>T Ala265Ser
M0012216 COCNKFOK_00004 2691 4 Skin 0.67 protein_coding synonymous_variant LOW 783A>G Gly261Gly
M0012217 COCNKFOK_00004 2777 3 Skin 0.50 protein_coding missense_variant MODERATE 697C>T Pro233Ser
M0012218 COCNKFOK_00004 2805 3 Skin 0.50 protein_coding synonymous_variant LOW 669T>C Ala223Ala
M0012219 COCNKFOK_00004 2808 3 Skin 0.50 protein_coding synonymous_variant LOW 666C>T Pro222Pro
M0012220 COCNKFOK_00004 2811 3 Skin 0.50 protein_coding synonymous_variant LOW 663G>T Thr221Thr
M0012221 COCNKFOK_00004 2812 3 Skin 0.50 protein_coding missense_variant MODERATE 662C>T Thr221Met
M0012222 COCNKFOK_00004 2813 3 Skin 0.50 protein_coding missense_variant MODERATE 661A>G Thr221Ala
M0012223 COCNKFOK_00004 2814 3 Skin 0.50 protein_coding synonymous_variant LOW 660G>C Ser220Ser
M0012224 COCNKFOK_00004 2844 3 Skin 0.50 protein_coding missense_variant MODERATE 630C>A His210Gln
M0012225 COCNKFOK_00004 2861 3 Skin 0.50 protein_coding missense_variant MODERATE 613G>A Ala205Thr
M0012226 COCNKFOK_00004 2877 3 Skin 0.50 protein_coding synonymous_variant LOW 597C>T His199His






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term