Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1718
  Reference Plasmid   1111525849638922_bin.1__k141_1247394
  Reference Plasmid Size   3327
  Reference Plasmid GC Content   0.44
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0012227 HOKBJALF_00001 169 3 Skin 0.60 protein_coding synonymous_variant LOW 126T>G Thr42Thr
M0012228 HOKBJALF_00002 464 5 Skin 1.00 protein_coding synonymous_variant LOW 483G>A Arg161Arg
M0012229 HOKBJALF_00002 539 4 Skin 0.80 protein_coding synonymous_variant LOW 408G>C Ala136Ala
M0012230 HOKBJALF_00002 770 3 Skin 0.60 protein_coding synonymous_variant LOW 177A>G Ala59Ala
M0012231 HOKBJALF_00002 785 3 Skin 0.60 protein_coding synonymous_variant LOW 162T>C His54His
M0012232 HOKBJALF_00002 803 4 Skin 0.80 protein_coding synonymous_variant LOW 144T>A Thr48Thr
M0012233 HOKBJALF_00002 848 3 Skin 0.60 protein_coding synonymous_variant LOW 99C>T His33His
M0012234 HOKBJALF_00002 866 3 Skin 0.60 protein_coding synonymous_variant LOW 81G>A Ala27Ala
M0012235 HOKBJALF_00002 1002 4 Skin 0.80 protein_coding upstream_gene_variant MODIFIER -56C>T None
M0012236 HOKBJALF_00002 1067 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -121T>C None
M0012237 HOKBJALF_00003 1139 4 Skin 0.80 protein_coding synonymous_variant LOW 798G>A Glu266Glu
M0012238 HOKBJALF_00003 1256 3 Skin 0.60 protein_coding synonymous_variant LOW 681T>C Gly227Gly
M0012239 HOKBJALF_00003 1405 5 Skin 1.00 protein_coding missense_variant MODERATE 532T>A Leu178Met
M0012240 HOKBJALF_00003 1412 5 Skin 1.00 protein_coding synonymous_variant LOW 525G>C Ala175Ala
M0012241 HOKBJALF_00003 1484 5 Skin 1.00 protein_coding synonymous_variant LOW 453T>C Ile151Ile
M0012242 HOKBJALF_00003 1490 5 Skin 1.00 protein_coding synonymous_variant LOW 447T>C Gly149Gly
M0012243 HOKBJALF_00003 1514 5 Skin 1.00 protein_coding synonymous_variant LOW 423A>G Ser141Ser
M0012244 HOKBJALF_00003 1538 4 Skin 0.80 protein_coding synonymous_variant LOW 399A>G Glu133Glu
M0012245 HOKBJALF_00002 470 4 Skin 0.80 protein_coding synonymous_variant LOW 477A>G Ala159Ala
M0012246 HOKBJALF_00002 574 4 Skin 0.80 protein_coding synonymous_variant LOW 373C>T Leu125Leu
M0012247 HOKBJALF_00002 575 4 Skin 0.80 protein_coding synonymous_variant LOW 372A>C Gly124Gly
M0012248 HOKBJALF_00002 640 3 Skin 0.60 protein_coding missense_variant MODERATE 307A>G Ile103Val
M0012249 HOKBJALF_00002 960 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -14G>A None
M0012250 HOKBJALF_00002 1122 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -176A>G None
M0012251 HOKBJALF_00003 1406 4 Skin 0.80 protein_coding synonymous_variant LOW 531A>T Ser177Ser
M0012252 HOKBJALF_00003 1664 3 Skin 0.60 protein_coding synonymous_variant LOW 273G>C Ala91Ala
M0012253 HOKBJALF_00003 1764 4 Skin 0.80 protein_coding missense_variant MODERATE 173G>A Arg58Lys
M0012254 HOKBJALF_00002 2059 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -1113A>G None
M0012255 HOKBJALF_00002 2060 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -1114T>C None
M0012256 HOKBJALF_00004 2201 4 Skin 0.80 protein_coding missense_variant MODERATE 112C>G Gln38Glu
M0012257 HOKBJALF_00004 2221 4 Skin 0.80 protein_coding synonymous_variant LOW 132G>A Leu44Leu
M0012258 HOKBJALF_00004 2239 3 Skin 0.60 protein_coding synonymous_variant LOW 150C>T Arg50Arg
M0012259 HOKBJALF_00002 404 3 Skin 0.60 protein_coding synonymous_variant LOW 543T>C Gly181Gly
M0012260 HOKBJALF_00002 407 3 Skin 0.60 protein_coding synonymous_variant LOW 540C>G Gly180Gly
M0012261 HOKBJALF_00004 2182 3 Skin 0.60 protein_coding synonymous_variant LOW 93C>T Leu31Leu
M0012262 HOKBJALF_00004 2203 3 Skin 0.60 protein_coding missense_variant MODERATE 114G>C Gln38His
M0012263 HOKBJALF_00004 2215 3 Skin 0.60 protein_coding synonymous_variant LOW 126G>A Glu42Glu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term