Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1721
  Reference Plasmid   1111525849639004_bin.1__k141_1195101
  Reference Plasmid Size   7840
  Reference Plasmid GC Content   0.37
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0012280 BKBILMHE_00003 5154 3 Skin 0.14 protein_coding synonymous_variant LOW 1803C>T Asp601Asp
M0012281 BKBILMHE_00003 5215 6 Skin 0.29 protein_coding missense_variant MODERATE 1864G>A Ala622Thr
M0012282 BKBILMHE_00004 6105 4 Skin 0.19 protein_coding synonymous_variant LOW 102A>G Gln34Gln
M0012283 BKBILMHE_00004 6191 4 Skin 0.19 protein_coding synonymous_variant LOW 16T>C Leu6Leu
M0012284 BKBILMHE_00005 6691 4 Skin 0.19 protein_coding synonymous_variant LOW 183A>G Leu61Leu
M0012285 BKBILMHE_00003 3421 6 Skin 0.29 protein_coding missense_variant MODERATE 70G>A Ala24Thr
M0012286 BKBILMHE_00003 4642 8 Skin 0.38 protein_coding synonymous_variant LOW 1291T>C Leu431Leu
M0012287 BKBILMHE_00003 4947 9 Skin 0.43 protein_coding synonymous_variant LOW 1596T>C Ile532Ile
M0012288 BKBILMHE_00003 4975 4 Skin 0.19 protein_coding missense_variant MODERATE 1624C>A Pro542Thr
M0012289 BKBILMHE_00005 6289 3 Skin 0.14 protein_coding synonymous_variant LOW 585G>A Leu195Leu
M0012290 BKBILMHE_00001 281 6 Skin 0.29 protein_coding synonymous_variant LOW 123G>A Ala41Ala
M0012291 BKBILMHE_00001 353 5 Skin 0.24 protein_coding synonymous_variant LOW 195T>C Ser65Ser
M0012292 BKBILMHE_00002 836 9 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -255A>G None
M0012293 BKBILMHE_00002 877 5 Skin 0.24 protein_coding upstream_gene_variant MODIFIER -214G>C None
M0012294 BKBILMHE_00002 946 4 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -145C>T None
M0012295 BKBILMHE_00002 971 4 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -120A>T None
M0012296 BKBILMHE_00002 973 10 Skin 0.48 protein_coding upstream_gene_variant MODIFIER -118C>T None
M0012297 BKBILMHE_00002 1536 8 Skin 0.38 protein_coding missense_variant MODERATE 446T>C Phe149Ser
M0012298 BKBILMHE_00002 1783 7 Skin 0.33 protein_coding synonymous_variant LOW 693C>T Ile231Ile
M0012299 BKBILMHE_00002 2312 9 Skin 0.43 protein_coding missense_variant MODERATE 1222G>A Gly408Ser
M0012300 BKBILMHE_00002 2503 8 Skin 0.38 protein_coding synonymous_variant LOW 1413T>C Tyr471Tyr
M0012301 BKBILMHE_00002 2572 8 Skin 0.38 protein_coding synonymous_variant LOW 1482A>C Thr494Thr
M0012302 BKBILMHE_00002 2725 6 Skin 0.29 protein_coding synonymous_variant LOW 1635T>C Arg545Arg
M0012303 BKBILMHE_00002 2775 7 Skin 0.33 protein_coding missense_variant MODERATE 1685G>A Arg562His
M0012304 BKBILMHE_00002 2810 5 Skin 0.24 protein_coding synonymous_variant LOW 1720C>A Arg574Arg
M0012305 BKBILMHE_00003 3734 3 Skin 0.14 protein_coding missense_variant MODERATE 383G>A Arg128His
M0012306 BKBILMHE_00003 5079 6 Skin 0.29 protein_coding synonymous_variant LOW 1728T>C Ala576Ala
M0012307 BKBILMHE_00003 5226 5 Skin 0.24 protein_coding synonymous_variant LOW 1875T>C Asn625Asn
M0012308 BKBILMHE_00003 5288 3 Skin 0.14 protein_coding missense_variant MODERATE 1937C>T Ser646Leu
M0012309 BKBILMHE_00001 362 6 Skin 0.29 protein_coding synonymous_variant LOW 204A>G Lys68Lys
M0012310 BKBILMHE_00002 2917 5 Skin 0.24 protein_coding synonymous_variant LOW 1827A>G Ala609Ala
M0012311 BKBILMHE_00003 3438 3 Skin 0.14 protein_coding synonymous_variant LOW 87A>G Glu29Glu
M0012312 BKBILMHE_00003 3654 3 Skin 0.14 protein_coding synonymous_variant LOW 303C>T Ala101Ala
M0012313 BKBILMHE_00002 1003 3 Skin 0.14 protein_coding upstream_gene_variant MODIFIER -88G>A None
M0012314 BKBILMHE_00002 1048 6 Skin 0.29 protein_coding upstream_gene_variant MODIFIER -43C>T None
M0012315 BKBILMHE_00002 1064 5 Skin 0.24 protein_coding upstream_gene_variant MODIFIER -27G>A None
M0012316 BKBILMHE_00002 1561 3 Skin 0.14 protein_coding synonymous_variant LOW 471T>C Tyr157Tyr






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term