Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1726
  Reference Plasmid   1111525849639130_bin.11__k141_183584
  Reference Plasmid Size   20736
  Reference Plasmid GC Content   0.48
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0117892 OEPEJKCE_00015 9802 4 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -39G>C None
M0117893 OEPEJKCE_00015 10062 4 Oral 0.50 protein_coding synonymous_variant LOW 222T>C Ile74Ile
M0117894 OEPEJKCE_00015 10093 3 Oral 0.38 protein_coding synonymous_variant LOW 253T>C Leu85Leu
M0117895 OEPEJKCE_00015 10191 3 Oral 0.38 protein_coding synonymous_variant LOW 351G>A Thr117Thr
M0117896 OEPEJKCE_00015 10561 3 Oral 0.38 protein_coding missense_variant MODERATE 721G>C Ala241Pro
M0117897 OEPEJKCE_00017 11867 3 Oral 0.38 protein_coding synonymous_variant LOW 354A>C Gly118Gly
M0117898 OEPEJKCE_00018 12008 3 Oral 0.38 protein_coding missense_variant MODERATE 13A>G Ile5Val
M0117899 OEPEJKCE_00018 12197 3 Oral 0.38 protein_coding missense_variant MODERATE 202T>G Ser68Ala
M0117900 OEPEJKCE_00018 12301 3 Oral 0.38 protein_coding synonymous_variant LOW 306A>G Glu102Glu
M0117901 OEPEJKCE_00018 12553 3 Oral 0.38 protein_coding synonymous_variant LOW 558T>C Ala186Ala
M0117902 OEPEJKCE_00018 12832 3 Oral 0.38 protein_coding synonymous_variant LOW 837A>G Lys279Lys
M0117903 OEPEJKCE_00018 12985 3 Oral 0.38 protein_coding synonymous_variant LOW 990T>C Cys330Cys
M0117904 OEPEJKCE_00018 13193 3 Oral 0.38 protein_coding synonymous_variant LOW 1198T>C Leu400Leu
M0117905 OEPEJKCE_00018 13246 3 Oral 0.38 protein_coding synonymous_variant LOW 1251A>G Leu417Leu
M0117906 OEPEJKCE_00018 13366 3 Oral 0.38 protein_coding synonymous_variant LOW 1371C>T Arg457Arg
M0117907 OEPEJKCE_00018 13393 3 Oral 0.38 protein_coding synonymous_variant LOW 1398A>G Ser466Ser
M0117908 OEPEJKCE_00018 13451 3 Oral 0.38 protein_coding missense_variant MODERATE 1456A>G Ile486Val
M0117909 OEPEJKCE_00018 13667 3 Oral 0.38 protein_coding missense_variant MODERATE 1672C>T Pro558Ser
M0117910 OEPEJKCE_00018 13723 3 Oral 0.38 protein_coding synonymous_variant LOW 1728T>C Arg576Arg
M0117911 OEPEJKCE_00018 13741 3 Oral 0.38 protein_coding synonymous_variant LOW 1746T>A Pro582Pro
M0117912 OEPEJKCE_00018 13849 3 Oral 0.38 protein_coding synonymous_variant LOW 1854A>G Ala618Ala
M0117913 OEPEJKCE_00019 15047 3 Oral 0.38 protein_coding synonymous_variant LOW 918C>G Ala306Ala
M0117914 OEPEJKCE_00019 15209 3 Oral 0.38 protein_coding synonymous_variant LOW 1080A>C Ala360Ala
M0117915 OEPEJKCE_00019 15551 3 Oral 0.38 protein_coding synonymous_variant LOW 1422T>C Tyr474Tyr
M0117916 OEPEJKCE_00019 15791 3 Oral 0.38 protein_coding synonymous_variant LOW 1662T>G Arg554Arg
M0117917 OEPEJKCE_00019 15848 3 Oral 0.38 protein_coding synonymous_variant LOW 1719T>C Leu573Leu
M0117918 OEPEJKCE_00019 15938 3 Oral 0.38 protein_coding synonymous_variant LOW 1809T>C Thr603Thr
M0117919 OEPEJKCE_00019 15953 3 Oral 0.38 protein_coding synonymous_variant LOW 1824C>T Asp608Asp
M0117920 OEPEJKCE_00019 15974 3 Oral 0.38 protein_coding synonymous_variant LOW 1845A>G Thr615Thr
M0117921 OEPEJKCE_00019 16113 3 Oral 0.38 protein_coding missense_variant MODERATE 1984A>G Thr662Ala
M0117922 OEPEJKCE_00019 16157 3 Oral 0.38 protein_coding synonymous_variant LOW 2028T>C His676His
M0117923 OEPEJKCE_00019 16208 3 Oral 0.38 protein_coding synonymous_variant LOW 2079G>A Glu693Glu
M0117924 OEPEJKCE_00019 16241 3 Oral 0.38 protein_coding synonymous_variant LOW 2112A>C Ser704Ser
M0117925 OEPEJKCE_00019 16334 3 Oral 0.38 protein_coding synonymous_variant LOW 2205T>G Val735Val
M0117926 OEPEJKCE_00019 16460 3 Oral 0.38 protein_coding synonymous_variant LOW 2331T>C Ser777Ser
M0117927 OEPEJKCE_00019 16583 3 Oral 0.38 protein_coding synonymous_variant LOW 2454T>C Arg818Arg
M0117928 OEPEJKCE_00019 16623 3 Oral 0.38 protein_coding missense_variant MODERATE 2494A>C Lys832Gln
M0117929 OEPEJKCE_00019 16683 3 Oral 0.38 protein_coding missense_variant MODERATE 2554C>G Gln852Glu
M0117930 OEPEJKCE_00019 16700 3 Oral 0.38 protein_coding synonymous_variant LOW 2571T>C Ser857Ser
M0117931 OEPEJKCE_00019 17024 3 Oral 0.38 protein_coding synonymous_variant LOW 2895T>G Gly965Gly
M0117932 OEPEJKCE_00019 17048 3 Oral 0.38 protein_coding synonymous_variant LOW 2919A>G Pro973Pro
M0117933 OEPEJKCE_00021 18187 3 Oral 0.38 protein_coding missense_variant MODERATE 274C>A Leu92Ile
M0117934 OEPEJKCE_00021 18306 3 Oral 0.38 protein_coding synonymous_variant LOW 393T>C Asn131Asn
M0117935 OEPEJKCE_00022 18528 3 Oral 0.38 protein_coding synonymous_variant LOW 67A>C Arg23Arg
M0117936 OEPEJKCE_00022 18869 3 Oral 0.38 protein_coding synonymous_variant LOW 408G>A Thr136Thr
M0117937 OEPEJKCE_00022 18905 3 Oral 0.38 protein_coding synonymous_variant LOW 444C>T Phe148Phe
M0117938 OEPEJKCE_00022 18908 3 Oral 0.38 protein_coding synonymous_variant LOW 447C>T Ala149Ala
M0117939 OEPEJKCE_00022 18911 3 Oral 0.38 protein_coding synonymous_variant LOW 450T>C Ala150Ala
M0117940 OEPEJKCE_00022 18950 3 Oral 0.38 protein_coding synonymous_variant LOW 489C>T His163His
M0117941 OEPEJKCE_00022 19004 3 Oral 0.38 protein_coding synonymous_variant LOW 543T>A Val181Val
M0117942 OEPEJKCE_00022 19007 3 Oral 0.38 protein_coding synonymous_variant LOW 546A>G Leu182Leu
M0117943 OEPEJKCE_00022 19089 3 Oral 0.38 protein_coding synonymous_variant LOW 628A>C Arg210Arg
M0117944 OEPEJKCE_00022 19118 3 Oral 0.38 protein_coding synonymous_variant LOW 657A>T Thr219Thr
M0117945 OEPEJKCE_00022 19158 3 Oral 0.38 protein_coding missense_variant MODERATE 697A>G Ser233Gly
M0117946 OEPEJKCE_00022 19199 3 Oral 0.38 protein_coding synonymous_variant LOW 738T>C Asn246Asn
M0117947 OEPEJKCE_00022 19259 3 Oral 0.38 protein_coding synonymous_variant LOW 798A>G Thr266Thr
M0117948 OEPEJKCE_00022 19400 3 Oral 0.38 protein_coding synonymous_variant LOW 939A>G Gln313Gln
M0117949 OEPEJKCE_00022 19418 3 Oral 0.38 protein_coding synonymous_variant LOW 957G>T Ala319Ala
M0117950 OEPEJKCE_00022 19440 3 Oral 0.38 protein_coding missense_variant MODERATE 979G>C Val327Leu
M0117951 OEPEJKCE_00022 19552 3 Oral 0.38 protein_coding missense_variant MODERATE 1091A>C Glu364Ala
M0117952 OEPEJKCE_00023 20015 3 Oral 0.38 protein_coding missense_variant MODERATE 131G>A Arg44Gln
M0117953 OEPEJKCE_00024 20369 3 Oral 0.38 protein_coding synonymous_variant LOW 255C>G Ala85Ala
M0117954 OEPEJKCE_00024 20399 3 Oral 0.38 protein_coding synonymous_variant LOW 285A>G Ala95Ala
M0117955 OEPEJKCE_00004 1501 3 Oral 0.38 protein_coding synonymous_variant LOW 225A>G Arg75Arg
M0117956 OEPEJKCE_00004 1548 3 Oral 0.38 protein_coding missense_variant MODERATE 272A>T Tyr91Phe
M0117957 OEPEJKCE_00005 1793 3 Oral 0.38 protein_coding synonymous_variant LOW 78C>T His26His
M0117958 OEPEJKCE_00005 1835 3 Oral 0.38 protein_coding synonymous_variant LOW 120C>T Ala40Ala
M0117959 OEPEJKCE_00005 1847 3 Oral 0.38 protein_coding synonymous_variant LOW 132A>G Gln44Gln
M0117960 OEPEJKCE_00005 1853 3 Oral 0.38 protein_coding synonymous_variant LOW 138T>C Gly46Gly
M0117961 OEPEJKCE_00005 1904 3 Oral 0.38 protein_coding synonymous_variant LOW 189G>A Lys63Lys
M0117962 OEPEJKCE_00005 2006 3 Oral 0.38 protein_coding synonymous_variant LOW 291A>G Ser97Ser
M0117963 OEPEJKCE_00005 2288 3 Oral 0.38 protein_coding synonymous_variant LOW 573C>T His191His
M0117964 OEPEJKCE_00005 2291 3 Oral 0.38 protein_coding synonymous_variant LOW 576C>A Arg192Arg
M0117965 OEPEJKCE_00014 8951 3 Oral 0.38 protein_coding missense_variant MODERATE 435T>G Asp145Glu
M0117966 OEPEJKCE_00014 9005 3 Oral 0.38 protein_coding synonymous_variant LOW 489T>C Gly163Gly
M0117967 OEPEJKCE_00014 9017 3 Oral 0.38 protein_coding synonymous_variant LOW 501G>C Ala167Ala
M0117968 OEPEJKCE_00014 9041 3 Oral 0.38 protein_coding synonymous_variant LOW 525T>C Asp175Asp
M0117969 OEPEJKCE_00014 9098 3 Oral 0.38 protein_coding synonymous_variant LOW 582A>G Leu194Leu
M0117970 OEPEJKCE_00014 9145 3 Oral 0.38 protein_coding missense_variant MODERATE 629A>G Asn210Ser
M0117971 OEPEJKCE_00014 9332 3 Oral 0.38 protein_coding synonymous_variant LOW 816A>G Leu272Leu
M0117972 OEPEJKCE_00014 9585 3 Oral 0.38 protein_coding missense_variant MODERATE 1069A>G Ser357Gly
M0117973 OEPEJKCE_00014 9587 3 Oral 0.38 protein_coding synonymous_variant LOW 1071C>T Ser357Ser
M0117974 OEPEJKCE_00014 9588 3 Oral 0.38 protein_coding missense_variant MODERATE 1072G>A Asp358Asn
M0117975 OEPEJKCE_00014 9593 3 Oral 0.38 protein_coding synonymous_variant LOW 1077T>C Ala359Ala
M0117976 OEPEJKCE_00014 9728 3 Oral 0.38 protein_coding synonymous_variant LOW 1212C>G Thr404Thr






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
OEPEJKCE_00002 QMT39158.1|GH23 92 9.71e-150 1 226 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term