Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1733
  Reference Plasmid   1111525849640249_bin.80__k141_1217668
  Reference Plasmid Size   21817
  Reference Plasmid GC Content   0.64
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0013114 AJINIDOJ_00023 16137 4 Skin 0.67 protein_coding missense_variant MODERATE 10A>G Ile4Val
M0013115 AJINIDOJ_00023 16445 3 Skin 0.50 protein_coding missense_variant MODERATE 318G>T Gln106His
M0013116 AJINIDOJ_00024 17542 3 Skin 0.50 protein_coding synonymous_variant LOW 945C>T Phe315Phe
M0013117 AJINIDOJ_00024 17554 3 Skin 0.50 protein_coding missense_variant MODERATE 933C>G Phe311Leu
M0013118 AJINIDOJ_00024 17715 3 Skin 0.50 protein_coding missense_variant MODERATE 772G>A Val258Ile
M0013119 AJINIDOJ_00024 17743 3 Skin 0.50 protein_coding synonymous_variant LOW 744A>G Ala248Ala
M0013120 AJINIDOJ_00024 17771 3 Skin 0.50 protein_coding missense_variant MODERATE 716T>C Val239Ala
M0013121 AJINIDOJ_00024 17889 3 Skin 0.50 protein_coding missense_variant MODERATE 598T>G Ser200Ala
M0013122 AJINIDOJ_00024 17914 3 Skin 0.50 protein_coding missense_variant MODERATE 573G>C Leu191Phe
M0013123 AJINIDOJ_00024 17922 3 Skin 0.50 protein_coding missense_variant MODERATE 565C>G Leu189Val
M0013124 AJINIDOJ_00024 18139 3 Skin 0.50 protein_coding synonymous_variant LOW 348C>T Asn116Asn
M0013125 AJINIDOJ_00024 18142 3 Skin 0.50 protein_coding synonymous_variant LOW 345G>T Val115Val
M0013126 AJINIDOJ_00024 18144 3 Skin 0.50 protein_coding missense_variant MODERATE 343G>C Val115Leu
M0013127 AJINIDOJ_00024 18148 3 Skin 0.50 protein_coding synonymous_variant LOW 339G>T Ser113Ser
M0013128 AJINIDOJ_00024 18160 3 Skin 0.50 protein_coding missense_variant MODERATE 327A>C Arg109Ser
M0013129 AJINIDOJ_00024 18162 3 Skin 0.50 protein_coding synonymous_variant LOW 325A>C Arg109Arg
M0013130 AJINIDOJ_00024 18164 3 Skin 0.50 protein_coding missense_variant MODERATE 323G>C Gly108Ala
M0013131 AJINIDOJ_00025 18632 3 Skin 0.50 protein_coding missense_variant MODERATE 390T>G Ile130Met
M0013132 AJINIDOJ_00025 18982 3 Skin 0.50 protein_coding missense_variant MODERATE 40A>C Thr14Pro
M0013133 AJINIDOJ_00024 19266 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -780T>C None
M0013134 AJINIDOJ_00024 19324 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -838T>C None
M0013135 AJINIDOJ_00024 19352 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -866T>C None
M0013136 AJINIDOJ_00026 19593 3 Skin 0.50 protein_coding missense_variant MODERATE 177T>A Asp59Glu
M0013137 AJINIDOJ_00027 19688 3 Skin 0.50 protein_coding synonymous_variant LOW 90C>G Pro30Pro
M0013138 AJINIDOJ_00027 19805 3 Skin 0.50 protein_coding synonymous_variant LOW 207A>G Pro69Pro
M0013139 AJINIDOJ_00029 20087 3 Skin 0.50 protein_coding missense_variant MODERATE 24A>G Ile8Met
M0013140 AJINIDOJ_00029 20128 3 Skin 0.50 protein_coding missense_variant MODERATE 65C>T Ser22Phe
M0013141 AJINIDOJ_00029 20141 3 Skin 0.50 protein_coding synonymous_variant LOW 78C>T Phe26Phe
M0013142 AJINIDOJ_00029 20142 3 Skin 0.50 protein_coding missense_variant MODERATE 79G>T Val27Leu
M0013143 AJINIDOJ_00029 20182 3 Skin 0.50 protein_coding missense_variant MODERATE 119G>C Arg40Pro
M0013144 AJINIDOJ_00029 20348 3 Skin 0.50 protein_coding missense_variant MODERATE 285C>G Asp95Glu
M0013145 AJINIDOJ_00024 20403 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -1917G>A None
M0013146 AJINIDOJ_00024 20598 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -2112G>C None
M0013147 AJINIDOJ_00020 13262 3 Skin 0.50 protein_coding synonymous_variant LOW 2001A>C Gly667Gly
M0013148 AJINIDOJ_00020 13616 3 Skin 0.50 protein_coding synonymous_variant LOW 2355A>G Glu785Glu
M0013149 AJINIDOJ_00020 13646 3 Skin 0.50 protein_coding synonymous_variant LOW 2385A>G Pro795Pro
M0013150 AJINIDOJ_00020 13712 3 Skin 0.50 protein_coding synonymous_variant LOW 2451G>A Lys817Lys
M0013151 AJINIDOJ_00020 13715 3 Skin 0.50 protein_coding synonymous_variant LOW 2454A>G Arg818Arg
M0013152 AJINIDOJ_00020 13718 3 Skin 0.50 protein_coding synonymous_variant LOW 2457T>C Asp819Asp
M0013153 AJINIDOJ_00020 13747 3 Skin 0.50 protein_coding missense_variant MODERATE 2486C>T Ala829Val
M0013154 AJINIDOJ_00020 13786 3 Skin 0.50 protein_coding missense_variant MODERATE 2525C>T Pro842Leu
M0013155 AJINIDOJ_00020 13817 3 Skin 0.50 protein_coding synonymous_variant LOW 2556T>C Val852Val
M0013156 AJINIDOJ_00020 13862 3 Skin 0.50 protein_coding synonymous_variant LOW 2601G>A Arg867Arg
M0013157 AJINIDOJ_00020 13931 3 Skin 0.50 protein_coding synonymous_variant LOW 2670A>G Arg890Arg
M0013158 AJINIDOJ_00020 14204 3 Skin 0.50 protein_coding synonymous_variant LOW 2943G>A Glu981Glu
M0013159 AJINIDOJ_00022 15720 3 Skin 0.50 protein_coding synonymous_variant LOW 168C>G Ser56Ser






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term