Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1740
  Reference Plasmid   1111525849640317_bin.11__k141_42330
  Reference Plasmid Size   5598
  Reference Plasmid GC Content   0.72
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0013199 MDLKKDCM_00002 4896 6 Skin 0.55 protein_coding upstream_gene_variant MODIFIER -3183T>C None
M0013200 MDLKKDCM_00002 5019 3 Skin 0.27 protein_coding upstream_gene_variant MODIFIER -3306C>T None
M0013201 MDLKKDCM_00002 5136 5 Skin 0.45 protein_coding upstream_gene_variant MODIFIER -3423C>T None
M0013202 MDLKKDCM_00002 5517 6 Skin 0.55 protein_coding upstream_gene_variant MODIFIER -3804A>G None
M0013203 MDLKKDCM_00004 3544 3 Skin 0.27 protein_coding synonymous_variant LOW 795T>C Arg265Arg
M0013204 MDLKKDCM_00004 3556 3 Skin 0.27 protein_coding synonymous_variant LOW 807G>C Ala269Ala
M0013205 MDLKKDCM_00004 3575 4 Skin 0.36 protein_coding missense_variant MODERATE 826C>G Pro276Ala
M0013206 MDLKKDCM_00004 3590 4 Skin 0.36 protein_coding missense_variant MODERATE 841C>A Leu281Ile
M0013207 MDLKKDCM_00004 4651 3 Skin 0.27 protein_coding synonymous_variant LOW 1902G>A Ser634Ser
M0013208 MDLKKDCM_00001 647 5 Skin 0.45 protein_coding missense_variant MODERATE 478G>A Glu160Lys
M0013209 MDLKKDCM_00001 1060 3 Skin 0.27 protein_coding synonymous_variant LOW 891T>C Arg297Arg
M0013210 MDLKKDCM_00004 3970 3 Skin 0.27 protein_coding synonymous_variant LOW 1221T>C Ala407Ala
M0013211 MDLKKDCM_00002 5061 3 Skin 0.27 protein_coding upstream_gene_variant MODIFIER -3348C>T None
M0013212 MDLKKDCM_00002 5109 3 Skin 0.27 protein_coding upstream_gene_variant MODIFIER -3396T>C None
M0013213 MDLKKDCM_00002 5193 3 Skin 0.27 protein_coding upstream_gene_variant MODIFIER -3480C>G None
M0013214 MDLKKDCM_00002 5196 3 Skin 0.27 protein_coding upstream_gene_variant MODIFIER -3483G>C None
M0013215 MDLKKDCM_00002 5220 3 Skin 0.27 protein_coding upstream_gene_variant MODIFIER -3507A>G None
M0013216 MDLKKDCM_00002 5262 3 Skin 0.27 protein_coding upstream_gene_variant MODIFIER -3549G>C None
M0013217 MDLKKDCM_00002 5272 3 Skin 0.27 protein_coding upstream_gene_variant MODIFIER -3559C>T None
M0013218 MDLKKDCM_00002 5343 3 Skin 0.27 protein_coding upstream_gene_variant MODIFIER -3630C>A None
M0013219 MDLKKDCM_00002 5344 3 Skin 0.27 protein_coding upstream_gene_variant MODIFIER -3631A>G None
M0013220 MDLKKDCM_00002 5346 3 Skin 0.27 protein_coding upstream_gene_variant MODIFIER -3633C>G None
M0013221 MDLKKDCM_00003 1869 4 Skin 0.36 protein_coding synonymous_variant LOW 714C>T Arg238Arg
M0013222 MDLKKDCM_00004 3106 3 Skin 0.27 protein_coding synonymous_variant LOW 357C>G Gly119Gly
M0013223 MDLKKDCM_00004 3453 3 Skin 0.27 protein_coding missense_variant MODERATE 704G>A Arg235Gln
M0013224 MDLKKDCM_00004 3487 3 Skin 0.27 protein_coding synonymous_variant LOW 738C>T Ala246Ala
M0013225 MDLKKDCM_00004 3490 3 Skin 0.27 protein_coding synonymous_variant LOW 741G>C Ala247Ala
M0013226 MDLKKDCM_00004 3492 3 Skin 0.27 protein_coding missense_variant MODERATE 743G>T Arg248Leu
M0013227 MDLKKDCM_00004 3496 3 Skin 0.27 protein_coding synonymous_variant LOW 747A>G Pro249Pro
M0013228 MDLKKDCM_00003 2124 4 Skin 0.36 protein_coding synonymous_variant LOW 459C>G Gly153Gly
M0013229 MDLKKDCM_00003 2127 4 Skin 0.36 protein_coding synonymous_variant LOW 456G>A Gln152Gln
M0013230 MDLKKDCM_00004 2827 4 Skin 0.36 protein_coding synonymous_variant LOW 78G>A Glu26Glu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term