Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1747
  Reference Plasmid   1111525849641655_bin.6__k141_13469
  Reference Plasmid Size   14557
  Reference Plasmid GC Content   0.67
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0013410 BNCMHHHK_00008 9302 3 Skin 0.27 protein_coding synonymous_variant LOW 276A>G Lys92Lys
M0013411 BNCMHHHK_00008 9307 3 Skin 0.27 protein_coding missense_variant MODERATE 281C>T Ala94Val
M0013412 BNCMHHHK_00008 9326 3 Skin 0.27 protein_coding synonymous_variant LOW 300A>G Gln100Gln
M0013413 BNCMHHHK_00008 9636 3 Skin 0.27 protein_coding missense_variant MODERATE 610G>A Ala204Thr
M0013414 BNCMHHHK_00009 11438 3 Skin 0.27 protein_coding synonymous_variant LOW 1374T>C Ala458Ala
M0013415 BNCMHHHK_00009 11450 3 Skin 0.27 protein_coding synonymous_variant LOW 1386T>C Val462Val
M0013416 BNCMHHHK_00010 12222 3 Skin 0.27 protein_coding upstream_gene_variant MODIFIER -19G>C None
M0013417 BNCMHHHK_00010 12333 5 Skin 0.45 protein_coding synonymous_variant LOW 93C>T Thr31Thr
M0013418 BNCMHHHK_00010 12336 5 Skin 0.45 protein_coding synonymous_variant LOW 96T>C Ala32Ala
M0013419 BNCMHHHK_00010 12412 6 Skin 0.55 protein_coding missense_variant MODERATE 172A>G Thr58Ala
M0013420 BNCMHHHK_00010 12446 6 Skin 0.55 protein_coding missense_variant MODERATE 206A>G Asn69Ser
M0013421 BNCMHHHK_00010 12453 6 Skin 0.55 protein_coding synonymous_variant LOW 213T>C Gly71Gly
M0013422 BNCMHHHK_00010 12501 8 Skin 0.73 protein_coding synonymous_variant LOW 261T>C Ala87Ala
M0013423 BNCMHHHK_00011 13407 4 Skin 0.36 protein_coding missense_variant MODERATE 874G>A Asp292Asn
M0013424 BNCMHHHK_00011 13859 6 Skin 0.55 protein_coding synonymous_variant LOW 1326T>G Ala442Ala
M0013425 BNCMHHHK_00011 13890 6 Skin 0.55 protein_coding missense_variant MODERATE 1357A>T Thr453Ser
M0013426 BNCMHHHK_00011 14045 7 Skin 0.64 protein_coding synonymous_variant LOW 1512C>T Arg504Arg
M0013427 BNCMHHHK_00012 14128 6 Skin 0.55 protein_coding synonymous_variant LOW 66A>G Arg22Arg
M0013428 BNCMHHHK_00012 14146 6 Skin 0.55 protein_coding synonymous_variant LOW 84T>G Leu28Leu
M0013429 BNCMHHHK_00012 14164 6 Skin 0.55 protein_coding synonymous_variant LOW 102A>G Val34Val
M0013430 BNCMHHHK_00012 14168 6 Skin 0.55 protein_coding missense_variant MODERATE 106G>T Ala36Ser
M0013431 BNCMHHHK_00012 14174 6 Skin 0.55 protein_coding missense_variant MODERATE 112G>A Val38Met
M0013432 BNCMHHHK_00012 14188 6 Skin 0.55 protein_coding synonymous_variant LOW 126G>C Ser42Ser
M0013433 BNCMHHHK_00012 14189 6 Skin 0.55 protein_coding missense_variant MODERATE 127A>C Met43Leu
M0013434 BNCMHHHK_00011 13364 4 Skin 0.36 protein_coding synonymous_variant LOW 831G>T Val277Val
M0013435 BNCMHHHK_00011 13997 7 Skin 0.64 protein_coding synonymous_variant LOW 1464C>T Arg488Arg
M0013436 BNCMHHHK_00009 12101 4 Skin 0.36 protein_coding synonymous_variant LOW 2037G>A Glu679Glu
M0013437 BNCMHHHK_00010 12528 4 Skin 0.36 protein_coding synonymous_variant LOW 288T>C Val96Val
M0013438 BNCMHHHK_00008 9779 3 Skin 0.27 protein_coding synonymous_variant LOW 753C>G Ala251Ala
M0013439 BNCMHHHK_00008 9783 3 Skin 0.27 protein_coding missense_variant MODERATE 757G>A Gly253Ser
M0013440 BNCMHHHK_00008 9837 5 Skin 0.45 protein_coding missense_variant MODERATE 811C>G Arg271Gly
M0013441 BNCMHHHK_00011 12833 3 Skin 0.27 protein_coding synonymous_variant LOW 300T>C Asn100Asn
M0013442 BNCMHHHK_00011 12848 3 Skin 0.27 protein_coding synonymous_variant LOW 315A>G Pro105Pro






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term