Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1785
  Reference Plasmid   1111525849644392_bin.21__k141_34294
  Reference Plasmid Size   24404
  Reference Plasmid GC Content   0.68
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0015200 NOLHGKCK_00006 6001 3 Skin 0.20 protein_coding missense_variant MODERATE 266A>C Asp89Ala
M0015201 NOLHGKCK_00006 6012 3 Skin 0.20 protein_coding synonymous_variant LOW 255C>G Leu85Leu
M0015202 NOLHGKCK_00006 6024 3 Skin 0.20 protein_coding synonymous_variant LOW 243C>T Phe81Phe
M0015203 NOLHGKCK_00006 6027 3 Skin 0.20 protein_coding synonymous_variant LOW 240T>C Ala80Ala
M0015204 NOLHGKCK_00006 6054 3 Skin 0.20 protein_coding synonymous_variant LOW 213T>C Ser71Ser
M0015205 NOLHGKCK_00006 6056 3 Skin 0.20 protein_coding missense_variant MODERATE 211T>A Ser71Thr
M0015206 NOLHGKCK_00006 6066 3 Skin 0.20 protein_coding missense_variant MODERATE 201T>G Phe67Leu
M0015207 NOLHGKCK_00006 6068 3 Skin 0.20 protein_coding missense_variant MODERATE 199T>C Phe67Leu
M0015208 NOLHGKCK_00006 6156 3 Skin 0.20 protein_coding synonymous_variant LOW 111A>G Glu37Glu
M0015209 NOLHGKCK_00006 6235 3 Skin 0.20 protein_coding missense_variant MODERATE 32C>A Pro11Gln
M0015210 NOLHGKCK_00002 6271 3 Skin 0.20 protein_coding upstream_gene_variant MODIFIER -4184T>A None
M0015211 NOLHGKCK_00002 6284 3 Skin 0.20 protein_coding upstream_gene_variant MODIFIER -4197T>C None
M0015212 NOLHGKCK_00002 6285 3 Skin 0.20 protein_coding upstream_gene_variant MODIFIER -4198T>C None
M0015213 NOLHGKCK_00007 6336 3 Skin 0.20 protein_coding synonymous_variant LOW 522G>C Leu174Leu
M0015214 NOLHGKCK_00007 6552 3 Skin 0.20 protein_coding synonymous_variant LOW 306C>G Leu102Leu
M0015215 NOLHGKCK_00007 6603 3 Skin 0.20 protein_coding synonymous_variant LOW 255T>C Ser85Ser
M0015216 NOLHGKCK_00007 6645 3 Skin 0.20 protein_coding synonymous_variant LOW 213C>G Ala71Ala
M0015217 NOLHGKCK_00007 6655 3 Skin 0.20 protein_coding missense_variant MODERATE 203G>A Arg68Gln
M0015218 NOLHGKCK_00007 6720 3 Skin 0.20 protein_coding synonymous_variant LOW 138G>C Gly46Gly
M0015219 NOLHGKCK_00007 6735 3 Skin 0.20 protein_coding synonymous_variant LOW 123C>T Asp41Asp
M0015220 NOLHGKCK_00007 6792 4 Skin 0.27 protein_coding synonymous_variant LOW 66G>C Val22Val
M0015221 NOLHGKCK_00007 6801 3 Skin 0.20 protein_coding synonymous_variant LOW 57C>T His19His
M0015222 NOLHGKCK_00007 6804 3 Skin 0.20 protein_coding synonymous_variant LOW 54C>G Thr18Thr
M0015223 NOLHGKCK_00007 6849 3 Skin 0.20 protein_coding synonymous_variant LOW 9A>G Gln3Gln
M0015224 NOLHGKCK_00002 6918 3 Skin 0.20 protein_coding upstream_gene_variant MODIFIER -4831T>C None
M0015225 NOLHGKCK_00002 6948 3 Skin 0.20 protein_coding upstream_gene_variant MODIFIER -4861A>C None
M0015226 NOLHGKCK_00002 7030 3 Skin 0.20 protein_coding upstream_gene_variant MODIFIER -4943T>C None
M0015227 NOLHGKCK_00002 7033 3 Skin 0.20 protein_coding upstream_gene_variant MODIFIER -4946C>T None
M0015228 NOLHGKCK_00003 7146 3 Skin 0.20 protein_coding upstream_gene_variant MODIFIER -4076A>C None
M0015229 NOLHGKCK_00003 7236 3 Skin 0.20 protein_coding upstream_gene_variant MODIFIER -4166T>G None
M0015230 NOLHGKCK_00008 7309 3 Skin 0.20 protein_coding missense_variant MODERATE 69G>C Glu23Asp
M0015231 NOLHGKCK_00008 7313 3 Skin 0.20 protein_coding missense_variant MODERATE 73A>T Thr25Ser
M0015232 NOLHGKCK_00008 7316 3 Skin 0.20 protein_coding missense_variant MODERATE 76G>C Asp26His






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term