Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1786
  Reference Plasmid   1111525849644392_bin.21__k141_405121
  Reference Plasmid Size   9946
  Reference Plasmid GC Content   0.67
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0015233 LAIDLGLI_00008 6602 3 Skin 0.43 protein_coding synonymous_variant LOW 2676G>C Thr892Thr
M0015234 LAIDLGLI_00008 6913 3 Skin 0.43 protein_coding synonymous_variant LOW 2365T>C Leu789Leu
M0015235 LAIDLGLI_00008 7066 3 Skin 0.43 protein_coding missense_variant MODERATE 2212A>T Met738Leu
M0015236 LAIDLGLI_00008 7117 4 Skin 0.57 protein_coding synonymous_variant LOW 2161A>C Arg721Arg
M0015237 LAIDLGLI_00008 8006 4 Skin 0.57 protein_coding synonymous_variant LOW 1272G>C Ala424Ala
M0015238 LAIDLGLI_00008 8075 3 Skin 0.43 protein_coding synonymous_variant LOW 1203A>G Ala401Ala
M0015239 LAIDLGLI_00008 8566 3 Skin 0.43 protein_coding missense_variant MODERATE 712C>G His238Asp
M0015240 LAIDLGLI_00009 9325 3 Skin 0.43 protein_coding synonymous_variant LOW 567C>G Ala189Ala
M0015241 LAIDLGLI_00009 9405 3 Skin 0.43 protein_coding missense_variant MODERATE 487A>G Met163Val
M0015242 LAIDLGLI_00009 9432 3 Skin 0.43 protein_coding synonymous_variant LOW 460T>C Leu154Leu
M0015243 LAIDLGLI_00009 9439 3 Skin 0.43 protein_coding synonymous_variant LOW 453C>T Val151Val
M0015244 LAIDLGLI_00008 7081 3 Skin 0.43 protein_coding missense_variant MODERATE 2197A>G Asn733Asp
M0015245 LAIDLGLI_00008 7094 3 Skin 0.43 protein_coding synonymous_variant LOW 2184T>C Arg728Arg
M0015246 LAIDLGLI_00008 7129 3 Skin 0.43 protein_coding missense_variant MODERATE 2149A>G Thr717Ala
M0015247 LAIDLGLI_00008 7289 3 Skin 0.43 protein_coding synonymous_variant LOW 1989T>C Ala663Ala
M0015248 LAIDLGLI_00008 7337 3 Skin 0.43 protein_coding synonymous_variant LOW 1941T>C Thr647Thr






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term