Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1774
  Reference Plasmid   1111525849644392_bin.2__k141_188111
  Reference Plasmid Size   13371
  Reference Plasmid GC Content   0.71
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0015297 EGNLMBHJ_00008 9243 4 Skin 0.57 protein_coding upstream_gene_variant MODIFIER -120C>A None
M0015298 EGNLMBHJ_00008 9253 4 Skin 0.57 protein_coding upstream_gene_variant MODIFIER -110C>G None
M0015299 EGNLMBHJ_00008 9265 4 Skin 0.57 protein_coding upstream_gene_variant MODIFIER -98C>T None
M0015300 EGNLMBHJ_00008 9311 4 Skin 0.57 protein_coding upstream_gene_variant MODIFIER -52C>A None
M0015301 EGNLMBHJ_00008 9471 4 Skin 0.57 protein_coding missense_variant MODERATE 109T>A Ser37Thr
M0015302 EGNLMBHJ_00008 9835 4 Skin 0.57 protein_coding missense_variant MODERATE 473T>C Val158Ala
M0015303 EGNLMBHJ_00009 11680 4 Skin 0.57 protein_coding synonymous_variant LOW 690A>C Gly230Gly
M0015304 EGNLMBHJ_00009 11917 4 Skin 0.57 protein_coding synonymous_variant LOW 927C>G Arg309Arg
M0015305 EGNLMBHJ_00009 11923 4 Skin 0.57 protein_coding synonymous_variant LOW 933C>G Ala311Ala
M0015306 EGNLMBHJ_00009 11938 4 Skin 0.57 protein_coding synonymous_variant LOW 948A>C Ile316Ile
M0015307 EGNLMBHJ_00009 12085 4 Skin 0.57 protein_coding synonymous_variant LOW 1095C>G Ala365Ala
M0015308 EGNLMBHJ_00009 12100 4 Skin 0.57 protein_coding synonymous_variant LOW 1110G>C Gly370Gly
M0015309 EGNLMBHJ_00009 12400 4 Skin 0.57 protein_coding synonymous_variant LOW 1410A>G Glu470Glu
M0015310 EGNLMBHJ_00009 12403 4 Skin 0.57 protein_coding synonymous_variant LOW 1413C>G Arg471Arg
M0015311 EGNLMBHJ_00009 12433 3 Skin 0.43 protein_coding synonymous_variant LOW 1443T>C Arg481Arg
M0015312 EGNLMBHJ_00009 12439 3 Skin 0.43 protein_coding synonymous_variant LOW 1449C>A Ala483Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term