Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1780
  Reference Plasmid   1111525849644392_bin.2__k141_296911
  Reference Plasmid Size   9813
  Reference Plasmid GC Content   0.72
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0015338 CCNBPKGP_00008 7305 3 Skin 0.38 protein_coding synonymous_variant LOW 1572G>C Leu524Leu
M0015339 CCNBPKGP_00008 7314 3 Skin 0.38 protein_coding synonymous_variant LOW 1581T>C Tyr527Tyr
M0015340 CCNBPKGP_00002 1242 3 Skin 0.38 protein_coding synonymous_variant LOW 510C>G Thr170Thr
M0015341 CCNBPKGP_00003 1320 3 Skin 0.38 protein_coding missense_variant MODERATE 10C>A Pro4Thr
M0015342 CCNBPKGP_00003 1335 3 Skin 0.38 protein_coding missense_variant MODERATE 25A>G Ser9Gly
M0015343 CCNBPKGP_00003 1531 3 Skin 0.38 protein_coding missense_variant MODERATE 221T>C Leu74Pro
M0015344 CCNBPKGP_00003 1559 3 Skin 0.38 protein_coding missense_variant MODERATE 249A>G Ile83Met
M0015345 CCNBPKGP_00004 2257 3 Skin 0.38 protein_coding missense_variant MODERATE 256T>C Tyr86His
M0015346 CCNBPKGP_00005 2706 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -1C>G None
M0015347 CCNBPKGP_00005 2712 3 Skin 0.38 protein_coding synonymous_variant LOW 6T>C Thr2Thr
M0015348 CCNBPKGP_00007 5713 3 Skin 0.38 protein_coding synonymous_variant LOW 780G>C Val260Val
M0015349 CCNBPKGP_00008 6213 3 Skin 0.38 protein_coding synonymous_variant LOW 480A>G Gly160Gly
M0015350 CCNBPKGP_00008 6279 3 Skin 0.38 protein_coding synonymous_variant LOW 546T>C Leu182Leu
M0015351 CCNBPKGP_00008 6343 3 Skin 0.38 protein_coding missense_variant MODERATE 610C>A Gln204Lys
M0015352 CCNBPKGP_00008 6417 3 Skin 0.38 protein_coding synonymous_variant LOW 684C>T Pro228Pro
M0015353 CCNBPKGP_00008 6441 3 Skin 0.38 protein_coding synonymous_variant LOW 708G>C Val236Val






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term