Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1794
  Reference Plasmid   1111525849644833_bin.27__k141_174187
  Reference Plasmid Size   5318
  Reference Plasmid GC Content   0.71
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0016081 CFKFHIGC_00002 906 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -440C>G None
M0016082 CFKFHIGC_00002 908 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -438C>T None
M0016083 CFKFHIGC_00002 919 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -427T>C None
M0016084 CFKFHIGC_00002 936 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -410T>C None
M0016085 CFKFHIGC_00002 938 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -408C>T None
M0016086 CFKFHIGC_00002 949 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -397A>C None
M0016087 CFKFHIGC_00002 970 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -376T>G None
M0016088 CFKFHIGC_00002 1951 3 Skin 0.43 protein_coding synonymous_variant LOW 606A>G Ala202Ala
M0016089 CFKFHIGC_00002 1957 3 Skin 0.43 protein_coding synonymous_variant LOW 612T>C Ala204Ala
M0016090 CFKFHIGC_00002 2022 3 Skin 0.43 protein_coding missense_variant MODERATE 677G>C Arg226Pro
M0016091 CFKFHIGC_00003 2419 3 Skin 0.43 protein_coding missense_variant MODERATE 138A>C Arg46Ser
M0016092 CFKFHIGC_00003 2488 4 Skin 0.57 protein_coding missense_variant MODERATE 69G>C Gln23His
M0016093 CFKFHIGC_00003 2497 3 Skin 0.43 protein_coding synonymous_variant LOW 60C>T Gly20Gly
M0016094 CFKFHIGC_00003 2513 4 Skin 0.57 protein_coding missense_variant MODERATE 44C>T Pro15Leu
M0016095 CFKFHIGC_00003 2517 4 Skin 0.57 protein_coding missense_variant MODERATE 40A>G Asn14Asp
M0016096 CFKFHIGC_00004 2607 3 Skin 0.43 protein_coding synonymous_variant LOW 321T>C Arg107Arg
M0016097 CFKFHIGC_00005 3155 3 Skin 0.43 protein_coding synonymous_variant LOW 729A>G Thr243Thr
M0016098 CFKFHIGC_00005 3210 5 Skin 0.71 protein_coding missense_variant MODERATE 674A>C Asn225Thr
M0016099 CFKFHIGC_00005 3257 3 Skin 0.43 protein_coding synonymous_variant LOW 627T>G Val209Val
M0016100 CFKFHIGC_00005 3294 4 Skin 0.57 protein_coding missense_variant MODERATE 590G>A Ser197Asn
M0016101 CFKFHIGC_00005 3455 3 Skin 0.43 protein_coding synonymous_variant LOW 429T>C Asp143Asp
M0016102 CFKFHIGC_00005 3758 5 Skin 0.71 protein_coding synonymous_variant LOW 126C>T His42His
M0016103 CFKFHIGC_00003 3988 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -1432T>C None
M0016104 CFKFHIGC_00003 4055 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -1499C>G None
M0016105 CFKFHIGC_00003 4176 5 Skin 0.71 protein_coding upstream_gene_variant MODIFIER -1620G>A None
M0016106 CFKFHIGC_00004 2790 3 Skin 0.43 protein_coding synonymous_variant LOW 138T>G Ser46Ser
M0016107 CFKFHIGC_00007 4337 4 Skin 0.57 protein_coding synonymous_variant LOW 531A>G Gln177Gln
M0016108 CFKFHIGC_00003 4893 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -2337T>C None
M0016109 CFKFHIGC_00003 4916 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -2360C>T None
M0016110 CFKFHIGC_00003 4919 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -2363T>C None
M0016111 CFKFHIGC_00003 5040 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -2484C>T None
M0016112 CFKFHIGC_00003 5056 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -2500G>C None
M0016113 CFKFHIGC_00003 5117 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -2561G>A None
M0016114 CFKFHIGC_00004 2906 3 Skin 0.43 protein_coding missense_variant MODERATE 22T>C Ser8Pro
M0016115 CFKFHIGC_00004 2917 3 Skin 0.43 protein_coding missense_variant MODERATE 11C>T Ser4Leu
M0016116 CFKFHIGC_00005 2973 3 Skin 0.43 protein_coding missense_variant MODERATE 911T>C Val304Ala
M0016117 CFKFHIGC_00005 3037 3 Skin 0.43 protein_coding synonymous_variant LOW 847T>C Leu283Leu
M0016118 CFKFHIGC_00005 3038 3 Skin 0.43 protein_coding synonymous_variant LOW 846G>A Glu282Glu
M0016119 CFKFHIGC_00007 4325 3 Skin 0.43 protein_coding missense_variant MODERATE 543C>G Asp181Glu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term