Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1798
  Reference Plasmid   1111525849645140_bin.24__k141_27358
  Reference Plasmid Size   12122
  Reference Plasmid GC Content   0.69
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0016166 MHHJOBIG_00003 2460 3 Skin 0.43 protein_coding missense_variant MODERATE 349G>T Ala117Ser
M0016167 MHHJOBIG_00003 2542 3 Skin 0.43 protein_coding synonymous_variant LOW 267T>C Phe89Phe
M0016168 MHHJOBIG_00002 3192 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -1619A>G None
M0016169 MHHJOBIG_00002 3310 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -1737T>C None
M0016170 MHHJOBIG_00002 3321 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -1748T>C None
M0016171 MHHJOBIG_00004 4771 3 Skin 0.43 protein_coding synonymous_variant LOW 1245T>C Val415Val
M0016172 MHHJOBIG_00004 4948 3 Skin 0.43 protein_coding synonymous_variant LOW 1422T>C His474His
M0016173 MHHJOBIG_00004 4963 3 Skin 0.43 protein_coding synonymous_variant LOW 1437A>G Gly479Gly
M0016174 MHHJOBIG_00004 5020 3 Skin 0.43 protein_coding synonymous_variant LOW 1494G>C Gly498Gly
M0016175 MHHJOBIG_00004 5053 3 Skin 0.43 protein_coding synonymous_variant LOW 1527T>C Tyr509Tyr
M0016176 MHHJOBIG_00004 5122 3 Skin 0.43 protein_coding synonymous_variant LOW 1596G>T Val532Val
M0016177 MHHJOBIG_00004 5125 3 Skin 0.43 protein_coding synonymous_variant LOW 1599T>C His533His
M0016178 MHHJOBIG_00004 5335 3 Skin 0.43 protein_coding synonymous_variant LOW 1809T>C Asp603Asp
M0016179 MHHJOBIG_00005 6697 3 Skin 0.43 protein_coding synonymous_variant LOW 867C>G Leu289Leu
M0016180 MHHJOBIG_00005 6739 3 Skin 0.43 protein_coding synonymous_variant LOW 825T>G Leu275Leu
M0016181 MHHJOBIG_00005 6784 3 Skin 0.43 protein_coding synonymous_variant LOW 780A>C Ala260Ala
M0016182 MHHJOBIG_00005 7339 3 Skin 0.43 protein_coding missense_variant MODERATE 225A>C Glu75Asp
M0016183 MHHJOBIG_00005 7408 3 Skin 0.43 protein_coding synonymous_variant LOW 156C>G Ala52Ala
M0016184 MHHJOBIG_00006 8196 3 Skin 0.43 protein_coding synonymous_variant LOW 1380G>C Arg460Arg
M0016185 MHHJOBIG_00006 8247 3 Skin 0.43 protein_coding synonymous_variant LOW 1329G>A Glu443Glu
M0016186 MHHJOBIG_00006 8337 3 Skin 0.43 protein_coding synonymous_variant LOW 1239G>T Leu413Leu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term