Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1813
  Reference Plasmid   1111525849645752_bin.8__k141_64781
  Reference Plasmid Size   14185
  Reference Plasmid GC Content   0.45
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0141251 MHLKOINJ_00006 5486 4 Vaginal 1.00 protein_coding synonymous_variant LOW 657C>T Leu219Leu
M0141252 MHLKOINJ_00006 5513 4 Vaginal 1.00 protein_coding synonymous_variant LOW 684T>C Val228Val
M0141253 MHLKOINJ_00006 5627 4 Vaginal 1.00 protein_coding synonymous_variant LOW 798C>T Tyr266Tyr
M0141254 MHLKOINJ_00006 5664 4 Vaginal 1.00 protein_coding missense_variant MODERATE 835A>G Thr279Ala
M0141255 MHLKOINJ_00006 5666 3 Vaginal 0.75 protein_coding synonymous_variant LOW 837A>G Thr279Thr
M0141256 MHLKOINJ_00006 5732 3 Vaginal 0.75 protein_coding synonymous_variant LOW 903T>C Ser301Ser
M0141257 MHLKOINJ_00006 5762 3 Vaginal 0.75 protein_coding synonymous_variant LOW 933C>T Asn311Asn
M0141258 MHLKOINJ_00006 5780 3 Vaginal 0.75 protein_coding synonymous_variant LOW 951G>A Thr317Thr
M0141259 MHLKOINJ_00006 5789 3 Vaginal 0.75 protein_coding synonymous_variant LOW 960T>G Ala320Ala
M0141260 MHLKOINJ_00006 5816 3 Vaginal 0.75 protein_coding synonymous_variant LOW 987T>A Thr329Thr
M0141261 MHLKOINJ_00006 6054 3 Vaginal 0.75 protein_coding missense_variant MODERATE 1225C>A Leu409Ile
M0141262 MHLKOINJ_00006 6120 3 Vaginal 0.75 protein_coding missense_variant MODERATE 1291C>A Gln431Lys
M0141263 MHLKOINJ_00006 6203 3 Vaginal 0.75 protein_coding synonymous_variant LOW 1374T>C Thr458Thr
M0141264 MHLKOINJ_00006 6251 3 Vaginal 0.75 protein_coding synonymous_variant LOW 1422A>T Thr474Thr
M0141265 MHLKOINJ_00006 6323 3 Vaginal 0.75 protein_coding synonymous_variant LOW 1494A>G Thr498Thr
M0141266 MHLKOINJ_00006 6338 3 Vaginal 0.75 protein_coding synonymous_variant LOW 1509T>C Asn503Asn
M0141267 MHLKOINJ_00006 6341 4 Vaginal 1.00 protein_coding synonymous_variant LOW 1512T>C Phe504Phe
M0141268 MHLKOINJ_00007 7219 3 Vaginal 0.75 protein_coding missense_variant MODERATE 39A>G Ile13Met
M0141269 MHLKOINJ_00006 5651 3 Vaginal 0.75 protein_coding synonymous_variant LOW 822C>T Arg274Arg






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term